Method for treating tissue through injection of a therapeutic agent

• US 6,591,129 B1
• Filed: 01/18/2000
• Issued: 07/08/2003
• Est. Priority Date: 02/15/1996
• Status: Expired due to Term

• Current Assignee: Biosense, Inc. (Cardinal Health, Inc.)
• Original Assignee: Biosense, Inc. (Cardinal Health, Inc.)
• Inventors: Ben-Haim, Shlomo, Fenster, Maier
• Primary Examiner(s): Lateef, Marvin M.
• Assistant Examiner(s): MANTIS MERCADER, ELENI M
• Application Number:
  US09/488,841
• Time in Patent Office: 1,267 Days
• Field of Search: 600/424, 600/374, 600/407, 600/427, 600/425, 128/899, 324/207.11, 606/41, 606/45, 606/48, 606/44, 606/47, 607/3, 607/120-122, 607/126-128, 607/60-61, 607/32-33, 604/66
• US Class Current: 600/424
• CPC Class Codes: A61B 10/02 Instruments for taking cell samples or for biopsy A61B10/0038 and A61B10/0045 take precedence; needle locating or guiding means A61B17/3403; samplers for enzymology or microbiology C12M1/26; sampling or preparing biological specimens G01N33/48
• CPC Class Codes: A61B 17/22012 in direct contact with, or very close to, the obstruction or concrement for removing obstructions in blood vessels by laser A61B18/245
• CPC Class Codes: A61B 17/3403 Needle locating or guiding means guides for suture needles A61B17/0482; guiding or tracking by nuclear magnetic resonance G01R33/285
• CPC Class Codes: A61B 18/20 using laser
• CPC Class Codes: A61B 2017/00247 Making holes in the wall of the heart, e.g. laser Myocardial revascularization
• CPC Class Codes: A61B 2017/22008 used or promoted
• CPC Class Codes: A61B 2018/00392 Transmyocardial revascularisation
• CPC Class Codes: A61B 2034/2051 Electromagnetic tracking systems
• CPC Class Codes: A61B 2090/378 using ultrasound
• CPC Class Codes: A61B 2090/3782 transmitter or receiver in catheter or minimal invasive instrument
• CPC Class Codes: A61B 2090/3958 emitting a signal
• CPC Class Codes: A61B 34/20 Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
• CPC Class Codes: A61B 5/06 Devices, other than using radiation, for detecting or locating foreign bodies for removing same A61B17/50 ; determining position of probes within or on the body of the patient
• CPC Class Codes: A61B 5/062 using magnetic field
• CPC Class Codes: A61B 5/063 using impedance measurements
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
• CPC Class Codes: A61B 5/6852 Catheters
• CPC Class Codes: A61B 5/6853 with a balloon
• CPC Class Codes: A61B 5/6856 with a distal loop
• CPC Class Codes: A61B 5/6858 with a distal basket, e.g. expandable basket
• CPC Class Codes: A61B 8/0841 : for locating instruments
• CPC Class Codes: A61N 5/0601 : Apparatus for use inside the body
• CPC Class Codes: A61N 5/1064 : for adjusting radiation treatment in response to monitoring
• CPC Class Codes: A61N 7/02 : Localised ultrasound hyperthermia hyperthermia in general A61F7/00

Abstract

A method for treating tissue comprising the steps of providing a probe including a body having a distal tip, a position sensor for determining a position of the distal tip and a hollow needle movable from the distal tip of the body. The probe is brought into contact with a tissue portion and the hollow needle is moved out of the distal tip of the body and into the tissue portion whereby a therapeutic agent is injected into the tissue portion through the hollow needle.

Claims

1. A method for treating tissue comprising the steps of:

providing a probe including a body having a proximal end and a distal end, said probe also including a position sensor for determining an instantaneous position and an orientation of said distal end of said body, and a hollow needle movable from said distal end of said body;

navigating said probe to a tissue portion using said position sensor of said probe;

sensing the instantaneous position and orientation of said distal end of said body using said position sensor;

bringing said distal end of said probe into contact with said tissue portion based on the position and orientation of said distal end of said body using said position sensor of said probe;

moving said hollow needle out of said distal end of said body and into said tissue portion;

injecting a therapeutic agent into said tissue portion through said hollow needle; and

urging said hollow needle back into said distal end of said body after injecting said therapeutic agent into said tissue portion.

2. The method according to claim 1, including performing functional mapping of said tissue portion.

3. The method according to claim 2, including performing said functional mapping and said injecting during the same procedure.

4. The method according to claim 1, including determining the position of said distal end of said body by receiving a generated field with said position sensor.

5. The method according to claim 4, including generating said generated field with a transmitter.

6. The method according to claim 5, wherein generating said generated field with a transmitter includes generating an AC magnetic field with said transmitter.

7. The method according to claim 1, further comprising determining the instantaneous position and the orientation including pitch of said distal end of said body of said probe.

8. The method according to claim 7, further comprising determining the instantaneous position and the orientation including yaw of said distal end of said body of said probe.

9. The method according to claim 8, further comprising determining the instantaneous position and the orientation including roll of said distal end of said body of said probe.

10. The method according to claim 7, further comprising determining when said probe is not in motion when said probe is in contact with said tissue portion using said position sensor.

11. The method according to claim 8, further comprising determining when said probe is not in motion when said probe is in contact with said tissue portion using said position sensor.

12. The method according to claim 9, further comprising determining when said probe is not in motion when said probe is in contact with said tissue portion using said position sensor.