Bioabsorbable sealant

• US 6,592,608 B2
• Filed: 12/07/2001
• Issued: 07/15/2003
• Est. Priority Date: 12/07/2001
• Status: Expired due to Term

• Current Assignee: Merit Medical Systems, Inc.
• Original Assignee: Biopsy Sciences LLC
• Inventors: Hronowski, Lucjan J. J., Fisher, John S., Ahari, Frederick
• Primary Examiner(s): Milano, Michael J.
• Assistant Examiner(s): ROBERTS, PAUL A
• Application Number:
  US09/683,282
• Publication Number:
  US 20030109899A1
• Time in Patent Office: 585 Days
• Field of Search: 606/213, 606/214, 606/230, 604/197, 604/187, 528/354, 528/408, 525/411, 424/443, 404/444
• US Class Current: 606/213
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 17/064 Surgical staples, i.e. penetrating the tissue
• CPC Class Codes: A61B 17/0644 penetrating the tissue, deformable to closed position
• CPC Class Codes: A61B 2017/00004 (bio)absorbable, (bio)resorbable or resorptive
• CPC Class Codes: A61B 2017/00575 for closure at remote site, e.g. closing atrial septum defects
• CPC Class Codes: A61B 2017/00601 Implements entirely comprised between the two sides of the opening
• CPC Class Codes: A61P 9/00 Drugs for disorders of the cardiovascular system

Abstract

Openings in a mammalian body made by any medical procedure or non-medical event are sealed with a bioabsorbable plug or sewn with a bioabsorbable suture. In one exemplary embodiment, the plug in dehydrated, unexpanded condition is pushed by a pushing device through the lumen of a needle until a first part of the plug is external to the opening and a second part is internal to the opening. The needle is then withdrawn while the position of the pushing device is maintained. The pushing device is then withdrawn, leaving the plug in sealing relation to the opening. The body'"'"'s moisture causes the plug to expand to complete the sealing of the opening, or the expansion may be caused by exposure to air, light, or other stimulant. The opening may be formed in soft tissue, internal organs, or hard tissue. The plug seals the flow of liquid or gaseous biological fluids.

Claims

1. A method for sealing a puncture opening of the type made by a coaxial needle, comprising the steps of:

providing a dehydrated plug formed of hydrogel that expands in response to application of a liquid fluid thereto;

slidingly disposing the dehydrated plug in a lumen of said coaxial needle;

pre-hydrating said dehydrated plug by introducing a liquid-fluid solution into said lumen of said coaxial needle before displacing said prehydrated plug from said lumen;

slidingly displacing said prehydrated plug within said lumen to a preselected location near a distal end of said lumen;

withdrawing said coaxial needle while maintaining said prehydrated plug at said preselected location;

whereby said pre-hydrated plug expands to fill said puncture opening in less time than a dehydrated plug that is not pre-hydrated.