Methods of skin rejuvenation using high intensity focused ultrasound to form an ablated tissue area containing a plurality of lesions

• US 6,595,934 B1
• Filed: 07/31/2000
• Issued: 07/22/2003
• Est. Priority Date: 01/19/2000
• Status: Expired due to Term

• Current Assignee: Medtronic Xomed Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Xomed Incorporated (Medtronic Plc)
• Inventors: Hissong, James B., Dinger, Fred B.
• Primary Examiner(s): Smith, Ruth S.
• Application Number:
  US09/629,194
• Time in Patent Office: 1,086 Days
• Field of Search: 601/2-4, 600/439, 607/50, 606/31, 606/28
• US Class Current: 601/3
• CPC Class Codes: A61B 2017/00761 Removing layer of skin tissue, e.g. wrinkles, scars or cancerous tissue
• CPC Class Codes: A61N 2007/0034 Skin treatment
• CPC Class Codes: A61N 2007/0065 Concave transducers
• CPC Class Codes: A61N 2007/0078 with multiple treatment transducers
• CPC Class Codes: A61N 2007/027 with multiple foci created simultaneously
• CPC Class Codes: A61N 7/02 Localised ultrasound hyperthermia hyperthermia in general A61F7/00

Abstract

A method of skin rejuvenation by thermal ablation using high intensity focused ultrasound energy includes the steps of positioning an ultrasound emitting member adjacent an external surface of the skin, emitting ultrasound energy from the ultrasound emitting member into the skin, focusing the ultrasound energy in the skin, ablating the skin with the focused ultrasound energy to form an ablated tissue area below the external surface of the skin containing unablated tissue of the skin and a plurality of lesions at which the tissue of the skin is ablated, and removing the ultrasound emitting member from adjacent the external surface of the skin. The lesions cause collagen production by the skin to be stimulated. The lesions can begin and end at predetermined depths beneath the external surface of the skin so that the epidermis and the deep layer of the dermis are not damaged.

Claims

1. A method of skin rejuvenation comprising the steps of

positioning an ultrasound emitting member adjacent an external tissue surface of the skin of a patient;

emitting ultrasound energy from the ultrasound emitting member into the skin;

focusing the ultrasound energy simultaneously at a plurality of spaced focusing zones contained in a target area in the skin;

heating the skin at the focusing zones with the focused ultrasound energy to form an ablated tissue area at the target area containing unablated tissue of the skin and a plurality of lesions at the focusing zones, respectively, at which the tissue of the skin is ablated; and

removing the ultrasound emitting member from adjacent the external surface of the skin.

2. The method of skin rejuvenation as recited in claim 1 wherein said step of focusing includes focusing the ultrasound energy in a target area disposed beneath the external surface of the skin.

3. The method of skin rejuvenation as recited in claim 2 wherein said step of heating includes heating the skin at the focusing zones with the focused ultrasound energy to achieve a temperature in the range of 60 to 90 degrees Celsius.

4. The method of skin rejuvenation as recited in claim 3 wherein said step of heating includes heating the skin at the focusing zones with the focused ultrasound energy so that the lesions begin at a beginning margin located below the epidermis of the skin.

5. The method of skin rejuvenation as recited in claim 4 wherein said step of heating includes heating the skin at the focusing zones with the focused ultrasound energy so that the lesions end at an ending margin located above the deep dermis of the skin.

6. The method of skin rejuvenation as recited in claim 5 wherein said step of heating includes heating the skin at the focusing zones with the focused ultrasound energy for a duration in the range of 2 to 60 seconds.

7. The method of skin rejuvenation as recited in claim 1 wherein said step of heating includes forming the ablated tissue area surrounded by unablated tissue of the skin.

8. The method of skin rejuvenation as recited in claim 7 wherein said step of heating includes forming the ablated tissue area so that the plurality of lesions do not contact one another.

9. The method of skin rejuvenation as recited in claim 7 wherein said step of heating includes forming the ablated tissue area so that at least one of the plurality of lesions contacts another of the plurality of lesions.

10. A method of skin rejuvenation comprising the steps of

positioning an ultrasound emitting member adjacent an external surface of the skin;

emitting ultrasound energy simultaneously from a plurality of ultrasound emitting elements of the ultrasound emitting member;

focusing the ultrasound energy in the skin below the external surface of the skin at a plurality of spaced focusing zones corresponding to the ultrasound emitting elements, respectively, while the ultrasound emitting member is maintained in one place adjacent the external surface of the skin;

ablating the skin with the focused ultrasound energy to form an ablated tissue area below the external surface of the skin containing unablated tissue of the skin and a plurality of lesions at the focusing zones, respectively, at which the tissue of the skin is ablated, the reaction to which is production of collagen by the dermis; and

removing the ultrasound emitting member from adjacent the external surface of the skin.

11. The method of skin rejuvenation as recited in claim 10 wherein said step of ablating includes forming the plurality of lesions to begin at a beginning margin located 50 to 100 micrometers below the external surface of the skin.

12. The method of skin rejuvenation as recited in claim 11 wherein said step of ablating includes forming the plurality of lesions to have a depth of 50 to 150 micrometers.

13. The method of skin rejuvenation as recited in claim 12 wherein said step of ablating includes forming the ablated tissue area to have a cross-sectional length of 3 to 50 mm and a cross-sectional width of 3 to 50 mm.

14. The method of skin rejuvenation as recited in claim 10 wherein said step of focusing includes focusing the ultrasound energy in the superficial dermis of the skin.

15. A method of skin rejuvenation comprising the steps of

positioning an ultrasound emitting member adjacent an external surface of the skin of a patient;

actuating selected ones of a plurality of ultrasound emitting elements of the ultrasound emitting member to emit ultrasound energy;

simultaneously emitting ultrasound energy from the selected ultrasound emitting elements into the skin;

focusing the ultrasound energy in the skin below the epidermis simultaneously at a plurality of spaced focusing zones corresponding to the selected ultrasound emitting elements, respectively;

ablating the skin with the focused ultrasound energy to form an ablated tissue area below the epidermis containing unablated tissue of the skin and a plurality of lesions at the focusing zones, respectively, at which the tissue of the skin is ablated; and

removing the ultrasound emitting member from adjacent the external surface of the skin.

16. The method of skin rejuvenation as recited in claim 15 and further including, prior to said step of actuating, the step of selecting the ultrasound emitting elements to be actuated in accordance with a desired surface pattern for the plurality of lesions.

17. The method of skin rejuvenation as recited in claim 16 wherein said step of ablating includes forming the ablated tissue area between the epidermis and deep dermis of the skin.

18. The method of skin rejuvenation as recited in claim 15 and further including, subsequent to said step of removing, the step of allowing the plurality of lesions to be assimilated by the patient'"'"'s body whereby the production of collagen by the skin is increased in the ablated tissue area.