Artificial olfactory system

• US 6,598,459 B1
• Filed: 01/02/1999
• Issued: 07/29/2003
• Est. Priority Date: 01/09/1998
• Status: Expired due to Fees

• Current Assignee: Chi Yung Fu
• Original Assignee: Chi Yung Fu
• Inventors: Fu, Chi Yung
• Primary Examiner(s): Lefkowitz, Edward
• Assistant Examiner(s): CYGAN, MICHAEL T
• Application Number:
  US09/223,831
• Time in Patent Office: 1,669 Days
• Field of Search: 73/232, 73/233.4, 73/240.6, 73/310.2, 73/310.5, 73/310.6, 422/90
• US Class Current: 73/23.34
• CPC Class Codes: G01N 33/0031 comprising two or more sensors, e.g. a sensor array electrochemical electrode arrays G01N27/27
• CPC Class Codes: Y10S 977/957 Of chemical property or presence

Abstract

The artificial olfactory system is an ultra-sensitive and selective odor sensing system for the detection of odorant molecules down to the part per trillion level. The system includes multiple ultra sensitive frequency sensors, such as sensors based on piezoelectric substrates or micro-machined resonators, capable of detecting frequency changes resulting from the interaction of odorant molecules with the sensor. A coating applied to the sensor greatly increases the surface of interaction between the odorant molecules or biological agents and the sensor. An array of these sensors, each responding to the interaction of an odorant molecule species but in a different manner, results in different frequency shifts. An ultra sensitive frequency measurement device measures as small as part per billion shift in frequency. An intelligent processor based on artificial neural networks and other intelligent signal processing system detects, recognizes, and generalizes the signature resulting from the collective response of all the sensors.

Claims

1. A sensor element for an artificial olfactory system, comprising:

a sensor substrate;

a layer of surface area increasing material on a surface of the substrate;

a coating of odorant molecule attachment material on the layer of surface area increasing material;

wherein the surface area increasing material is an aerogel, a porous carbon, or a nanotube.

2. The sensor element of claim 1 wherein the odorant molecule attachment material is a polymer.

3. The sensor element of claim 1 wherein the odorant molecule attachment material is a radiation treated material.

4. The sensor element of claim 1 wherein the sensor substrate is a resonator.

5. The sensor element of claim 1 wherein the sensor substrate is a piezoelectric crystal, a surface acoustic wave (SAW) device, or a micro-machined resonator.

6. The sensor element of claim 1 wherein the odorant molecule attachment material is a virus attachment material.

7. The sensor element of claim 1 wherein the odorant molecule attachment material is an antibody, a protein, or a cell membrane.

8. The sensor element of claim 1 further comprising a reactive material operatively associated with the sensor substrate for reacting with a substance to be detected to produce detectable odorant molecules.

9. An artificial olfactory system, comprising:

a plurality of sensor elements, each comprising a sensor substrate, a layer of surface area increasing material on a surface of the substrate, a coating of odorant molecule attachment material on the layer of surface area increasing material, wherein the surface area increasing material is an aerogel, a porous carbon, or a nanotube;

a measurement device connected to the plurality of sensor elements to detect changes produced by the presence of odorant molecules;

a signal processor connected to the measurement device.

10. The artificial olfactory system of claim 9 wherein the measurement device is a frequency shift detector which detects changes in the resonant frequency of each sensor element.

11. The artificial olfactory system of claim 9 wherein the signal processor is an artificial neural network.

12. The artificial olfactory system of claim 9 wherein the odorant molecule attachment material is a polymer.

13. The artificial olfactory system of claim 9 wherein the odorant molecule attachment material is a radiation treated material.

14. The artificial olfactory system of claim 9 wherein the odorant molecule attachment material is a virus attachment material.

15. The artificial olfactory system of claim 9 wherein the odorant molecule attachment material is an antibody, a protein, or a cell membrane.

16. The artificial olfactory system of claim 9 further comprising a reactive material operatively associated with the sensor substrate for reacting with a substance to be detected to produce detectable odorant molecules.