Cell delivery catheter and method

• US 6,599,274 B1
• Filed: 05/19/2000
• Issued: 07/29/2003
• Est. Priority Date: 01/20/2000
• Status: Expired due to Fees

• Current Assignee: University of Virginia Patent Foundation (University of Virginia)
• Original Assignee: George T. Gillies, Helen L. Fillmore, John Kucharczyk, William C. Broaddus
• Inventors: Kucharczyk, John, Gillies, George T., Broaddus, William C., Fillmore, Helen L.
• Primary Examiner(s): Buiz, Michael Powell
• Assistant Examiner(s): NGUYEN, TUAN N
• Application Number:
  US09/574,857
• Time in Patent Office: 1,166 Days
• Field of Search: 604/27, 604/28, 604/48, 604/500, 604/522, 604/57, 604/59-62, 604/64, 604/68, 604/70, 604/72, 604/158-160, 604/93.01, 604/95.01, 604/95.02, 604/164.01, 604/164.02, 604/164.13, 604/170.01, 604/170.02, 604/264, 604/266, 606/13-15
• US Class Current: 604/264
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector
• CPC Class Codes: A61M 25/10 Balloon catheters A61M25/0125 takes precedence; embolectomy A61B17/22032; retractors A61B17/02; inflatable balloons for placing stents or stent-grafts A61F2/958 ; stomach balloons for treatment of obesity A61F5/0003; oesophagal tubes A61J15/00

Abstract

A cell delivery catheter having one of more apearutres is used to positon and deliver cells to an implant site in a patient.

Claims

1. A cell delivery catheter system for delivering and positioning cells in a patient'"'"'s body operable by a user comprising:

a catheter body having a proximal end and a distal end, said catheter body defining a central axis;

said catheter body fixed with respect to said patient body such that the catheter cannot move during use, said catheter body having at least one aperture located orthogonal to said central axis;

said aperture being elongate along said axis to define a plurality of delivery locations;

a cell delivery barrel located within said catheter body having a distal aperture, said cell delivery barrel adapted to hold cells;

said cell delivery barrel having at least one aperture orthogonal to said central axis, and movable with respect to said fixed catheter body to selectively align with said catheter body to control the delivery rate and delivery location of said cells at one of several locations along the central axis;

a source of fluid coupled to said cell delivery barrel for ejecting said cells from said cell delivery barrel under the control of a user.

2. The cell delivery catheter system of claim 1 wherein extension of the cell delivery barrel determines the location of cell delivery and the angular rotation of the cell delivery barrel determines the aperture size and therefore the delivery rate when said source of fluid is a manually operated syringe controlled by said user.

3. The cell delivery catheter system of claim 1 wherein extension of the cell delivery barrel determines the location of cell delivery and the angular rotation of the cell delivery barrel determines the aperture size and where said source of fluid is a motorized syringe controlled by said user.