Method and apparatus for measuring values of physiological parameters

• US 6,602,199 B2
• Filed: 11/19/2001
• Issued: 08/05/2003
• Est. Priority Date: 06/09/1999
• Status: Expired due to Term

• Current Assignee: VSM Medtech Devices Inc.
• Original Assignee: VSM Technology Inc.
• Inventors: Waterman, David Sholom, Gelfer, Mark Elliot, Christensen, Paul Richard, Chen, Yunquan, Zorn, Anton Bogdan, Strange, Kevin Daryl
• Primary Examiner(s): Nasser, Robert L.
• Application Number:
  US09/988,110
• Publication Number:
  US 20020035332A1
• Time in Patent Office: 624 Days
• Field of Search: 600/485, 600/490, 600/493-6, 600/500-503, 600/579, 600/561, 600/300
• US Class Current: 600/485
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/022 by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers

Abstract

Apparatus for measuring a physiological parameter of a patient, such as blood pressure, takes a sequence consisting of a predetermined number of individual measurements. The apparatus computes a best estimate of the physiological parameter from values obtained in two or more of the measurements. The apparatus automatically takes a sequence of measurements and then stops. The apparatus can operate unattended so that it is not necessary for a physician or other health care worker to be present while measurements are being made. The use of the invention to measure blood pressure of a patient reduces the effect of “white coat” hypertension on the best estimate. Preferred embodiments of the apparatus ignore results of a first measurement in the sequence. The patient is already familiar with the apparatus when subsequent measurements are taken. This further reduces the possibility that the patient'"'"'s reaction to the process of measurement will affect the results of the measurement.

Claims

1. A method for measuring a blood pressure of a subject, the method comprising:

under automatic control, performing a sequence of four or more measurements of the subject'"'"'s blood pressure at spaced apart times to obtain four or more measured values for the blood pressure; and

,

computing an estimate of the blood pressure from two or more of the measured values without using an initial group of two or more of the measured values in computing the estimate.

2. The method of claim 1 wherein obtaining each measured value for the blood pressure comprises inflating a cuff surrounding a limb of the subject.

3. The method of claim 2 wherein obtaining a measured value for the blood pressure comprises measuring a pressure in the cuff and using an oscillometric technique to compute blood pressure from the measured pressure in the cuff.

4. The method of claim 1 wherein the sequence consists of from 5 to 7 measurements of the subject'"'"'s blood pressure.

5. The method of claim 1 comprising receiving user input specifying a user-specified number of measurements to be taken in the sequence wherein performing a sequence of four or more measurements of the subject'"'"'s blood pressure comprises performing the user-specified number of measurements.

6. The method of claim 4 comprising providing a time interval in the range of 1 minute to 5 minutes between the starts of successive blood pressure measurements in the sequence.

7. The method of claim 1 comprising providing a time interval in the range of 1 minute to 5 minutes between the starts of successive blood pressure measurements in the sequence.

8. The method of claim 1 comprising, before performing the sequence of measurements, accepting a user input specifying a time interval between the starts of successive blood pressure measurements in the sequence wherein performing the sequence of measurements comprises providing the user-specified time interval between the starts of successive blood pressure measurements in the sequence.

9. The method of claim 1 wherein computing an estimate of the blood pressure from two or more of the measured values comprises excluding measured values which fail to satisfy an acceptance criterion.

10. The method of claim 1 wherein performing the sequence of measurements comprises comparing a number of completed measurements to a number of measurements specified by a user and the method continues performing the sequence of measurements while the number of completed measurements is less than the number of measurements specified by the user.

11. The method of claim 10 wherein the number of measurements specified by the user exceeds 4.

12. The method of claim 11 wherein the number of measurements specified by the user is in the range of 5 to 7.

13. A method for measuring a blood pressure of a subject, the method comprising:

under automatic control, performing a sequence comprising a number of cycles at spaced apart times, each cycle comprising one or more physical actions and, during at least two of the cycles, recording measured values of the subject'"'"'s blood pressure;

computing an estimate of the blood pressure from two or more of the measured values without using any measured values obtained during an initial one or more of the cycles in computing the estimate.

14. The method of claim 13 wherein the physical actions comprise inflating and deflating an inflatable member.

15. The method of claim 14 wherein the inflatable member comprises a cuff on a limb of the subject.

16. The method of claim 14 wherein recording measured values of the subject'"'"'s blood pressure comprises making an oscillometric measurement of the subject'"'"'s blood pressure.

17. The method of claim 16 wherein the inflatable member comprises a cuff on a limb of the subject and the physical actions comprise inflating and deflating the cuff.

18. The method of claim 17 wherein the number of cycles is predetermined.

19. The method of claim 16 wherein computing the estimate of the subject'"'"'s blood pressure is performed without using any measured values obtained during an initial group of two or more of the cycles.

20. The method of claim 16 wherein calculating the estimate of the subject'"'"'s blood pressure comprises computing an average of a plurality of the two or more of the measured values.

21. The method of claim 16 wherein calculating the estimate of the subject'"'"'s blood pressure comprises computing a weighted average of a plurality of the two or more of the measured values.

22. The method of claim 21 comprising weighting more recently obtained ones of the plurality of the two or more of the measured values more heavily than less recently obtained ones of the plurality of the two or more of the measured values.

23. The method of claim 16 wherein calculating the estimate of the subject'"'"'s blood pressure comprises computing a median of a plurality of the two or more of the measured values.

24. The method of claim 16 comprising providing a time interval in the range of 1 minute to 5 minutes between the starts of successive cycles in the sequence of cycles.

25. The method of claim 16 wherein the sequence consists of from 5 to 7 measurements of the subject'"'"'s blood pressure.

26. The method of claim 13 wherein the method comprises

receiving a user input and determining a total number of cycles from the user input;

comparing a number of completed cycles to the total number of cycles; and

,

continuing to perform the sequence while the number of completed cycles is less than the total number of cycles.

27. The method of claim 13 wherein computing the estimate of the subject'"'"'s blood pressure is performed without using any measured values obtained during an initial group of two or more of the cycles.

28. The method of claim 13 comprising, before performing the sequence of cycles, receiving user input specifying a user-specified number of cycles to perform wherein performing the sequence of cycles comprises performing the user-specified number of cycles.

29. The method of claim 13 comprising providing a time interval in the range of 1 minute to 5 minutes between the starts of successive cycles in the sequence of cycles.

30. The method of claim 13 comprising, before performing the sequence of cycles, accepting a user input specifying a time interval between the starts of successive cycles in the sequence wherein performing the sequence of cycles comprises providing the user specified time interval between the starts of successive cycles in the sequence.

31. The method of claim 13 comprising leaving the subject alone in a room while the blood pressure measurement device is performing the sequence of cycles.

32. The method of claim 13 wherein calculating the estimate of the subject'"'"'s blood pressure comprises computing an average of a plurality of the two or more of the measured values.

33. The method of claim 13 wherein calculating the estimate of the subject'"'"'s blood pressure comprises computing a weighted average of a plurality of the two or more of the measured values.

34. The method of claim 15 comprising weighting more recently obtained ones of the plurality of the two or more of the measured values more heavily than less recently obtained ones of the plurality of the two or more of the measured values.

35. The method of claim 13 wherein calculating the estimate of the subject'"'"'s blood pressure comprises computing a median of a plurality of the two or more of the measured values.

36. The method of claim 13 wherein computing the estimate of the blood pressure from two or more of the measured values comprises excluding measured values which fail to satisfy an acceptance criterion.

37. The method of claim 13 comprising sounding an audible signal upon completion of the sequence.

38. A method for obtaining a measurement of a subject'"'"'s blood pressure, the method comprising:

providing a blood pressure measurement device comprising an inflatable member;

placing the inflatable member on a limb of the subject;

causing the blood pressure measurement device to perform a sequence of a number of cycles, the sequence including an initial cycle and a plurality of additional cycles, each of the cycles comprising inflating and deflating the inflatable member and during at least a plurality of the additional cycles recording measurements of the subject'"'"'s blood pressure;

computing an estimate of the subject'"'"'s blood pressure from a plurality of the recorded measurements wherein the plurality of measurements does not include a measurement obtained in the initial cycle; and

,

performing one or both of displaying the estimate on a display and recording the estimate.

39. The method of claim 38 wherein the inflatable member comprises an inflatable cuff and placing the inflatable member on a limb of the subject comprises surrounding a limb of the subject with the inflatable cuff.

40. The method of claim 38 wherein the plurality of measurements used in computing the estimate of the subject'"'"'s blood pressure does not include measurements obtained in an initial group of one or more of the additional cycles.

41. The method of claim 38 comprising leaving the subject alone in a room while the blood pressure measurement device is performing the sequence of cycles.

42. The method of claim 38 wherein calculating the estimate of the subject'"'"'s blood pressure comprises computing an average of a plurality of the recorded measurements.

43. The method of claim 38 wherein calculating the estimate of the subject'"'"'s blood pressure comprises computing a weighted average of a plurality of the recorded measurements.

44. The method of claim 43 comprising weighting more recently obtained ones of the plurality of recorded measurements more heavily than less recently obtained ones of the plurality of recorded measurements.

45. The method of claim 38 wherein calculating the estimate of the subject'"'"'s blood pressure comprises computing a median of a plurality of the recorded measurements.

46. The method of claim 38 wherein recording measurements of the subject'"'"'s blood pressure comprises using an oscillometric method to obtain values representing the subject'"'"'s blood pressure and recording the values.

47. The method of claim 38 wherein the sequence consists of from 5 to 7 cycles.

48. The method of claim 47 wherein there is a time interval in the range of 1 minute to 5 minutes between the starts of successive cycles in the sequence.

49. The method of claim 38 wherein there is a time interval in the range of 1 minute to 5 minutes between the starts of successive cycles in the sequence.

50. The method of claim 38 comprising, before causing the blood pressure measurement device to perform a sequence of a predetermined number of cycles, receiving user input specifying the predetermined number of cycles.

51. The method of claim 50 wherein the sequence consists of more than 5 cycles.

52. The method of claim 38 wherein the method comprises:

receiving a user input and determining a total number of cycles from the user input;

comparing a number of completed cycles to the total number of cycles; and

,

continuing to perform the sequence while the number of completed cycles is less than the total number of cycles.

53. The method of claim 38 comprising, after the sequence of cycles has been completed, displaying each of the recorded measurements.

54. The method of claim 38 comprising:

before causing the blood pressure measurement device to perform a sequence of a predetermined number of cycles, receiving user input specifying a time period

wherein causing the blood pressure measurement device to perform a sequence of a predetermined number of cycles comprises causing start times of successive ones of the cycles to be spaced apart by the time period.

55. The method of claim 38 comprising:

receiving a user input and obtaining a desired time between cycles from the user input; and

,

initiating an additional cycle when a time since a previous cycle is equal to the desired time between cycles.

56. The method of claim 38 wherein the sequence consists of more than 5 cycles.

57. The method of claim 38 wherein:

recording measurements of the subject'"'"'s blood pressure comprises recording measured values of each of the subject'"'"'s systolic blood pressure and diastolic blood pressure;

computing the estimate of the subject'"'"'s blood pressure comprises computing estimates of the subject'"'"'s systolic and diastolic blood pressures; and

the method comprises;

displaying the estimates of the subject'"'"'s systolic and diastolic blood pressures on a display.

58. An apparatus for measuring a physiological parameter of a subject, the apparatus comprising:

a measuring means for measuring a value of a physiological parameter;

a controller connected to the measuring means, the controller adapted to cause the measuring means to make a sequence consisting of a number of measurements of the physiological parameter;

a memory for receiving and storing measured values of the physiological parameter;

calculation means for determining an estimate of the physiological parameter from a plurality of the measured values; and

,

a display for displaying the estimate;

wherein the controller comprises a timer and a counter, the timer configured to set a time between sequential measurements in the sequence, the counter counting the measurements made by the measuring means; and

,

wherein the calculation means calculates the estimate without reference to an initial two or more of the measured values measured by the measuring means.

59. The apparatus of claim 58 wherein the controller comprises a programmed microprocessor.

60. The apparatus of claim 58 wherein the measuring means comprises a blood pressure measuring means and the physiological parameter measured comprises a blood pressure of a subject.

61. The apparatus of claim 60 wherein the measuring means comprises an inflatable member and a pressure sensor for measuring a pressure within the inflatable member.

62. The apparatus of claim 61 wherein the inflatable member comprises an inflatable cuff.

63. The apparatus of claim 60 comprising a user input for receiving the number.

64. The apparatus of claim 60 comprising a user input for receiving a user-specified value wherein the apparatus comprises means for setting the time between sequential measurements in response to the user-specified value.

65. The apparatus of claim 58 wherein the controller comprises means for rejecting measurements made by the measuring means which fail to satisfy an acceptance criterion.

66. The apparatus of claim 59 comprising a program memory holding instructions which, when executed by the microprocessor, cause the microprocessor to:

receive a user input and determine a total number of cycles from the user input;

compare a number of completed cycles to the total number of cycles; and

,

continue to perform the sequence while the number of completed cycles is less than the total number of cycles.

67. The apparatus of claim 59 comprising a program memory comprising instructions which, when executed on the microprocessor, causes the microprocessor to receive a user input and obtain a desired time between cycles from the user input;

and,

initiate an additional cycle when a time since a previous cycle is equal to the desired time between cycles.

68. The apparatus of claim 58 comprising a user control input connected to the controller, wherein the controller terminates performing the sequence of cycles upon operation of the user control input.

69. The apparatus of claim 58 wherein the controller is configured to display the value of the counter on the display while the controller is causing the measuring means to make a sequence consisting of a number of measurements of the physiological parameter.

70. An apparatus for measuring a blood pressure of a subject, the apparatus comprising:

an inflatable member;

a pump connected to pressurize the inflatable member;

a valve connected to vent the inflatable member;

a pressure sensor connected to detect a pressure within the inflatable member;

a controller connected to the pump and valve, the controller configured to perform a sequence of a predetermined number of cycles, the sequence including an initial cycle and a plurality of additional cycles, each of the cycles comprising operating the pump to inflate the inflatable member and operating the valve to deflate the inflatable member;

a measurement system connected to receive a signal from the pressure sensor, the measurement system configured to compute a value for the subject'"'"'s blood pressure based upon the signal from the pressure sensor during at least a plurality of the cycles and to record the computed values of the subject'"'"'s blood pressure in a memory;

a calculation system for determining an estimate of the blood pressure from a plurality of the measured values, the plurality of measured values corresponding to cycles which do not include the initial cycle; and

,

a display for displaying the estimate.

71. The apparatus of claim 70 wherein the calculation system is configured to determine the estimate of the blood pressure from a plurality of the measured values, the plurality of measured values all corresponding to cycles other than cycles of an initial group of two or more of the cycles.

72. The apparatus of claim 70 comprising a review control, wherein the controller is configured to display the measured values on the display in response to operation of the review control.

74. The program memory of claim 72 wherein the sequence comprises at least four blood pressure measurements and the instructions cause the processor to compute the estimate without using an initial group of two or more of the measured values.

73. A program memory containing a software program the software program comprising instructions which, if executed by a processor in a blood pressure measurement device comprising a display and a blood pressure measurement subsystem, cause the processor to:

control the blood pressure measurement subsystem to take a sequence comprising at least three blood pressure measurements, taken at spaced apart times, to obtain three or more measured values for the blood pressure;

compute an estimate of the blood pressure from two or more of the measured values without using an initial group of one or more of the measured values in computing the estimate; and

,

display the estimate on the display.

75. A program memory containing a software program the software program comprising instructions which, if executed by a processor in a blood pressure measurement device comprising a display and a blood pressure measurement subsystem, cause the processor to:

control the blood pressure measurement subsystem to perform a sequence comprising a number of cycles at spaced apart times, each cycle comprising one or more physical actions and, during at least two of the cycles, recording measured values of the subject'"'"'s blood pressure;

compute an estimate of the blood pressure from two or more of the measured values without using any measured values obtained during an initial one or more of the cycles in computing the best estimate; and

,

display the estimate on the display.