Device and methods for occlusion of the uterine artieries

• US 6,602,251 B2
• Filed: 04/17/2001
• Issued: 08/05/2003
• Est. Priority Date: 12/08/1998
• Status: Expired due to Fees

• Current Assignee: Vascular Control Systems, Inc. (Johnson & Johnson)
• Original Assignee: Vascular Control Systems, Inc. (Johnson & Johnson)
• Inventors: Jones, Michael, Lubock, Paul, Burbank, Fred
• Primary Examiner(s): Dvorak, Linda C. M.
• Assistant Examiner(s): Ruddy, David M.
• Application Number:
  US09/835,402
• Publication Number:
  US 20010014805A1
• Time in Patent Office: 840 Days
• Field of Search: 606/41-50, 606/194, 606/200, 128/830-831, 128/898, 600/376, 600/461
• US Class Current: 606/45
• CPC Class Codes: A61B 17/12013 for use in minimally invasive surgery, e.g. endoscopic surgery
• CPC Class Codes: A61B 17/42 Gynaecological or obstetrical instruments or methods ligaturing clamps or clips for the umbilical cord A61B17/122; curettage A61B17/320708; dilators A61M29/00
• CPC Class Codes: A61B 18/1485 having a short rigid shaft for accessing the inner body through natural openings
• CPC Class Codes: A61B 8/06 Measuring blood flow measuring volume flow in general G01F, e.g. G01F1/66, G01F1/72; measuring speed of fluids in general G01P5/00
• CPC Class Codes: A61B 8/0833 involving detecting or locating foreign bodies or organic structures
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00

Abstract

Devices and methods are disclosed for treating a uterine disorder which receive its blood supply from a uterine artery. In particular, uterine fibroids are effectively treated by occluding the uterine arteries using trans-vaginal, trans-uterine, transrectal, or retroperitoneal approaches. The devices and methods are advantageous because the inventive procedures may be performed by a patient'"'"'s gynecologist in the course of treatment, avoiding the need for referrals to specialist practitioners and for more radical treatments, such as hysterectomies. The methods include both temporary and permanent occlusion of the arteries. A cannula carries an imaging device and a member which will easily penetrate tissue, the member including a device which partially or completely, and temporarily or permanently, occludes a uterine artery.

Claims

1. A method of treating a female patient'"'"'s uterus, comprising:

providing an occluding system having a pressure applying mechanism configured to compress a blood vessel and a blood vessel sensor;

inserting the occluding system into the female patient to access a region adjacent a uterine artery leading to the patient'"'"'s uterus;

locating the uterine artery with the blood vessel sensor; and

occluding the located uterine artery by compressing the located uterine artery with the pressure-applying mechanism of said occluding system to at least partially cut off blood flow through the located uterine artery to the patient'"'"'s uterus.

2. The method of claim 1, wherein the occluding system penetrates tissue to access a region adjacent a uterine artery.

3. The method of claim 2, wherein the tissue penetrated by the occluding system includes abdominal tissue.

4. The method of claim 1, wherein the occluding system is inserted into a body cavity of the patient.

5. The method of claim 4, wherein said body cavity is a vagina.

6. The method of claim 4, wherein said body cavity is a uterus.

7. The method of claim 4, wherein said body cavity is a rectum.

8. The method of claim 4, wherein said body cavity is a peritoneal cavity.

9. The method of claim 1, wherein the occluding system accesses an anatomical region adjacent to the uterine artery and an ultrasonic transducer senses the location of anatomical structures in a sensing plane.

10. A method of treating a female patient in accordance with claim 1, wherein said female patient has a uterine fibroid.

11. A method of claim 1, wherein the uterine artery is located with a blood vessel sensor selected from the group consisting of a CT scanner, a fluoroscope, X ray, a MRI device, Doppler audio device, a gray scale color 2D Doppler ultrasound device, a landmark system, and combinations thereof.

12. A method of claim 1, wherein the occluding system is inserted into a body cavity along a path selected from the group consisting of a path along a uterine wall, a path along a vaginal wall, a path along a rectal wall, a path through a uterine wall, a path through a vaginal wall, a path through a rectal wall, and a path into a peritoneal cavity.

13. A method of treating a female patient in accordance with claim 1, wherein said occluding said uterine artery comprises temporarily occluding said uterine artery.

14. A method of treating a female patient in accordance with claim 1, wherein occluding said uterine artery comprises permanently occluding said uterine artery.

15. A method of treating a female patient in accordance with claim 1, wherein occluding said uterine artery comprises completely occluding said uterine artery.

16. A method of claim 1, wherein the uterine artery is compressed with a pressure-applying mechanism selected from the group consisting of a pair of opposed jaws, a clip, a T-bar, a loop, a snare, a coil, a spring, a malecot, and a staple.

17. The method of claim 1, wherein the blood vessel sensor comprises a blood vessel locating device selected from the group consisting of an ultrasound imaging device, a Doppler ultrasound device, a landmarking system applied to a device, a computer-aided tomography (CAT) scanner, a fluoroscope, an angiography device, and a magnetic resonance imaging (MRI) device.

18. A method of treating a female patient'"'"'s uterus, comprising the steps of:

providing an occluding system having a pressure applying mechanism configured to compress a blood vessel and a blood vessel sensor;

inserting the occluding system into the female patient to access a region adjacent a uterine artery leading to the patient'"'"'s uterus;

locating the uterine artery with the blood vessel sensor; and

occluding the located uterine artery by compressing the located uterine artery with the pressure-applying mechanism of said occluding system to at least partially cut off the blood supply through the located uterine artery to the patient'"'"'s uterus.

19. A method of treating a female patient'"'"'s uterus, comprising:

providing an occluding system having a pair of opposed pressure applying jaws;

advancing the occluding system within the female patient to a region adjacent a uterine artery leading to the patient'"'"'s uterus;

locating the uterine artery with a blood vessel sensor; and

occluding the located uterine artery by at least partially closing the opposed pressure applying jaws of the occluding system against the located uterine artery to at least partially cut off the blood flow through the located uterine artery to the patient'"'"'s uterus.