Filamentous embolic device with expansile elements
First Claim
1. A vascular embolization device, comprising:
- an elongate, flexible, filamentous carrier; and
an embolizing element non-releasably fixed to the carrier, the embolizing element being formed from an expansile polymer that expands in response to a change in an environmental parameter selected from the group consisting of temperature and pH after a predetermined time interval.
1 Assignment
0 Petitions
Accused Products
Abstract
An embolization device includes one or more expansible, hydrophilic embolizing elements non-releasably carried along the length of a filamentous carrier that is preferably made of a very thin, highly flexible filament or microcoil of nickel/titanium alloy. At least one expansile embolizing element is non-releasably attached to the carrier. A first embodiment includes a plurality of embolizing elements fixed to the carrier at spaced-apart intervals along its length. In a second embodiment, an elongate, continuous, coaxial embolizing element is non-releasably fixed to the exterior surface of the carrier, extending along a substantial portion of the length of the carrier proximally from a distal tip. In either of the embodiments, the embolizing elements may be made of a hydrophilic, macroporous, polymeric, hydrogel foam material. In the second embodiment, the elongate embolizing element is preferably made of a porous, environmentally-sensitive, expansile hydrogel that expands, after a predetermined time delay, in response to a change in an environmental parameter, such as pH or temperature.
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Citations
34 Claims
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1. A vascular embolization device, comprising:
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an elongate, flexible, filamentous carrier; and
an embolizing element non-releasably fixed to the carrier, the embolizing element being formed from an expansile polymer that expands in response to a change in an environmental parameter selected from the group consisting of temperature and pH after a predetermined time interval. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A vascular embolization device, comprising:
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an elongate, flexible, filamentous carrier of predetermined length; and
a plurality of expansile fibers fixed to the carrier at spaced intervals along the length of the carrier, the fibers being formed from an expansile polymer hydrogel. - View Dependent Claims (9, 10, 11)
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12. A vascular embolization device, comprising:
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a flexible, filamentous carrier having an exterior surface and a distal tip; and
an expansile embolizing element non-releasably fixed coaxially to the exterior surface of the carrier at a location proximal from the distal tip, wherein the embolizing element is formed of an expansile, hydrophilic polymer that changes its physical character in response to a change in an environmental parameter selected from the group consisting of pH and temperature after a predetermined time interval. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19)
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20. A vascular embolization device that is deployable intravascularly while attached to a deployment instrument having a distal end, the embolization device comprising:
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a flexible filamentous carrier having proximal and distal ends;
an embolizing element coaxially covering a substantial portion of the length of the carrier between the proximal and distal ends thereof, the embolizing element being formed of an expansile hydrophilic polymer that expands in response to a change in an environmental parameter; and
a linkage element formed of an expansile hydrogel, located on the proximal end of the carrier, that releasably attaches the embolizatlon device to the distal end of the deployment instrument.
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21. A vascular embolization device that is deployable intravascularly while attached to a deployment instrument having a distal end, the embolization device comprising:
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a flexible filamentous carrier having proximal and distal ends;
an embolizing element coaxially covering a substantial portion of the length of the carrier between the proximal and distal ends thereof, the embolizing element being formed of a stretch-resistant, expansile hydrophilic polymer that expands in response to a change in an environmental parameter; and
a linkage element on the proximal end of the carrier that releasably attaches the embolization device to the distal end of the deployment instrument. - View Dependent Claims (22, 23, 24, 25, 26, 27)
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28. A vascular embolization device that is deployable intravascularly while attached to a deployment instrument having a distal end, the embolization device comprising:
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a flexible filamentous carrier having proximal and distal ends;
an embolizing element coaxially covering a substantial portion of the length of the carrier between the proximal and distal ends thereof, the embolizing element being formed of an expansile hydrophilic polymer that expands In response to a change in an environmental parameter selected from the group consisting of temperature and pH; and
a linkage element on the proximal end of the carrier that releasably attaches the embolization device to the distal end of the deployment instrument. - View Dependent Claims (29, 30, 31, 32, 33, 34)
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Specification