Human kinase proteins and polynucleotides encoding the same

• US 6,602,698 B2
• Filed: 12/07/2000
• Issued: 08/05/2003
• Est. Priority Date: 12/07/1999
• Status: Expired due to Fees

• Current Assignee: Lexicon Genetics, Incorporated
• Original Assignee: Lexicon Genetics, Incorporated
• Inventors: Sands, Arthur T., Zambrowicz, Brian, Scoville, John, Abuin, Alejandro, Friedrich, Glenn, Donoho, Gregory, Turner, C. Alexander Jr.
• Primary Examiner(s): MONSHIPOURI, MARYAM
• Application Number:
  US09/733,388
• Publication Number:
  US 20030064495A1
• Time in Patent Office: 971 Days
• Field of Search: 536/23.2, 435/194, 435/320.1, 435/325, 435/6, 435/252.3
• US Class Current: 435/252.3
• CPC Class Codes: A61K 38/00 Medicinal preparations containing peptides peptides containing beta-lactam rings A61K31/00; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, A61K31/00; ergot alkaloids of the cyclic peptide type A61K31/48; containing macromolecular compounds having statistically distributed amino acid units A61K31/74; medicinal preparations containing antigens or antibodies A61K39/00; medicinal preparations characterised by the non-active ingredients, e.g. peptides as drug carriers, A61K47/00
• CPC Class Codes: C12N 9/1205 Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases

Abstract

Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.

Claims

1. An isolated nucleic acid molecule comprising at least 24 contiguous bases of SEQ ID NO:

1.

2. An isolated nucleic acid molecule comprising a nucleotide sequence that:

(a) encodes the amino acid sequence shown in SEQ ID NO;

2; and

(b) hybridizes under highly stringent conditions including washing in 0.1×

SSC/0.1% SDS at 68°

C. to the complement of the nucleotide sequence of SEQ ID NO;

1.

3. An isolated nucleic acid molecule comprising a nucleotide sequence encoding the amino acid sequence shown in SEQ ID NO:

2.

5. An expression vector comprising a nucleic acid sequence of claim 3.

6. A cell comprising the expression vector of claim 5.

4. An isolated nucleic acid molecule comprising a nucleotide sequence encoding the amino acid sequence shown in SEQ ID NO:

4.

7. An expression vector comprising a nucleic acid sequence of claim 4.

8. A cell comprising the expression vector of claim 7.