Human adenylsuccinate synthetase and polynucleotides encoding the same
First Claim
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1. An isolated nucleic acid molecule comprising a nucleotide sequence that:
- (a) encodes the amino acid sequence shown in SEQ ID NO;
2;
or (b) hybridizes under stringent conditions to the nucleotide sequence of SEQ ID NO;
1 or the complement thereof wherein, the conditions are hybridization to filter-bound DNA in 0.5 M NaHPO4, 7% sodium dodecyl sulfate (SDS), 1 mM EDTA at 65°
C. and washing in 0.1×
SSC/0.1% SDS at 68°
C., wherein said nucleic acid has at least 85% identity with the nucleotide sequence of SEQ ID NO;
1, or the complement thereof, and encodes an adenylsuccinate synthethase.
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Abstract
Disclosed are a human polynucleotide and the encoded adenylsuccinate synthethase which, can be used in therapeutic, diagnostic, and pharmacogenomic applications.
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Citations
3 Claims
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1. An isolated nucleic acid molecule comprising a nucleotide sequence that:
-
(a) encodes the amino acid sequence shown in SEQ ID NO;
2;
or(b) hybridizes under stringent conditions to the nucleotide sequence of SEQ ID NO;
1 or the complement thereof wherein, the conditions are hybridization to filter-bound DNA in 0.5 M NaHPO4, 7% sodium dodecyl sulfate (SDS), 1 mM EDTA at 65°
C. and washing in 0.1×
SSC/0.1% SDS at 68°
C., wherein said nucleic acid has at least 85% identity with the nucleotide sequence of SEQ ID NO;
1, or the complement thereof, and encodes an adenylsuccinate synthethase.- View Dependent Claims (2)
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3. An isolated nucleic acid molecule encoding the amino acid sequence described in SEQ ID NO:
- 2.
Specification