PVC response-triggered blanking in a cardiac pacing system

• US 6,609,028 B2
• Filed: 04/26/2001
• Issued: 08/19/2003
• Est. Priority Date: 04/26/2001
• Status: Expired due to Fees

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Struble, Chester
• Primary Examiner(s): Schaetzle, Kennedy
• Application Number:
  US09/842,232
• Publication Number:
  US 20020183792A1
• Time in Patent Office: 845 Days
• Field of Search: 607/9, 607/14, 607/15
• US Class Current: 607/14
• CPC Class Codes: A61N 1/3622 comprising two or more electrodes co-operating with different heart regions
• CPC Class Codes: A61N 1/3684 for stimulating the heart at multiple sites of the ventricle or the atrium
• CPC Class Codes: A61N 1/36842 Multi-site stimulation in the same chamber
• CPC Class Codes: A61N 1/36843 Bi-ventricular stimulation

Abstract

A biventricular pacing system incorporates a premature ventricular contraction (PVC) response. The biventricular pacing system also includes a programmable ventricular blanking period (VBP) that is initiated with the PVC response. During the programmed VBP, ventricular events are effectively blanked out. This prevents both ventricular leads from each independently initiating a dual PVC response, based on the same PVC event.

Claims

1. An implantable cardiac pacemaker, comprising:

a first ventricular lead;

a second ventricular lead; and

a controller that controls the implantable cardiac pacemaker based in part on signals received from the first and second ventricular leads, and initiates an extended post ventricular atrial refractory period of between about 350-450 ms, during which sensed atrial events are ignored, and a programmable ventricular blanking period in response to a premature ventricular contraction.

2. The cardiac pacemaker of claim 1, wherein the post ventricular atrial refractory period is approximately equal to 400 ms.

3. The implantable cardiac pacemaker of claim 1, wherein the controller includes a microprocessor coupled to the first and second ventricular leads to sense the signals, and a microcomputer circuit coupled to the microprocessor that stores an algorithm that defines control parameters for the microprocessor, the control parameters controlling the response of the microprocessor to the premature ventricular contraction.

4. The implantable cardiac pacemaker of claim 1, wherein the ventricular blanking period has a length of time that corresponds to a length of time defined by an interventricular conduction delay.

5. The implantable cardiac pacemaker of claim 1, wherein the ventricular blanking period has a length of time that is approximately equal to a length of time defined by an interventricular conduction delay.

6. The implantable cardiac pacemaker of claim 5, wherein the interventricular conduction delay is between about 80-180 ms.

7. The implantable cardiac pacemaker of claim 1, wherein the ventricular blanking period has a length of time that is approximately equal to a length of time defined by an interventricular conduction delay plus a margin of error.

9. The implantable cardiac pacemaker of claim 1, wherein the response initiates the extended post ventricular atrial refractory period and the programmed ventricular blanking period simultaneously.

8. The implantable cardiac pacemaker of 7, wherein the margin of error is equal to approximately 10-30% of the interventricular conduction delay.

10. An implantable medical device, comprising;

biventricular pacing and sensing leads; and

a programmable cardiac pacing system coupled to the biventricular pacing and sensing leads, and having a preprogrammed premature ventricular contraction response function that initiates an extended post ventricular atrial refractory period for a first predetermined period of time of between about 350-450 ms, during which sensed atrial events are ignored, and initiates a programmed ventricular blanking period for a second predetermined period of time, following the detection of a premature ventricular contraction.

11. The cardiac pacemaker of claim 10, wherein the post ventricular atrial refractory period is approximately equal to 400 ms.

12. The implantable medical device of claim 10, wherein the pacing system will not restart the extended post ventricular atrial refractory period in response to ventricular events occurring during the programmed ventricular blanking period.

13. The implantable medical device of claim 10, wherein the extended post ventricular atrial refractory period and the programmed ventricular blanking period are initiated simultaneously.

14. The implantable medical device of claim 10, wherein the first predetermined period of time is longer than the second predetermined period of time.

15. The implantable medical device of claim 10, wherein the second predetermined period of time is approximately equal to an interventricular conduction delay.

16. The implantable medical device of claim 15, wherein the interventricular conduction delay is between about 80-180 ms.

17. The implantable medical device of claim 10, wherein the second predetermined period of time is approximately equal to an interventricular conduction delay plus a predetermined margin of error.

18. The implantable medical device of claim 17, wherein the margin of error is approximately 10-30% of the interventricular conduction delay.

19. The implantable medical device of claim 10, wherein the programmed ventricular blanking period prevents the double sensing of a single premature ventricular contraction.

20. The implantable medical device of claim 10, wherein a second extended post ventricular atrial refractory period will be initiated upon the determination that a subsequent premature ventricular contraction has occurred after the programmed ventricular blanking period terminates.

21. The implantable medical device of claim 10, wherein the second predetermined period of time is determined and programmed based on a measured interventricular conduction delay.

22. The implantable medical device of claim 21, wherein the interventricular conduction delay is measured prior to implanting the implantable medical device.

23. The implantable medical device of claim 21, wherein the interventricular conduction delay is measured after implanting the implantable medical device.

24. The implantable medical device of claim 21, wherein the second predetermined period of time is programmed to be approximately equal to the measured interventricular conduction delay.

25. The implantable medical device of claim 21, wherein the second predetermined period of time is programmed to be approximately equal to the measured interventricular conduction delay plus a predetermined margin of error.

26. The implantable medical device of claim 21, wherein the second predetermined period of time is programmed to be approximately equal to the measured interventricular conduction delay plus a predetermined margin of error.

27. The implantable medical device of claim 26, wherein the margin of error is equal to about 10-30% of the measured interventricular conduction delay.

28. The implantable medical device of claim 10, wherein the second predetermined period of time is set by a measurement made by the cardiac pacing system through the biventricular pacing and sensing leads, of an interventricular conduction delay.

29. A method of preventing pacemaker mediated tachycardia in a biventricular cardiac pacing system, the method comprising:

detecting a premature ventricular contraction;

initiating an extended post ventricular atrial refractory period of between about 350-450 ms during which atrial events are not sensed by the cardiac pacing system; and

initiating a programmable ventricular blanking period, during which ventricular events are not sensed by the cardiac pacing system.

30. The method of claim 29, wherein the extended post ventricular atrial refractory period and the programmed ventricular blanking period are initiated simultaneously.

31. The method of claim 29, further comprising:

terminating the programmed ventricular blanking period after the expiration of a first time period; and

terminating the extended post ventricular atrial refractory period after the expiration of a second time period, wherein the second time period is longer than the first time period.

32. The method of claim 31, further comprising:

setting the first time period to be approximately equal to an interventricular conduction delay.

33. The method of claim 31, further comprising:

setting the first time period to be approximately equal to an interventricular conduction delay plus a margin of error.

34. The method of claim 33, wherein the margin of error is approximately 10-30% of the interventricular conduction delay.

35. The method of claim 31, further comprising:

measuring an interventricular conduction delay; and

programming the cardiac pacing system to set the first time period based on the measured interventricular conduction delay.

36. The method of claim 35, wherein the first time period is set to be approximately equal to the interventricular conduction delay.

37. The method of claim 35, wherein the first time period is set to be approximately equal to the interventricular conduction delay plus a margin of error.

38. The method of claim 37, wherein margin of error is approximately 10-30% of the interventricular conduction delay.

39. A method of utilizing a biventricular cardiac pacing system, the method comprising:

providing a first ventricular lead and a second ventricular lead;

sensing atrial and ventricular events;

classifying a sensed ventricular event following another ventricular event without an intervening atrial event as a premature ventricular contraction;

initiating a first time period, during which atrial events are blanked out by the cardiac pacing system so that pacemaker mediated tachycardia is avoided; and

initiating a second time period, during which ventricular events are blanked out by the cardiac pacing system, wherein the second time period is at least as long as an interventricular conduction delay so that an event sensed by the first ventricular lead and classified as the premature ventricular contraction is not subsequently classified as another premature ventricular contraction when sensed by the second ventricular lead, so that an extended ventricular sensing cycle is avoided.

40. The method of claim 39, further comprising:

measuring the interventricular conduction delay; and

setting the second time period based on the measured interventricular conduction delay.

41. The method of claim 40, further comprising:

adding a margin of error to the second time period.

42. The method of claim 41, wherein the margin of error is equal to (10-30%) of the measured interventricular conduction delay.

43. An implantable programmable biventricular cardiac pacing system, comprising:

an atrial lead;

a first ventricular lead;

a second ventricular lead;

a microprocessor coupled to the atrial lead and the first and second ventricular leads, the microprocessor being configured to monitor sensed ventricular and atrial events so that a ventricular event sensed after another ventricular event without an intervening atrial sense is determined to be a premature ventricular contraction; and

a programmable microcomputer circuit coupled to the microprocessor and including an algorithm for responding to a determined premature ventricular contraction by initiating an extended post ventricular atrial refractory period, during which atrial events are blanked for a period of between about 350-450 ms, and initiating a programmable ventricular blanking period having a duration equal to a measured value of an interventricular conduction delay plus a margin of error equal to about 10-30% of the interventricular conduction delay, during which ventricular events sensed by the first or the second ventricular lead are ignored so that both pacemaker mediated tachycardia and extended ventricular sensing are avoided by the cardiac pacing system.

44. An implantable cardiac pacemaker, comprising:

means for sensing biventricular events; and

means for controlling the implantable cardiac pacemaker based in part on signals received from the means for sensing biventricular events, and initiating an extended post ventricular atrial refractory period of between about 350-450 ms, during which sensed atrial events are ignored, and a programmable ventricular blanking period in response to a premature ventricular contraction.

45. The implantable cardiac pacemaker of claim 44, wherein the post ventricular atrial refractory period is approximately equal to 400 ms.

46. The implantable cardiac pacemaker of claim 44, wherein the ventricular blanking period has a length of time that corresponds to a length of time defined by an interventricular conduction delay.

47. The implantable cardiac pacemaker of claim 44, wherein the ventricular blanking period has a length of time that is approximately equal to a length of time defined by an interventricular conduction delay.

48. The implantable cardiac pacemaker of claim 47, wherein the interventricular conduction delay is between about 80-180 ms.

49. The implantable cardiac pacemaker of claim 44, wherein the ventricular blanking period has a length of time that is approximately equal to a length of time defined by an interventricular conduction delay plus a margin of error.

51. The implantable cardiac pacemaker of claim 44, wherein the response initiates the extended post ventricular atrial refractory period and the programmed ventricular blanking period simultaneously.

50. The implantable cardiac pacemaker of 49, wherein the margin of error is equal to approximately 10-30% of the interventricular conduction delay.

52. A biventricular cardiac pacing system configured to prevent pacemaker mediated tachycardia, comprising:

means for detecting a premature ventricular contraction;

means for initiating an extended post ventricular atrial refractory period of between about 350-450 ms during which atrial events are not sensed by the cardiac pacing system; and

means for initiating a programmable ventricular blanking period, during which ventricular events are not sensed by the cardiac pacing system.

53. The cardiac pacing system of claim 52, wherein the extended post ventricular atrial refractory period and the programmed ventricular blanking period are initiated simultaneously.

54. The cardiac pacing system of claim 52, further comprising:

means for terminating the programmed ventricular blanking period after the expiration of a first time period; and

means for terminating the extended post ventricular atrial refractory period after the expiration of a second time period, wherein the second time period is longer than the first time period.

55. The cardiac pacing system of claim 54, wherein the first time period is approximately equal to an interventricular conduction delay.

56. The cardiac pacing system of claim 54, further comprising:

means for setting the first time period to be approximately equal to an interventricular conduction delay plus a margin of error.

57. The cardiac pacing system of claim 56, wherein the margin of error is approximately 10-30% of the interventricular conduction delay.

58. The cardiac pacing system of claim 54, further comprising:

means for measuring an interventricular conduction delay; and

means for programming the cardiac pacing system to set the first time period based on the measured interventricular conduction delay.

59. The cardiac pacing system of claim 58, wherein the first time period is approximately equal to the interventricular conduction delay.

60. The cardiac pacing system of claim 58, wherein the first time period is approximately equal to the interventricular conduction delay plus a margin of error.

61. The cardiac pacing system of claim 60, wherein the margin of error is approximately 10-30% of the interventricular conduction delay.

62. A biventricular cardiac pacing system, comprising:

means for sensing atrial and biventricular events;

means for classifying a sensed ventricular event following another ventricular event without an intervening atrial event as a premature ventricular contraction;

means for initiating a first time period, during which atrial events are blanked out by the cardiac pacing system so that pacemaker mediated tachycardia is avoided; and

means for initiating a second time period, during which ventricular events are blanked out by the cardiac pacing system, wherein the second time period is at least as long as an interventricular conduction delay so that an event sensed by the first ventricular lead and classified as the premature ventricular contraction is not subsequently classified as another premature ventricular contraction when sensed by the second ventricular lead, so that an extended ventricular sensing cycle is avoided.

63. The cardiac pacing system of claim 62, further comprising:

means for measuring the interventricular conduction delay; and

means for setting the second time period based on the measured interventricular conduction delay.

64. The cardiac pacing system of claim 63, wherein a margin of error is added to the second time period.

65. The cardiac pacing system of claim 64, where in the margin of error is equal to (10-30%) of the measured interventricular conduction delay.