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Peptide nucleic acids having 2,6-diaminopurine nucleobases

  • US 6,613,873 B1
  • Filed: 06/21/1999
  • Issued: 09/02/2003
  • Est. Priority Date: 05/24/1991
  • Status: Expired due to Fees
First Claim
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1. A peptide nucleic acid having formula:

  • embedded imagewherein;

    each L is independently selected from a group consisting of naturally-occurring nucleobases and non-naturally-occurring nucleobases, at least one of said L being a 2,6-diaminopurine nucleobase;

    each R7′

    is independently hydrogen or C1-C8 alkylamine;

    Rh is OH, NH2 or NHLysNH2;

    Ri is H, COCH3 or t-butoxycarbonyl; and

    n is an integer from 1 to 30.

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