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Composition and method for treatment of otitis media

  • US 6,616,913 B1
  • Filed: 08/16/2000
  • Issued: 09/09/2003
  • Est. Priority Date: 11/28/1999
  • Status: Expired due to Term
First Claim
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1. A method of treating otitis media comprising administering a dose of a mixture of lipid crystals, as an aerosol, through an external nasal airway of a mammal, said mixture being comprised of:

  • one or more lipid surfactant, one or more spreading agent and at least one propellant in which said surfactants and spreading agents are not soluble, said surfactants and spreading agents being selected from the group consisting of cholesteryl esters, phospholipids, carbohydrates, and proteins, all in powder form and said surfactants being present in an amount of from about 80 to about 95.5 weight percent and said spreading agents being present in an amount of from about 20 to about 0.5 weight percent based upon total weight of said lipid surfactants and spreading agents in said mixture, wherein when said propellants are evaporated therefrom, said aerosolized mixture of lipid crystals is provided.

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