×

Method of closing a cell containment device with a wet seal

  • US 6,617,151 B1
  • Filed: 02/29/2000
  • Issued: 09/09/2003
  • Est. Priority Date: 02/29/2000
  • Status: Expired due to Term
First Claim
Patent Images

1. A method of closing a cell containment device comprising:

  • providing a cell containment device comprising a permeable membrane made of a fluoropolymer, said permeable membrane delimiting a space for containing cells therein, a closure region comprising a thermoplastic polymer in association with the permeable membrane and means for placing cells in said space through said closure region, wherein said closure region is closeable with a cell-tight seal formed in the presence of an aqueous liquid;

    wetting said permeable membrane and said thermoplastic polymer with an aqueous liquid; and

    applying sufficient heat to at least one portion of said wetted thermoplastic polymer to cause said wetted thermoplastic polymer to melt and flow along surfaces and into available interstices of the permeable membrane to create at least one cell-tight seal and provide a cell containment device suitable for use as a medical device.

View all claims
  • 2 Assignments
Timeline View
Assignment View
    ×
    ×