Method and apparatus for producing homogenous cavitation to enhance transdermal transport
First Claim
1. An ultrasound source comprising:
- an ultrasound transmitting element having an axis and a first cross-section along said axis, said ultrasound transmitting element having a first axial end and a second axial end, said first axial end operable to produce ultrasonic waves; and
said first axial end comprising a matrix of ultrasound producing portions, said portions defined by a first series of parallel axial cuts and a second series of parallel axial cuts, said second series of parallel axial cuts are approximately perpendicular to said first series of parallel axial cuts and said matrix having the first cross-section;
wherein the ultrasound producing portions, which are completely bounded by said cuts, each has a substantially rectangular cross-section parallel to said first cross-section.
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Abstract
The present invention is directed to apparatus and methods for producing homogenous cavitation. An ultrasound souce comprising an ultrasound transmitting element having an axis and a cross-section along the axis is disclosed The ultrasound transmitting element also has a first axial end and a second axial end operable to produce ultrasonic waves. The cross-section has an area having a maximum value at the first axial end and a minimum value at the second axial end. A method for producing homogenous cavitation at an area of skin comprises creating a volume of fluid having a uniformly dispersed concentration of cavitation nuclei adjacent the area of skin. Ultrasound is then applied to the volume of fluid and causes cavitation at the cavitation nuclei.
50 Citations
24 Claims
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1. An ultrasound source comprising:
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an ultrasound transmitting element having an axis and a first cross-section along said axis, said ultrasound transmitting element having a first axial end and a second axial end, said first axial end operable to produce ultrasonic waves; and
said first axial end comprising a matrix of ultrasound producing portions, said portions defined by a first series of parallel axial cuts and a second series of parallel axial cuts, said second series of parallel axial cuts are approximately perpendicular to said first series of parallel axial cuts and said matrix having the first cross-section;
wherein the ultrasound producing portions, which are completely bounded by said cuts, each has a substantially rectangular cross-section parallel to said first cross-section. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. An ultrasound source comprising:
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an ultrasound transmitting element having an axis and a cross-section along said axis, said ultrasound transmitting element having a first axial end and a second axial end, said second axial end operable to produce ultrasonic waves;
said cross-section having an area having a maximum value at the first axial end and a minimum value at the second axial end; and
said first axial end comprising a matrix of ultrasound producing portions, said portions defined by a first series of parallel axial cuts and a second series of parallel axial cuts, said second series of parallel axial cuts are approximately perpendicular to said first series of parallel axial cuts and said matrix having the first cross-section;
wherein the ultrasound producing portions, which are completely bounded by said cuts, each has a substantially rectangular cross-section parallel to said first cross-section. - View Dependent Claims (11, 12, 13, 14, 15, 16, 17)
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18. A method for producing homogenous cavitation at an area of skin comprising:
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creating a volume of fluid adjacent the area of skin, said fluid having a uniformly dispersed concentration of cavitation nuclei therein; and
applying ultrasound to the volume of fluid from an ultrasound transmitting element having an axis and a cross-section along said axis, said ultrasound transmitting element having a first axial end and a second axial end, said second axial end operable to produce ultrasonic waves, said first axial end comprising a matrix of ultrasound producing portions, said portions defined by a first series of parallel axial cuts and a second series of parallel axial cuts, said second series of parallel axial cuts are approximately perpendicular to said first series of parallel axial cuts and said matrix having the first cross-section, wherein the ultrasound producing portions, which are completely bounded by said cuts, each has a substantially rectangular cross-section parallel to said first cross-section;
wherein the ultrasound causes cavitation to begin at or around the cavitation nuclei. - View Dependent Claims (19, 20, 21, 22, 23, 24)
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Specification