Automatic injection device

• US 6,620,137 B2
• Filed: 08/07/2001
• Issued: 09/16/2003
• Est. Priority Date: 05/15/1998
• Status: Expired due to Term

• Current Assignee: TecPharma Licensing AG (Ypsomed Holding AG)
• Original Assignee: Disetronic Licensing Ag (Roche Holding AG)
• Inventors: Jost, Stephan, Hostettler, Peter, Kirchhofer, Fritz, Steck, Jürg
• Primary Examiner(s): Casler, Brian L.
• Assistant Examiner(s): Sirmons, Kevin C.
• Application Number:
  US09/924,048
• Publication Number:
  US 20010049496A1
• Time in Patent Office: 770 Days
• Field of Search: 604/110, 604/131-136, 604/158, 604/171, 604/181, 604/184, 604/187, 604/188, 604/192, 604/193, 604/208-211, 604/218, 604/264, 604/272, 604/220, 604/506
• US Class Current: 604/218
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/2086 having piston damping means, e.g. axially or rotationally acting retarders
• CPC Class Codes: A61M 2005/3247 Means to impede repositioning of protection sleeve from needle covering to needle uncovering position
• CPC Class Codes: A61M 2205/14 Detection of the presence or absence of a tube, a connector or a container in an apparatus
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/2066 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/2448 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/3155 by rotational movement of dose setting member, e.g. during setting or filling of a syringe
• CPC Class Codes: A61M 5/31595 Pre-defined multi-dose administration by repeated overcoming of means blocking the free advancing movement of piston rod, e.g. by tearing or de-blocking
• CPC Class Codes: A61M 5/3202 Devices for protection of the needle before use, e.g. caps A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001
• CPC Class Codes: A61M 5/326 Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
• CPC Class Codes: A61M 5/46 having means for controlling depth of insertion

Abstract

The present invention provides an auto-injection device including a housing, a container from which a product is dispensed by advancing a piston, the container shiftably accommodated by the housing and carrying a needle, and a drive unit including a driven member, wherein the driven member is shiftably accommodated by the housing and, during an auto-injection, is adapted for inserting the needle and advancing the container to a predetermined frontal position in relation to the housing and advancing the piston within the container for dispensing of the product, wherein the driven member remains uncoupled with the piston until the container reaches its frontal position, and upon the container reaching its frontal position, the driven member detaches from the container and couples with the piston for advancing the piston within the container.

Claims

1. An injection device for administering a product, comprising:

a) a housing;

b) a piston disposed within the housing; and

c) a driven member shiftably disposed within the housing, wherein the driven member remains uncoupled with the piston until the driven member reaches a predetermined frontal position, and upon the driven member reaching the predetermined frontal position, the driven member becomes coupled with the piston wherein the injection device has a longitudinal axis and the coupling between the driven member and the piston is caused by a movement of the driven member around a rotational axis.

2. The device of claim 1 wherein the coupling between the driven member and the piston is caused by a disengagement of the driven member from a positive locking connection.

3. The device of claim 1 wherein the coupling between the driven member and the piston is caused by a disengagement of the driven member from a non-positive locking connection.

4. The device of claim 1 further comprising a container shiftably disposed within the housing wherein the driven member is operably engaged with the container before being operably engaged with the piston.

5. The device of claim 4 wherein the container further comprises a needle.

6. The device of claim 4 further comprising a sefety sleeve shiftably arranged on the housing and locked in a frontal position surrounding the needle against rearward shifting relative to the housing when the needle is in an advanced position.

7.An injection device for administering a product, comprising:

(a) a housing;

(b) a piston shiftably disposed within the housing;

(c) a container shiftably disposed within the housing, the piston operably associated with the container; and

(d) a driven element shiftably disposed within the housing, the driven element is adapted to being adapted to engagingly advance the container to a predetermined position, wherein once the container reaches the predetermined position, the driven element disengage from the container and operably engages and advances the piston.

7. The device of claim 7 wherein the operable engagement between the driven member and the piston is enabled by a rotational movement of the driven member.

8. The device of claim 7 wherein the operable engagement between the driven member and the piston is enabled by a disengagement of the driven member from a positive locking connection.

9. The device of claim 7 wherein the operable engagement between the driven member and the piston is enabled by a disengagement of the driven member from a non-positive locking connection.

10. The device of claim 7 wherein the container further comprises a needle.

11. The device of claim 11 further comprising a safety sleeve shiftably arranged on the housing and locked in a frontal position surrounding the needle against rearward shifting relative to the housing when the needle is in an advanced position.

12. An injection device for administering a product, comprising:

a) a housing;

b) an outlet associated with the housing;

c) a container shiftably disposed within the housing, the container being capable of retractable advance through the outlet; and

d) a driven member shiftably disposed within the housing, wherein the driven member is operably engaged with the container until the container is shifted to a predetermined frontal position, whereafter the driven member becomes operably engaged with a piston.

13. The device of claim 13 wherein the injection device has a longitudinal axis and the operable engagement between the driven member and the piston is caused by a rotational movement of the driven member around a rotational axis generally parallel to the longitudinal axis.

14. The device of claim 13 wherein the operable engagement between the driven member and the piston is caused by a disengagement of the driven member from a positive locking connection with the container.

15. The device of claim 13 wherein the operable engagement between the driven member and the piston is caused by a disengagement of the driven member from a non-positive locking connection with the container.

16. The device of claim 13 wherein the container further comprises a needle.

17. The device of claim 17 wherein the container further comprises a chamber in communication with the needle.

18. The device of claim 17 further comprising a safety sleeve shiftably arranged on the housing and locked in a frontal position surrounding the needle against rearward shifting relative to the housing when the needle is in an advanced position.

19. A method for administering a product through an injection device having a driven element and a piston, comprising the steps of:

(a) propelling the driven element to advance a container into a predetermined position;

(b) disengaging the driven element from the container;

(c) engaging the driven element to the piston; and

(d) driving the piston with the driven element for ejecting the product.

20. The method of claim 20 further comprising the step of engaging the driven element to the container with a positive locking connection.

21. The method of claim 20 further comprising the step of engaging the driven member to the container with a non-positive locking connection.

22. The method of claim 20 wherein the step of engaging the driven element to the piston further comprises a rotational movement of the driven member around a rotational axis.

23. The method of claim 20 wherein the step of propelling the driven element to advance the container into a predetermined position further comprises the substep of piercing a target tissue.