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Method and apparatus for safety delivering medicants to a region of tissue using imaging, therapy and temperature monitoring ultrasonic system

  • US 6,623,430 B1
  • Filed: 02/10/2000
  • Issued: 09/23/2003
  • Est. Priority Date: 10/14/1997
  • Status: Expired due to Term
First Claim
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1. A method for the controlled delivery of a medicant to a region of interest within a patient'"'"'s body comprising the steps of:

  • administering a thermosensitive liposome encased medicant to the region of interest;

    locating the region of interest containing the thermosensitive liposome using ultrasound imaging with a single ultrasound transducer;

    applying ultrasound therapy with the single ultrasound transducer to heat the region of interest containing the thermosensitive liposome;

    monitoring the temperature of the region of interest containing the thermosensitive liposome using ultrasound imaging with the single ultrasound transducer to create a temperature profile; and

    alternating application of ultrasound therapy and ultrasound imaging with the single ultrasound transducer until a predetermined temperature threshold is reached.

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