System for blocking the passage of emboli through a body vessel

• US 6,623,450 B1
• Filed: 12/17/1999
• Issued: 09/23/2003
• Est. Priority Date: 12/17/1999
• Status: Expired due to Term

• Current Assignee: Advanced Cardiovascular Systems Incorporated
• Original Assignee: Advanced Cardiovascular Systems Incorporated
• Inventors: Dutta, Debashis
• Primary Examiner(s): Kennedy, Sharon
• Assistant Examiner(s): Thompson, Michael M
• Application Number:
  US09/466,366
• Time in Patent Office: 1,376 Days
• Field of Search: 604/96.01, 604/104-108, 604/48, 606/159, 606/191, 606/194-200
• US Class Current: 604/96.01
• CPC Class Codes: A61F 2/01 Filters implantable into blood vessels
• CPC Class Codes: A61F 2230/0006 circular

Abstract

An expandable filtering material expands within a body vessel (e.g. artery) when fluid flows through the vessel. Expandable pockets in the filtering material trap emboli released in the fluid. The filtering material is inserted into the vessel at a particular position distal to a lesion in the direction of the fluid flow. A protective sleeve covers the filtering material. An interventional device is disposed in the vessel at the lesion position to treat the lesion. The sleeve is removed from the expandable filtering material thereby expanding the filtering material within the vessel. The interventional device treats the lesion and opens up the vessel at the lesion position. The interventional device is thereafter removed. Retaining pockets in the expandable filtering material trap emboli released in the fluid of the body vessel.

Claims

1. A device for passing a fluid through a vessel while blocking the passage of emboli through the vessel, comprising:

a porous hydrogel filtering material having properties of being expanded within the vessel when subjected to an external stimulus and having properties of passing fluid therethrough while blocking the passage of emboli contained in the fluid, the filtering material being normally in a contracted condition for positioning within the vessel.

2. The device of claim 1, wherein:

the porous hydrogel filtering material is expandable within the vessel when subjected to a stimulus selected from a group consisting of temperature, pH, electrical field, magnetic field, ionic field, pressure, stress, light intensity, solvent, and chemicals.

3. The device of claim 2, wherein:

the filtering material has properties of being contracted when the stimulus is removed from the filtering material.

4. A system for treating a lesion in a body vessel and allowing fluid to pass through the vessel while blocking the passage of emboli released in the fluid, comprising:

a porous hydrogel filtering material disposable in the vessel at a position past the lesion which is contractable and expandable, the filtering material being contracted during positioning in the vessel and being expandable when subjected to an external stimulus, the filtering material having properties when expanded for passing fluid therethrough while blocking the passage of the emboli; and

an interventional device for treating the lesion in the vessel.

5. The system of claim 4, wherein:

the porous hydrogel filtering material is expandable when the filtering material is subjected to a stimulus selected from a group consisting of temperature, pH, electrical field, magnetic field, ionic field, pressure, stress, light intensity, solvent, and chemicals.

6. The system of claim 5, wherein:

the hydrogel has properties of contracting when the stimulus is removed.

7. A system for passing a fluid through a vessel while blocking the passage of emboli in the vessel, comprising:

a filtering member made from porous hydrogel having properties of expanding when subjected to an external stimulus and having properties of passing fluid while blocking the passage of emboli when expanded, the filtering member being normally disposed in a contracted condition for positioning the filtering member in the vessel and having properties of being expanded after the disposition of the filtering member in the vessel.

8. The system of claim 7, including:

a sleeve removably disposed on the filtering member for retaining the filtering member in the contracted condition, there being a plurality of pockets in the filtering member with dimensions for trapping the emboli thereby preventing the emboli from passing through the filtering member.

9. The system of claim 8, wherein:

the sleeve is constructed to be disposed on the filtering member after the trapping of emboli by the filtering member to facilitate the removal of the filtering member from the vessel and to retain the emboli in the filtering member during such removal.

10. A system for treating a lesion in a body vessel and passing a fluid through a vessel while blocking the passage of emboli in the fluid, comprising:

a porous hydrogel filtering material disposable in the vessel at a position past the lesion in the direction of fluid flow, the filtering material being contractible and expandable, the filtering material being normally contracted and having properties of expanding within the vessel when exposed to an external stimulus in the vessel, the filtering material having properties when expanded for passing the fluid in the vessel while blocking the passage of the emboli in the vessel; and

an interventional device for treating the lesion.

11. The system of claim 10, wherein:

pockets are disposed in the expandable material to trap the emboli flowing in the vessel.

12. The system of claim 11, wherein:

a sleeve is disposed on the expandable filtering material in the contracted condition to provide for the movement of the expandable filtering material and the sleeve through the vessel to a position distal to the lesion in the direction of the fluid flow; and

the sleeve is removable from the expandable filtering material to provide for the expansion of the expandable filtering material and to provide for the trapping of the emboli in the pockets of the expandable member.

13. The system of claim 11, wherein:

the porous hydrogel filtering material is expandable when the filtering material is subjected to a stimulus selected from a group consisting of temperature, pH, electrical field, magnetic field, ionic field, pressure, stress, light, solvent and chemicals.

14. A device for passing a fluid through a vessel while blocking the passage of emboli through the vessel, comprising:

a filtering material having properties of being expanded within the vessel when subjected to an external stimulus and having properties of passing fluid therethrough while blocking the passage of emboli contained in the fluid, the filtering material being normally in a contracted condition for positioning within the vessel, wherein the filtering material is expandable within the vessel when subjected to a stimulus selected from a group consisting of pH, magnetic field, ionic field, light intensity, solvents and chemicals.

15. The device of claim 14, including:

a guide wire upon which the filtering material is disposed.

16. The device of claim 15, including:

a sleeve removably disposed on the filtering member for retaining the filtering member in the contracted condition, there being a plurality of pockets in the filtering member with dimensions for trapping the emboli thereby preventing the emboli from passing through the filtering member.

17. The system of claim 16, wherein:

the sleeve is constructed to be disposed on the filtering member after the trapping of emboli by the filtering member to facilitate the removal of the filtering member from the vessel and to retain the emboli in the filtering member during such removal.

18. A system for treating a lesion in a body vessel and allowing fluid to pass through the vessel while blocking the passage of emboli released in the fluid, comprising:

a filtering material disposable in the vessel at a position past the lesion which is contractable and expandable, the filtering material being contracted during positioning in the vessel and being expandable when subjected to an external stimulus selected from a group consisting of pH, magnetic field, ionic field, light intensity, solvents and chemicals, the filtering material having properties when expanded for passing fluid therethrough while blocking the passage of the emboli; and

an interventional device for treating the lesion in the vessel.

19. The device of claim 18, including:

a guide wire upon which the filtering material is disposed.

20. The device of claim 19, including:

a sleeve removably disposed on the filtering member for retaining the filtering member in the contracted condition, there being a plurality of pockets in the filtering member with dimensions for trapping the emboli thereby preventing the emboli from passing through the filtering member.

21. A system for passing a fluid through a vessel while blocking the passage of emboli in the vessel, comprising:

a filtering member made from a filtering material having properties of expanding when subjected to an external stimulus selected from a group consisting of pH, magnetic field, ionic field, light intensity, solvents and chemicals and having properties of passing fluid while blocking the passage of emboli when expanded, the filtering member being normally disposed in a contracted condition for positioning the filtering member in the vessel and having properties of being expanded after the disposition of the filtering member in the vessel.

22. The device of claim 21, including:

a guide wire upon which the filtering member is disposed.

23. A system for treating a lesion in a body vessel and passing a fluid through a vessel while blocking the passage of emboli in the fluid, comprising:

a filtering material disposable in the vessel at a position past the lesion in the direction of fluid flow, the filtering material being contractible and expandable, the filtering material being normally contracted and having properties of expanding within the vessel when exposed to an external stimulus in the vessel selected from a group consisting of pH, light, solvents and chemicals, the filtering material having properties when expanded for passing the fluid in the vessel while blocking the passage of the emboli in the vessel; and

an interventional device for treating the lesion.

24. The device of claim 23, including:

a guide wire upon which the filtering material is disposed.