Hemodialyzer having improved dialysate perfusion

• US 6,623,638 B2
• Filed: 06/01/2001
• Issued: 09/23/2003
• Est. Priority Date: 06/01/2001
• Status: Expired due to Term

• Current Assignee: Baxter International Inc.
• Original Assignee: Baxter International Inc.
• Inventors: Slepicka, James S., Watkins, Randolph H., Prisco, Michael R.
• Primary Examiner(s): Kim, John
• Application Number:
  US09/871,864
• Publication Number:
  US 20030080047A1
• Time in Patent Office: 844 Days
• Field of Search: 210/321.6, 210/321.72, 210/321.79, 210/321.8, 210/321.88, 210/321.89, 210/450, 210/456, 210/500.23
• US Class Current: 210/321.79
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1627 Dialyser of the inside perfusion type, i.e. blood flow inside hollow membrane fibres or tubes
• CPC Class Codes: A61M 2202/0498 Urea
• CPC Class Codes: A61M 2205/15 Detection of leaks
• CPC Class Codes: B01D 2313/10 Specific supply elements
• CPC Class Codes: B01D 2313/12 Specific discharge elements
• CPC Class Codes: B01D 2313/21 Specific headers, end caps
• CPC Class Codes: B01D 61/20 Accessories; Auxiliary operations
• CPC Class Codes: B01D 63/0233 forming the bundle

Abstract

A dialyzer is provided comprising a casing defining an interior and including a dialysate inlet and a dialysate outlet. A plurality of fibers are located in the interior of the casing and define a fiber bundle. A dialysate inlet fluid channel is provided in fluid communication with the dialysate inlet and includes a plurality of flutes that extend into a portion of the fiber bundles, the flutes define an opening for allowing dialysate to flow from the inlet fluid channel into the interior of the casing. Methods of providing dialysis are also provided.

Claims

1. A dialyzer having a fluid inlet and a fluid outlet comprising:

a casing defining an interior and including a dialysate inlet and a dialysate outlet wherein the casing is in fluid communication with the fluid inlet and the fluid outlet;

a plurality of fibers located in the interior of the casing and defining a fiber bundle; and

a dialysate inlet fluid channel in fluid communication with the dialysate inlet and including a plurality of flutes that extend into a portion of the fiber bundles, the flutes defining an opening for allowing dialysate to flow from the inlet fluid channel into the interior of the casing.

2. The dialyzer of claim 1 including a dialysate outlet fluid channel in fluid communication with the dialysate outlet and including a plurality of flutes that extend into a portion of the fiber bundle, the flutes defining openings for allowing dialysate to flow from the interior of the casing into the dialysate outlet fluid channel.

3. The dialyzer of claim 2 wherein the outlet fluid channel and inlet fluid channel have substantially the same structure.

4. The dialyzer of claim 1 wherein the casing is constructed from plastic.

5. The dialyzer of claim 1 including eight flutes.

6. The dialyzer of claim 1 wherein a top portion of the dialysate inlet fluid channel is defined by potting material.

7. The dialyzer of claim 1 wherein the flutes circumscribe an entire circumference of a first end of the dialyzer.

8. The dialyzer of claim 1 wherein the opening in the flutes is a slot.

9. The dialyzer of claim 8 wherein each flute defines a separate opening.

10. A dialyzer having a fluid inlet and a fluid outlet comprising:

a casing defining an interior and having a first end having a dialysate inlet and a second end having a dialysate outlet wherein the casing is in fluid communication with the fluid inlet and the fluid outlet;

a fiber bundle including a plurality of fibers located within the interior and extending from the first end to the second end;

a fluid inlet channel in fluid communication with the dialysate inlet, the fluid inlet channel being defined in part by a portion of the casing that defines an exterior surface of the first end and an inner wall that circumscribes a portion of the interior, the inner wall including portions that extend into the fiber bundle, at least one of the portions including an aperture for allowing fluid to flow from the fluid inlet channel into the interior; and

a fluid outlet channel in fluid communication with the dialysate outlet, the fluid outlet channel being defined in part by a portion of the casing that defines an exterior surface of the second end and an inner wall that circumscribes a portion of the interior, the inner wall including portions that extend into the fiber bundle, at least one of the portions including an aperture for allowing fluid to flow from the interior into the fluid outlet channel.

11. The dialyzer of claim 10 wherein the inner wall defines a pluality of semicircular structures.

12. The dialyzer of claim 10 wherein the outlet fluid channel and inlet fluid channel have substantially the same structure.

13. The dialyzer of claim 10 wherein a top portion of the fluid inlet channel is defined by potting material.

14. The dialyzer of claim 10 wherein the aperture is a slot.

15. The dialyzer of claim 10 wherein the fluid inlet channel and fluid outlet channel includes at least six separate portions that extend into the fiber bundle each including an aperture.

16. A dialyzer having a fluid inlet and a fluid outlet comprising:

a casing defining an interior and including a first end having a dialysate inlet and a second end having a dialysate outlet wherein the casing is in fluid communication with the fluid inlet and the fluid outlet;

a fiber bundle located in the interior of the casing; and

a dialysate inlet in fluid communication with an inlet fluid channel, the inlet fluid channel defined, at least in part, by an interior wall of the casing, a potting material and an inner wall circumscribing the interior of the first end and including a plurality of members defining areas for receiving fibers of the fiber bundle and a portion that extends into the fiber bundles, each of the portions extending into the fiber bundles including an aperture for allowing dialysate to flow into the interior of the casing.

17. The dialyzer of claim 16 wherein the portions define flutes.

18. The dialyzer of claim 16 wherein the second end includes a dialysate outlet fluid channel including a plurality of flutes that extend into a portion of the fiber bundle, the flutes including openings for allowing dialysate to flow from the interior of the casing into the dialysate outlet fluid channel.

19. The dialyzer of claim 18 wherein the outlet fluid channel and inlet fluid channel have substantially the same structure.

20. The dialyzer of claim 17 including eight flutes.

21. The dialyzer of claim 17 wherein the opening in the flutes is a slot.