Analysis device for analyzing samples

• US 6,623,697 B2
• Filed: 01/19/2001
• Issued: 09/23/2003
• Est. Priority Date: 01/21/2000
• Status: Expired due to Fees

• Current Assignee: Roche Diagnostics Operations Incorporated (Roche Holding AG)
• Original Assignee: Roche Diagnostics GmbH (Roche Holding AG)
• Inventors: Fuerst, Otto, Jansen, Paul, Jaeck, Thomas
• Primary Examiner(s): Warden, Jill
• Assistant Examiner(s): Gordon, Brian R.
• Application Number:
  US09/766,509
• Publication Number:
  US 20010026772A1
• Time in Patent Office: 977 Days
• Field of Search: 422/100, 422/64, 422/73, 422/63, 436/180, 436/49, 137/263, 137/266
• US Class Current: 422/64
• CPC Class Codes: G01N 2035/00277 Special precautions to avoid contamination (e.g. enclosures, glove- boxes, sealed sample carriers, disposal of contaminated material)
• CPC Class Codes: G01N 35/02 using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations G01N35/0098 and G01N35/0099 take precedence
• CPC Class Codes: Y10T 137/4807 Tank type manifold [i.e., one tank supplies or receives from at least two others]
• CPC Class Codes: Y10T 137/4857 With manifold or grouped outlets
• CPC Class Codes: Y10T 436/114998 with treatment or replacement of aspirator element [e.g., cleaning, etc.]
• CPC Class Codes: Y10T 436/2575 Volumetric liquid transfer

Abstract

Analysis device for analyzing samples, in particular of body liquids, with respect to components contained therein. It comprises a plurality of liquid handling (LH) stations. At at least a part of the LH stations there is a production of liquid waste whereby said LH-station form liquid waste sources. The liquid waste is evacuated, with at least one pump, from the liquid waste sources, with different proportions of air, via a liquid waste conducting system, into a liquid waste container.

A substantial reduction of foam production is obtained by connecting at least two liquid waste sources to the liquid waste container via at least two liquid waste lines leading separately into the liquid waste container, whereas liquid waste sources with a higher average air proportion are connected to a first liquid waste line and liquid waste sources with a lower average air proportion are connected to a second liquid waste line.

Claims

1. In an analysis device for analyzing samples comprising a plurality of liquid handling (LH) stations which include processing stations, including at least one of a detection station, a dispensing station, washing station, and mixing station and wherein processing steps are performed to sample liquids contained in containers with processing tools including at least one of a dosing needle and a stirrer, and wherein liquid waste is produced at least at a part of the liquid handling stations, the improvement comprising:

a liquid waste conduction system comprising;

a plurality of liquid waste sources associated with said processing stations each of said liquid waste sources including different proportion of air;

a liquid waste container;

at least first and second primary waste lines leading to the liquid waste container;

a plurality of separate secondary waste lines leading from each of said plurality of liquid waste sources;

a line junction connecting at least one of said secondary waste lines with the first primary waste line and at least a second of said secondary waste lines with the second primary waste line;

at least one evacuation pump for transferring liquid waste from said liquid waste sources to said liquid waste container; and

wherein the first primary waste lines transports liquid waste with a higher proportion of air and the second primary waste line transports liquid waste with a lower air proportion.

2. The analysis device according to claim 1, wherein the at least one evacuation pump for transferring liquid waste from said liquid waste sources to said liquid waste container is a common multichannel pump.

3. The analysis device according to claim 2, wherein the multichannel pump is continuously driven.

4. The analysis device according to claim 2, wherein the pump is located in the secondary lines upstream form the line junction.

5. The analysis device according to claim 1, wherein the at least one of the liquid waste sources is a washing station for cleaning a processing tool by means of a washing liquid.

6. The analysis device according to claim 5, wherein the plurality of liquid waste sources include at least two washing stations and said washing stations are connected to at least one of said first and second primary waste lines via said secondary lines and said line junction.

7. The analysis device according to claim 5, wherein at least one washing station comprises a washing liquid container with a first evacuation point at the bottom of the washing liquid container and a second evacuation point at an overflow of the washing container.

8. The analysis device according to claim 7, wherein the first evacuation point and the second evacuation point are connected to a switch valve.

9. The analysis device according to claim 1, wherein the exit openings of the separate lines leading into the liquid waste container are arranged at most 1 cm from each other.