Stable liquid enzyme compositions with enhanced activity

• US 6,624,132 B1
• Filed: 06/29/2000
• Issued: 09/23/2003
• Est. Priority Date: 06/29/2000
• Status: Expired due to Term

• Current Assignee: Ecolab USA Incorporated (Ecolab, Inc.)
• Original Assignee: Ecolab, Inc.
• Inventors: Killeen, Yvonne Marie, Man, Victor Fuk-Pong, Lentsch, Steven Eugene
• Primary Examiner(s): Gupta, Yogendra N.
• Assistant Examiner(s): Elhilo, Eisa
• Application Number:
  US09/606,478
• Time in Patent Office: 1,181 Days
• Field of Search: 510/392, 510/530, 510/535, 510/531, 510/321, 510/532
• US Class Current: 510/392
• CPC Class Codes: C11D 3/046 Salts
• CPC Class Codes: C11D 3/38663 Stabilised liquid enzyme compositions

Abstract

The present invention relates to a liquid enzyme cleaning composition in which the enzyme is stable at alkaline pH and in the presence of water at concentrations of at least about 50 to about 60 weight percent. In one embodiment, the composition of the invention stabilizes the enzyme with potassium borate.

Claims

1. A liquid enzyme cleaning composition comprising surfactant, detersive enzyme, 10% to about 20% by weight boric acid salt, and 60% to about 85% by weight water;

the boric acid salt remaining dissolved in the cleaning composition at room temperature;

wherein the liquid enzyme cleaning composition is formulated to provide detersive enzyme that retains about 100% of its initial activity at ambient temperature for at least 11 months after forming the composition.

2. The composition of claim 1, wherein the boric acid salt comprises an alkali metal boric acid salt, an alkanol amine boric acid salt, or a combination thereof.

3. The composition of claim 2, wherein the boric acid salt comprises monoethanolammonium borate, diethanolammonium borate, triethanolammonium borate, or a combination thereof.

4. The composition of claim 1, wherein the boric acid salt comprises potassium borate.

5. The composition of claim 4, wherein the potassium borate comprises a combination of potassium hydroxide and boric acid.

6. The composition of claim 4, wherein the composition comprises about 10 to about 15 weight percent potassium borate.

7. The composition of claim 1, wherein the composition is a solution.

8. The composition of claim 1, wherein the composition comprises 60% by weight to about 70% by weight water.

9. The composition of claim 1, wherein the detersive enzyme retains at least 80% of its initial activity at 100°

F. for at least 70 days after forming the composition.

10. The composition of claim 1, wherein the detersive enzyme retains at least 40% of its initial activity at 120°

F. for at least 25 days after forming th composition.

11. The composition of claim 1, wherein the detersive enzyme comprises protease, amylase, lipase, cellulase, peroxidase, gluconase, or a combination thereof.

12. The composition of claim 11, wherein the detersive enzyme comprises alkaline protease, lipase, amylase, or a combination thereof.

13. The composition of claim 1, wherein the surfactant comprises amphoteric surfactant.

14. The composition of claim 13, wherein the amphoteric surfactant comprises a coconut derived surfactant comprising an ethylenediamine moiety, an amide moiety, an amino acid moiety, or a combination thereof;

and an aliphatic moiety.

15. The composition of claim 13, wherein the amphoteric surfactant comprises an alkyl amphodicarboxylic acid.

16. The composition of claim 13, wherein the amphoteric surfactant comprises C₁₂-alkyl-C(O)—

NH—

CH₂—

CH₂—

N⁺(CH₂—

CH₂—

CO₂Na)₂—

CH₂—

CH₂—

OH or C₁₂-alkyl-C(O)—

N(H)—

CH₂—

CH₂—

N⁺(CH₂—

CO₂Na)₂—

CH₂—

CH₂—

OH, or a combination thereof.

17. The composition of claim 13, wherein the amphoteric surfactant comprises disodium cocoampho dipropionate, disodium cocoampho diacetate, or a combination thereof.

18. The composition of claim 1, further comprising source of calcium ions, polyol builder, dye, or a combination thereof.

19. The composition of claim 18, wherein the surfactant comprises an amphoteric surfactant, the detersive enzyme comprises protease, the boric acid salt comprises potassium borate, the source of calcium ions comprises calcium chloride, the polyol comprises propylene glycol, and the builder comprises citric acid salt.

20. The composition of claim 19, comprising about 8% by weight surfactant, about 2% by weight protease, 10% to about 15% by weight potassium borate, about 0.25% by weight calcium chloride, about 8% by weight propylene glycol, and about 4% to about 7% by weight citric acid salt.

21. The composition of claim 1, further comprising a pH in the range of about 9 to about 10.

22. The composition of claim 1, wherein the liquid enzyme cleaning composition is formulated to provide detersive enzyme that has more than 100% of its initial activity after forming the composition.

23. A liquid enzyme cleaning composition comprising surfactant, detersive enzyme, 10% to about 20% by weight potassium borate, and 60% to about 85% by weight water;

the potassium borate remaining dissolved in the cleaning composition at room temperature.

24. The composition of claim 23, wherein the potassium borate comprises a combination of potassium hydroxide and boric acid.

25. The composition of claim 23, wherein the composition comprises about 10 to about 15 weight percent potassium borate.

26. The composition of claim 23, wherein the composition is a solution.

27. The composition of claim 23, wherein the composition comprises 60% by weight to about 70% by weight water.

28. The composition of claim 23, wherein the detersive enzyme retains about 100% of its initial activity at ambient temperature for at least 11 months after forming the composition.

29. The composition of claim 23, wherein the detersive enzyme retains at least 80% of its initial activity at 100°

F. for at least 70 days after forming the composition.

30. The composition of claim 23, wherein the detersive enzyme retains at least 40% of its initial activity at 120°

F. for at least 25 days after forming the composition.

31. The composition of claim 23, wherein the detersive enzyme comprises protease, amylase, lipase, cellulase, peroxidase, gluconase, or a combination thereof.

32. The composition of claim 31, wherein the detersive enzyme comprises alkaline protease, lipase, amylase, or a combination thereof.

33. The composition of claim 23, wherein the surfactant comprises amphoteric surfactant.

34. The composition of claim 33, wherein the amphoteric surfactant comprises a coconut derived surfactant comprising an ethylenediamine moiety, an amide moiety, an amino acid moiety, or a combination thereof, and an aliphatic moiety.

35. The composition of claim 33 wherein the amphoteric surfactant comprises an alkyl amphodicarboxylic acid.

36. The composition of claim 33, wherein the amphoteric surfactant comprises C₁₂-alkyl-C(O)—

NH—

CH₂—

CH₂—

N⁺(CH₂—

CH₂—

CO₂Na)₂—

CH₂—

CH₂—

OH or C₁₂-alkyl-C(O)—

N(H)—

CH₂—

CH₂—

N⁺(CH₂—

CO₂Na)₂—

CH₂—

CH₂—

OH, or a combination thereof.

37. The composition of claim 33, wherein the amphoteric surfactant comprises disodium cocoampho dipropionate, disodium cocoampho diacetate, or a combination thereof.

38. The composition of claim 23, further comprising source of calcium ions, polyol, builder, dye, or a combination thereof.

39. The composition of claim 38, wherein the surfactant comprises an amphoteric surfactant, the detersive enzyme comprises protease, the boric acid salt comprises potassium borate, the source of calcium ions comprises calcium chloride, the polyol comprises propylene glycol, and the builder comprises citric acid salt.

40. The composition of claim 38, comprising about 8% by weight surfactant, about 2% by weight protease, 10% to about 15% by weight potassium borate, about 0.25% by weight calcium chloride, about 8% by weight propylene glycol, and about 4% to about 7% by weight citric acid salt.

41. The composition of claim 23, further comprising a pH in the range of about 9 to about 10.

42. The composition of claim 23, wherein the liquid enzyme cleaning composition is formulated to provide detersive enzyme that has more than 100% of its initial activity after forming the composition.

43. A liquid enzyme cleaning composition comprising surfactant, a detersive enzyme, 10% to about 20% by weight alkanol amine boric acid salt, and 60% to about 85% by weight water.

44. The composition of claim 43, wherein the boric acid salt comprises monoethanolammonium borate, diethanolammonium borate, triethanolammonium borate, or a combination thereof.

45. A liquid enzyme cleaning composition comprising a surfactant;

a detersive enzyme;

60% to about 80% by weight water; and

10% to about 20% by weight potassium borate, monoethanolammonium borate, diethanolammonium borate, triethanolammonium borate, or a combination thereof;

the boric acid salt remaining dissolved in the cleaning composition at room temperature.

46. A liquid enzyme cleaning composition comprising surfactant, detersive enzyme, 10% to about 20% by weight boric acid salt, and greater than 80% by weight water;

the boric acid salt remaining dissolved in the cleaning composition at room temperature.