System and method of automatically adjusting sensing parameters based on temporal measurement of cardiac events

• US 6,625,490 B1
• Filed: 11/14/2001
• Issued: 09/23/2003
• Est. Priority Date: 11/14/2001
• Status: Expired due to Term

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Inventors: McClure, Kelly H., Bornzin, Gene A., Mai, Junyu
• Primary Examiner(s): Getzow, Scott M.
• Application Number:
  US09/992,739
• Time in Patent Office: 678 Days
• Field of Search: 607/4-28
• US Class Current: 607/9
• CPC Class Codes: A61N 1/3704 Circuits specially adapted therefor, e.g. for sensitivity control

Abstract

A system and method for automatically adjusting the sensing parameters in an implantable cardiac stimulation device is described. The adjustment is based on the amplitudes and the onsets and ends of cardiac events, such as R-waves, T-waves, far-field R-waves, and/or far-field T-waves. Having determined the onset and termination of the cardiac events for a given number of cardiac cycles, particular variables that characterize these cardiac events can be averaged and stored in memory. Such variables include the peak amplitudes sampled during a cardiac event, the duration of the cardiac event, and the duration between cardiac events. Based on the averaged variables, the system automatically adjusts the sensing parameters, such as sensitivity, and blanking and refractory periods.

Claims

1. A method of automatically adjusting a cardiac sensing parameter, comprising:

sensing the occurrence of a cardiac signal;

sampling the sensed cardiac signal to generate samples therefrom;

determining an onset and an end of the sensed cardiac signal from the samples;

determining the duration and amplitude of the cardiac signal; and

verifying the stability of the cardiac signal, wherein if stability is verified, calculating the cardiac sensing parameter based on the duration and amplitude of the cardiac signal.

2. The method according to claim 1, wherein calculating the sensing parameter comprises calculating a ventricular sensitivity.

3. The method according to claim 1, wherein calculating the sensing parameter comprises calculating an atrial sensitivity.

4. The method according to claim 1, wherein calculating the sensing parameter comprises calculating a post-ventricular atrial blanking period (PVAB).

5. The method according to claim 1, wherein calculating the sensing parameter comprises calculating a ventricular refractory period (VREF).

6. The method according to claim 1, wherein calculating the sensing parameter comprises calculating a post-ventricular atrial refractory period (PVARP).

7. The method according to claim 1, wherein sensing the occurrence of the cardiac signal comprises sensing the occurrence of any one or more of:

an atrial signal, a ventricular signal, or a combined atrial and ventricular signal.

8. The method according to claim 7, wherein sensing the occurrence of the cardiac signal comprises sensing the occurrence of any one or more of:

a P-wave, R-wave, or a T-wave.

9. The method according to claim 1, wherein determining the duration of the sensed cardiac signal comprises measuring the length of time between the onset and the end of the sensed cardiac signal.

10. The method according to claim 9, wherein determining the amplitude of the sensed cardiac signal comprises measuring a maximum absolute amplitude of the samples between the onset and the end of the cardiac signal.

11. The method according to claim 10, wherein sensing the occurrence of the cardiac signal comprises sensing the occurrence of any one or more of:

a P-wave, a R-wave, a T-wave, a far-field R-wave, a far-field T-wave, or an evoked response;

wherein determining the duration of the sensed cardiac signal comprises measuring the length of time between the onset and the end of any one or more of;

the P-wave, the R-wave, the T-wave, the far-field R-wave, the far-field T-wave, or the evoked response; and

wherein determining the amplitude of any one or more of;

the P-wave, the R-wave, the T-wave, the far-field R-wave, the far-field T-wave, or the evoked response, comprises measuring the maximum absolute amplitude of the sample between the onset and the end of any one or more of;

the P-wave, the R-wave, the T-wave, the far-field R-wave, the far-field T-wave, or the evoked response.

12. The method according to claim 10, wherein verifying the stability of the sensed signal comprises:

measuring a mean and a mean variance of the duration of any one or more of;

the P-wave, the R-wave, the T-wave, the far-field R-wave, the far-field T-wave, or the evoked response;

measuring a mean and a mean variance of the amplitude of any one or more of;

the P-wave, the R-wave, the T-wave, the far-field R-wave, the far-field T-wave, or the evoked response; and

determining if the mean variances of the duration and amplitude of any one or more of;

the P-wave, the R-wave, the T-wave, the far-field R-wave, the far-field T-wave, or the evoked response, are less than predetermined percentages of the means of the duration and amplitude, respectively.

13. The method according to claim 12, wherein stability is verified if the mean variance of the duration (RT duration) between the onset of the R-wave and the end of the T-wave is less than a predetermined percentage of the mean of the duration (RT duration).

14. The method according to claim 12, stability is verified if the mean variance of the maximum absolute amplitude of the T-wave is less than a predetermined percentage of the mean of the maximum absolute amplitude of the T-wave.

15. The method according to claim 12, wherein verifying the stability of the sensed signal comprises verifying the stability based on measurements made over three or more consecutive cardiac cycles.

16. The method according to claim 13, wherein calculating the sensing parameter comprises calculating a ventricular refractory period (VREF) according to the following equation:

17. The method according to claim 13, wherein calculating the sensing parameter comprises calculating a post-ventricular atrial refractory period (PVARP) according to the following equation:

18. The method according to claim 13, wherein calculating the sensing parameter comprises calculating a post-ventricular atrial blanking period (PVAB) according to the following equation:

19. The method according to claim 1, wherein calculating the cardiac sensing parameter comprises calculating a mean and a mean variance of the duration of the sensed cardiac signal.

20. The method according to claim 19, wherein verifying stability if the mean variance of the duration of the sensed cardiac signal is less than a predetermined percentage of the mean of the duration of the sensed cardiac signal.

21. A device for automatically adjusting a cardiac sensing parameter, comprising:

a sensor circuit that senses the occurrence of a cardiac signal;

a sampler, connected to the sensor circuit, to sample a sensed cardiac signal to generate samples therefrom;

a controller, connected to the sampler, to determine an onset and an end of the sensed cardiac signal from the samples, to determine the duration and amplitude of the sensed cardiac signal, and to verify the stability of the sensed signal; and

wherein if stability is verified, the controller is operative to calculate the cardiac sensing parameter based on the duration and amplitude of the sensed cardiac signal.

22. The device according to claim 21, wherein the sensing parameter comprises any one or more of:

a ventricular sensitivity;

an atrial sensitivity;

a post-ventricular atrial blanking period (PVAB);

a ventricular refractory period (VREF);

or

a post-ventricular atrial refractory period (PVARP).

23. The device according to claim 22, wherein the cardiac signal is any one or more of:

an atrial signal, a ventricular signal, or a combined atrial and ventricular signal.

24. The device according to claim 23, wherein the cardiac signal is any one or more of:

a P-wave, R-wave, a T-wave, a far-field R-wave, a far-field T-wave, or an evoked response.

25. The device according to claim 24, wherein the controller calculates a mean and a mean variance of the duration of the cardiac signal;

and

wherein the duration of the cardiac signal is the length of time between the onset and the end of the cardiac signal.

26. The device according to claim 25, wherein the amplitude of the cardiac signal is a maximum absolute amplitude of the samples between the onset and the end of the cardiac signal.

27. The device according to claim 26, wherein the controller verifies the stability of the signal if the mean variance of the duration of the cardiac signal is less than a predetermined percentage of the mean of the duration of the cardiac signal.

28. The device according to claim 27, wherein the controller determines the duration of the sensed cardiac signal by measuring the length of time between the onset and the end of any one or more of:

the P-wave, the R-wave, the T-wave, the far-field R-wave, the far-field T-wave, or the evoked response; and

wherein the controller further determines the amplitude of any one or more of;

the P-wave, the R-wave, the T-wave, the far-field R-wave, the far-field T-wave, or the evoked response, by measuring the maximum absolute amplitude of the sample between the onset and the end of any one or more of;

the P-wave, the R-wave, the T-wave, the far-field R-wave, the far-field T-wave, or the evoked response.

29. The device according to claim 28, wherein the controller verifies the stability of the sensed signal by:

measuring a mean and a mean variance of the duration of any one or more of;

the P-wave, the R-wave, the T-wave, the far-field R-wave, the far-field T-wave, or the evoked response;

measuring a mean and a mean variance of the amplitude of any one or more of;

the P-wave, the R-wave, the T-wave, the far-field R-wave, the far-field T-wave, or the evoked response; and

determining if the mean variances of the duration and amplitude of any one or more of;

the P-wave, the R-wave, the T-wave, the far-field R-wave, the far-field T-wave, or the evoked response, are less than predetermined percentages of the means of the duration and amplitude, respectively.

30. The device according to claim 29, wherein the controller verifies stability if any one or more of the following conditions is satisfied:

(1) the mean variance of the duration (RT duration) between the onset of the R-wave and the end of the T-wave is less than a predetermined percentage of the mean of the duration (RT duration);

or

(2) the mean variance of the maximum absolute amplitude of the T-wave is less than a predetermined percentage of the mean of the maximum absolute amplitude of the T-wave.

31. The device according to claim 30, wherein the controller calculates the sensing parameter by one or more of the following ways:

(1) calculating a ventricular refractory period (VREF) according to the following equation;

32. A device for automatically adjusting a cardiac sensing parameter, comprising:

means for sensing the occurrence of a cardiac signal;

means for sampling a sensed cardiac signal to generate samples therefrom;

means for determining an onset and an end of the sensed cardiac signal from the samples, for determining the duration and amplitude of the sensed cardiac signal, and for verifying the stability of the sensed signal; and

means for calculating the cardiac sensing parameter based on the duration and amplitude of the sensed cardiac signal if stability is verified.

33. The device according to claim 32, wherein the sensing parameter comprises any one or more of:

a ventricular sensitivity;

an atrial sensitivity;

a post-ventricular atrial blanking period (PVAB);

a ventricular refractory period (VREF);

or a post-ventricular atrial refractory period (PVARP);

wherein the cardiac signal is any one or more of;

an atrial signal, a ventricular signal, or a combined atrial and ventricular signal; and

wherein the cardiac signal is any one or more of;

a P-wave, R-wave, a T-wave, a far-field R-wave, a far-field T-wave, or an evoked response.