Anticoagulant internally coated needle

• US 6,626,874 B1
• Filed: 11/17/2000
• Issued: 09/30/2003
• Est. Priority Date: 03/19/1998
• Status: Active Grant

• Current Assignee: Smiths Medical ASD, Inc. (Smiths Group International Holdings Ltd.)
• Original Assignee: Portex, Inc. (Smiths Group International Holdings Ltd.)
• Inventors: Duchamp, Jacky G.
• Primary Examiner(s): Doerrler, William C
• Assistant Examiner(s): Zec, Filip
• Application Number:
  US09/714,288
• Time in Patent Office: 1,047 Days
• Field of Search: 604/265, 604/264, 604/266, 604/192, 604/198, 604/199, 604/164.08, 427/2.13, 427/2.28, 427/475, 427/476, 427/477, 427/478, 427/479, 427/480, 427/560, 427/565, 427/600
• US Class Current: 604/266
• CPC Class Codes: A61B 5/15003 for venous or arterial blood
• CPC Class Codes: A61B 5/150236 Pistons, i.e. cylindrical bodies that sit inside the syringe barrel, typically with an air tight seal, and slide in the barrel to create a vacuum or to expel blood
• CPC Class Codes: A61B 5/150244 Rods for actuating or driving the piston, i.e. the cylindrical body that sits inside the syringe barrel, typically with an air tight seal, and slides in the barrel to create a vacuum or to expel blood
• CPC Class Codes: A61B 5/150282 for piercing elements, e.g. blade, lancet, canula, needle
• CPC Class Codes: A61B 5/150389 Hollow piercing elements, e.g. canulas, needles, for piercing the skin
• CPC Class Codes: A61B 5/150519 Details of construction of hub, i.e. element used to attach the single-ended needle to a piercing device or sampling device
• CPC Class Codes: A61B 5/150671 comprising means to impede repositioning of protection sleeve from covering to uncovering position
• CPC Class Codes: A61B 5/150755 Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
• CPC Class Codes: A61B 5/153 Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
• CPC Class Codes: A61L 31/10 Macromolecular materials
• CPC Class Codes: A61M 2205/6081 Colour codes
• CPC Class Codes: A61M 5/283 by telescoping of ampoules or carpules with the syringe body
• CPC Class Codes: A61M 5/3216 Caps placed transversally onto the needle, e.g. pivotally attached to the needle base
• CPC Class Codes: A61M 5/3293 characterised by features of the needle hub
• CPC Class Codes: C08L 5/10 Heparin; Derivatives thereof

Abstract

To prevent blood from clotting or being diluted (which causes inaccuracy in the measurement of the characteristics of blood drawn from a patient), a needle assembly has the interior portion of its cannula and at least one portion of its hub covered by a dry coat of anticoagulant. To provide the dry coat of anticoagulant onto the interior surfaces of the cannula and the hub, a liquid anticoagulant is atomized thereto so that an even coat of the anticoagulant is provided to the interior surfaces of the cannula and hub. The volume and concentration of the anticoagulant atomized to the inside of the needle assembly are controlled as the liquid anticoagulant is ultra-sonically atomized to the interior portion of the needle assembly.

Claims

1. A method of manufacturing a non-clottable needle, comprising the steps of:

depositing a liquid anticoagulant to the interior surface of a needle; and

drying said liquid anticoagulant to fore a layer of crystallized anticoagulant at the interior surface of said needle.

2. Method of claim 1, wherein said depositing step comprises atomizing said liquid anticoagulant to the interior surface of said needle.

4. Method of claim 1, further comprising the steps of:

mating said needle to a syringe; and

flexibly coupling a sheath to said syringe, said sheath pivotable to fixedly envelop said needle.

6. Method of claim 1, wherein said anticoagulant comprises a heparin substance, and wherein said depositing step comprises the step of:

atomizing said heparin substance to the interior surface of said needle via ultra-sonic atomization.

7. Method of claim 1, further comprising the step of:

depositing said anticoagulant to the interior surface of said needle in a volume and/or concentration corresponding to the length of said needle.

8. Method of claim 1, wherein said depositing step comprises the step of:

atomizing the interior surface of said needle with lithium heparin powder mixed with de-ionized water.

9. Method of claim 1, wherein said depositing step comprises the step of:

atomizing the interior surface of said needle with any of ammonium heparin, zinc heparin, calcium heparin, low molecular weight heparin, sodium heparin, benzalkonium heparin, dermatome heparin, heparin fragments, and various forms of heparin peptidoglycan.

3. A method of manufacturing a non-clottable needle, comprising the steps of:

depositing a liquid anticoagulant to the interior surface of a needle;

drying said liquid anticoagulant to form a layer of crystallized anticoagulant at the interior surface of said needle;

extending said needle from a hub; and

depositing said anticoagulant to at least one portion of the interior surface of said hub.

5. A method of manufacturing a non-clottable needle, comprising the steps of:

depositing a liquid anticoagulant to the interior surface of a needle;

drying said liquid anticoagulant to form a layer of crystallized anticoagulant at the interior surface of said needle; and

drying said anticoagulant by air or by heat.