Micro infusion drug delivery device

• US 6,629,949 B1
• Filed: 09/29/2000
• Issued: 10/07/2003
• Est. Priority Date: 05/08/2000
• Status: Expired due to Fees

• Current Assignee: TecPharma Licensing AG (Ypsomed Holding AG)
• Original Assignee: Sterling Medivations, Inc. (Guided Therapeutics, Inc.)
• Inventors: Douglas, Joel S.
• Primary Examiner(s): Jiang, Chen Wen
• Application Number:
  US09/672,456
• Time in Patent Office: 1,103 Days
• Field of Search: 604/19, 604/20, 604/46, 604/47, 604/117, 600/556, 606/186, 606/183
• US Class Current: 604/46
• CPC Class Codes: A61M 2037/0023 Drug applicators using microneedles
• CPC Class Codes: A61M 2037/003 having a lumen
• CPC Class Codes: A61M 37/0015 by using microneedles
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons

Abstract

An infusion pump for use with standard pre-filled medication container and a drug delivery device for percutaneously administering a drug. The delivery device having a plurality of projections and a drug reservoir. The projections extend from the reservoir and are adapted for penetrating the stratum comeun for percutaneously administering a drug from the reservoir to produce a local or systemic physiological or pharmacological effect. The plurality of projections is formed by micro machining. The pump is made by using a micro-actuator and includes a housing having a lid which opens and closes so that the medication container can be inserted and supported in a delivery mode position.

Claims

1. A skin interface device, comprising:

a bottom portion;

a top portion which is attached to the bottom portion;

a plurality of projections located on the top portion, each of the plurality of projections has an opening extending therethrough, and wherein the projections extend in a direction non-perpendicular to the top portion;

a first passageway formed between the bottom portion and the top portion;

a second passageway formed on the bottom portion wherein the first passageway, the openings extending through the projections and the second passageway are interconnected so that fluid is able to flow through the second passageway into the first passageway and then into each respective opening extending through each of the plurality of projections and wherein at least a portion of the openings extending through the projections are non-perpendicular to the top portion.

2. The skin interface as claimed in claim 1, wherein the top portion and the bottom portion are attached by an adhesive.

3. The skin interface as claimed in claim 1, wherein the projections are made by plating gas discharge or sputtering operations and reapplying a photo resist to etch the geometries into layers.

4. The skin interface as claimed in claim 1, wherein a pump is connected to the skin interface through the second passageway.

5. The skin interface as claimed in claim 1, wherein the projections are curved.

6. A skin interface device, comprising:

a bottom portion;

a top portion which is attached to the bottom portion;

a plurality of projections located on the top portion, each of the plurality of projections has an opening extending therethrough;

a first passageway formed between the bottom portion and the top portion;

a second passageway formed on the bottom portion wherein the first passageway, the openings extending through the projections and the second passageway are interconnected so that fluid is able to flow through the second passageway into the first passageway and then into each respective opening extending through each of the plurality of projections and wherein at least a portion of the openings extending through the projections are non-perpendicular to the top portion, wherein the projections are bent at an angle.

7. A skin interface device, comprising:

a bottom portion;

a top portion which is attached to the bottom portion;

a plurality of projections located on the top portion, each of the plurality of projections has an opening extending therethrough;

a first passageway formed between the bottom portion and the top portion;

a second passageway formed on the bottom portion wherein the first passageway, the openings extending through the projections and the second passageway are interconnected so that fluid is able to flow through the second passageway into the first passageway and then into each respective opening extending through each of the plurality of projections and wherein at least a portion of the openings extending through the projections are non-perpendicular to the top portion, wherein at least a portion of the openings extending through the projections are disposed at an angle of less than 35 degrees to an axis perpendicular to the top portion.

8. A skin interface device, comprising:

a bottom portion;

a top portion which is attached to the bottom portion;

a plurality of projections located on the top portion, each of the plurality of projections has an opening extending therethrough;

a first passageway formed between the bottom portion and the top portion;

a second passageway formed on the bottom portion wherein the first passageway, the openings extending through the projections and the second passageway are interconnected so that fluid is able to flow through the second passageway into the first passageway and then into each respective opening extending through each of the plurality of projections and wherein at least a portion of the openings extending through the projections are non-perpendicular to the top portion, wherein at least a portion of the openings extending through the projections are disposed at an angle of about 10 degrees to an axis perpendicular to the top portion.