Herbal remedies for treating allergies and asthma

• US 6,630,176 B2
• Filed: 03/07/2001
• Issued: 10/07/2003
• Est. Priority Date: 03/07/2000
• Status: Expired due to Fees

• Current Assignee: Mount Sinai School of Medicine (Sinai Health System)
• Original Assignee: Icahn School of Medicine at Mount Sinai
• Inventors: Li, Xiu-Min, Sampson, Hugh A.
• Primary Examiner(s): TATE, CHRISTOPHER ROBIN
• Application Number:
  US09/800,815
• Publication Number:
  US 20030157126A1
• Time in Patent Office: 944 Days
• Field of Search: 424/725, 424/728, 424/739, 424/756, 424/195.16, 514/826
• US Class Current: 424/728
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 36/074 Ganoderma
• CPC Class Codes: A61K 36/232 Angelica
• CPC Class Codes: A61K 36/258 Panax (ginseng)
• CPC Class Codes: A61K 36/268 Asarum (wild ginger)
• CPC Class Codes: A61K 36/54 Lauraceae (Laurel family), e.g. cinnamon or sassafras
• CPC Class Codes: A61K 36/714 Aconitum (monkshood)
• CPC Class Codes: A61K 36/718 Coptis (goldthread)
• CPC Class Codes: A61K 36/736 Prunus, e.g. plum, cherry, peach, apricot or almond
• CPC Class Codes: A61K 36/756 Phellodendron, e.g. corktree
• CPC Class Codes: A61K 36/758 Zanthoxylum, e.g. pricklyash
• CPC Class Codes: A61K 36/9068 Zingiber, e.g. garden ginger

Abstract

The present invention provides herbal compositions that can prevent or reduce the severity, intensity, or duration of allergic and/or asthmatic symptoms and/or can prevent or delay the development of an allergic or asthmatic response to an antigen. The compositions may optionally include one or more adjuvants, cytokines, encapsulating materials, or pharmaceutical carriers or excipients, and may be administered prior to, during, or after the development of allergic or asthmatic symptoms in sensitized individuals. Alternatively or additionally, the compositions may be administered prior to sensitization to a particular antigen; preferably substantially concurrently with exposure to the antigen.

Claims

1. A composition for treating allergies or asthma comprising effective amounts of aqueous extracts of Fructus Pruni Mume, Pericarpium Zanthoxyli Bungeanum, Herba cum Radice Asari, Rhizoma Coptidis, Corex Phellodendri, Rhizoma Zingiberis Officinalis, Radix Lateralis Aconiti Carmichaeli Praeparata, Ramulus Cinnamomi Cassiae, Radix Ginseng, and Radix Angelicae Sinensis.

2. A composition for treating allergies or asthma comprising effective amounts of aqueous extracts of Fructus Pruni Mume, Pericarpium Zanthoxyli Bungeanum, Herba cum Radice Asari, Rhizoma Coptidis, Corex Phellodendri, Rhizoma Zingiberis Officinalis, Radix Lateralis Aconiti Carmichaeli Praeparata, Ramulus Cinnamomi Cassiae, Radix Ginseng, Radix Angelicae Sinensis, and the yeast Ganoderma lucidum.

3. A composition for treating allergies or asthma comprising effective amounts of organic solvent extracts of Fructus Pruni Mume, Pericarpium Zanthoxyli Bungeanum, Herba cum Radice Asari, Rhizoma Coptidis, Corex Phellodendri, Rhizoma Zingiberis Officinalis, Radix Lateralis Aconiti Carmichaeli Praeparata, Ramulus Cinnamomi Cassiae, Radix Ginseng, and Radix Angelicae Sinensis.

4. A composition for treating allergies or asthma comprising effective amounts of organic solvent extracts of Fructus Pruni Mume, Pericarpium Zanthoxyli Bungeanum, Herba cum Radice Asari, Rhizoma Coptidis, Corex Phellodendri, Rhizoma Zingiberis Officinalis, Radix Lateralis Aconiti Carmichaeli Praeparata, Ramulus Cinnamomi Cassiae, Radix Ginseng, Radix Angelicae Sinensis, and Ganoderma lucidum.

5. A composition for treating allergies or asthma comprising effective amounts of ground dried preparations of at least herbs Fructus Pruni Mume, Pericarpium Zanthoxyli Bungeanum, Herba cum Radice Asari, Rhizoma Coptidis, Corex Phellodendri, Rhizoma Zingiberis Officinalis, Radix Lateralis Aconiti Carmichaeli Praeparata, Ramulus Cinnamnomi Cassiae, Radix Ginseng, and Radix Angelicae Sinensis prepared by grinding and drying the herbs.

6. A composition for treating allergies or asthma comprising effective amounts of ground dried preparations of at least herbs Fructus Pruni Mume, Pericarpium Zanthoxyli Bungeanum, Herba cum Radice Asari, Rhizoma Coptidis, Corex Phellodendri, Rhizoma Zingiberis Officinalis, Radix Lateralis Aconiti Carmichaeli Praeparata, Ramulus Cinnamomi Cassiae, Radix Ginseng, Radix Angelicae Sinensis, and yeast Ganoderma lucidum prepared by grinding and drying the herbs and yeast.