Method for solvent bonding polyolefins

• US 6,632,318 B1
• Filed: 09/09/1999
• Issued: 10/14/2003
• Est. Priority Date: 09/09/1999
• Status: Expired due to Fees

• Current Assignee: Baxter International Inc.
• Original Assignee: Baxter International Inc.
• Inventors: Qin, Chuan, Ling, Michael T. K., Woo, Lecon, Ding, Yuan-pang Samuel
• Primary Examiner(s): Johnstone, Adrienne C.
• Application Number:
  US09/393,052
• Time in Patent Office: 1,496 Days
• Field of Search: 156/309.3, 156/308.6
• US Class Current: 156/309.3
• CPC Class Codes: C08L 23/04 Homopolymers or copolymers of ethene
• CPC Class Codes: C08L 23/08 Copolymers of ethene C08L23/16 takes precedence
• CPC Class Codes: C08L 23/0815 Copolymers of ethene with aliphatic 1-olefins
• CPC Class Codes: C08L 23/10 Homopolymers or copolymers of propene
• CPC Class Codes: C08L 23/16 Elastomeric ethene-propene or ethene-propene-diene copolymers, e.g. EPR and EPDM rubbers
• CPC Class Codes: C08L 23/20 having four to nine carbon atoms
• CPC Class Codes: C08L 2666/04 Macromolecular compounds according to groups C08L7/00 - C08L49/00, or C08L55/00 - C08L57/00; Derivatives thereof
• CPC Class Codes: C08L 45/00 Compositions of homopolymers or copolymers of compounds having no unsaturated aliphatic radicals in side chain, and having one or more carbon-to-carbon double bonds in a carbocyclic or in a heterocyclic ring system; Compositions of derivatives of such polymers of cyclic anhydrides or imides C08L35/00; of cyclic esters of polyfunctional acids C08L31/00

Abstract

The present invention provides a method for assembling a medical device using solvent bonding techniques. The method includes the steps of: (1) providing a first article of a polymer composition having (a) a first component of a homopolymer or copolymer obtained using monomers of cyclic olefin or a bridged polycyclic hydrocarbon, the first component being present in an amount from about 30% to about 100% by weight of the composition and (b) a second component from 0-70% by weight of the composition; (2) providing a second article of a material selected from the group of low crystallinity polymers; (3) applying a solvent to one of the first article or the second article to define an interface area; and (4) bonding the first article to the second article along the interface area.

Claims

1. A method for assembling a medical device using solvent bonding techniques comprising the steps of:

providing a first article of a polymer composition comprising

a first component of a homopolymer or copolymer obtained using monomers of cyclic olefin or a bridged polycyclic hydrocarbon by addition polymerization, the copolymer having at least about 20 mole percent of the cyclic olefin monomer or the bridged polycyclic hydrocarbon monomer, the first component being present in an amount from about 30% to about 99% by weight of the composition, and a second component in an amount from about 1% to about 70% by weight of the composition;

providing a second polymeric article of a material selected from the group consisting of low crystallinity polymers;

applying a solvent to one of the first article or the second article to define an interface area; and

bonding the first article to the second article along the interface area.

2. The method of claim 1 wherein the cyclic olefins have from 5 to about 10 carbons in the ring.

3. The method of claim 2 wherein the cyclic olefins are selected from the group consisting of substituted and unsubstituted cyclopentene, cyclopentadiene, cyclohexene, cyclohexadiene, cycloheptene, cycloheptadiene, cyclooctene, and cyclooctadiene.

4. The method of claim 1 wherein the bridged polycyclic hydrocarbon has at least 7 carbons.

5. The method of claim 4 wherein the bridged polycyclic hydrocarbon is norbornene.

6. The method of claim 1 wherein the first component is obtained by copolymerizing the cyclic olefin or the bridged polycyclic hydrocarbon with a comonomer.

7. The method of claim 6 wherein the comonomer is selected from the group consisting of α

-olefins having from 2-10 carbons, aromatic hydrocarbons, cyclic olefins, and bridged polycyclic hydrocarbons.

8. The method of claim 7 wherein the first component is a copolymer of a norbornene monomer and an ethylene monomer.

9. The method of claim 8 wherein the norbornene is present from about 30 to about 60 mole percent.

10. The method of claim 9 wherein the glass transition temperature of the first component is from about 70°

C. to about 180°

C.

11. The method of claim 8 wherein the first article is a medical housing.

12. The method of claim 1 wherein the second article is a medical tubing of a polyolefin.

13. The method of claim 1 wherein the first article has a second component of a polymer selected from the group consisting of homopolymers and copolymers of ethylene, propylene, butene, hexene, octene, nonene, decene and styrene.

14. The method of claim 13 wherein the second component is an ethylene and α

-olefin copolymer.

15. The method of claim 14 wherein the low crystallinity polymer is selected from the group consisting of cyclic olefin containing polymers (COCs), COC blends having minimally 30% COC by weight, polymethyl pentene, polyolefins having a modulus of elasticity of less than 10,000 psi, and styrene containing polymers without modulus limitations.

16. The method of claim 15 wherein the low crystallinity polymer is a homopolymer or copolymer of ethylene.

17. The method of claim 16 wherein the copolymers of ethylene are selected from the group consisting of (a) ethylene copolymerized with monomers selected from the group of α

-olefins having 3-10 carbons, lower alkyl and lower alkene substituted carboxylic acids and ester and anhydride derivatives thereof, (b) ethylene-propylene rubbers, (c) ethylene-propylene-diene monomer (EPDM), and (d) ionomers.

18. The method of claim 17 wherein the second article is selected from the group consisting of an ultra low density polyethylene and ethylene and vinyl acetate copolymer.

19. The method of claim 18 wherein the ultra low density polyethylene is obtained using a metallocene catalyst.

20. The method of claim 18 wherein the ethylene vinyl acetate copolymer has a vinyl acetate content from 5% to about 32%.

21. The method of claim 14 further comprising a third component of a homopolymer or copolymer obtained using a monomer selected from the group consisting of cyclic olefins and a bridged polycyclic hydrocarbons.

22. The method of claim 21 wherein the first component has a glass transition temperature of lower than 120°

C. and the third component has a glass transition temperature higher than about 120°

C.

23. The method of claim 22 wherein the third component is present in an amount from 10% to about 90% by weight of the composition.

24. The method of claim 23 wherein the first component and second component are present in a ratio of from about 2:

1 to about 1;

2 by weight.

25. The method of claim 1 wherein the second article is of an ultra low density polyethylene.

26. The method of claim 1 wherein the second article is of an ethylene and vinyl acetate copolymer.

27. The method of claim 1 wherein the solvent has a solubility parameter of less than 20 (MPa)^½

and having a molecular weight less than about 200 g/mole.

28. The method of claim 27 wherein the solvent is selected from the group cosisting of aliphatic hydrocarbons, aromatic hydrocarbons, mixtures of aliphatic hydrocarbons, mixtures of aromatic hydrocarbons and mixtures of aromatic and aliphatic hydrocarbons.

29. The method of claim 28 wherein the aliphatic hydrocarbon is selected from the group consisting of substituted and unsubstituted hexane, heptane, cyclohexane, cycloheptane, and decalin.

30. The method of claim 28 wherein the aromatic hydrocarbon is selected from the group consisting of substituted and unsubstituted xylene, tetralin, toluene, and cumene.

31. A method for assembling a medical device using solvent bonding techniques comprising the steps of:

providing a first article of a polymer composition comprising

a first component obtained by copolymerizing a norbomene monomer and an ethylene monomer through addition polymerization, the norbornene monomer being present in an amount of at least about 20 mole percent of the copolymer, the first component being present in an amount from about 30% to about 99% by weight of the composition; and

a second component of a first ethylene and α

-olefin copolymer, the second component being in an amount from about 70% to about 1% by weight of the composition;

providing a second article of a low crystallinity polymer;

applying a solvent to one of the first article or the second article to define an interface area; and

bonding the first article to the second article along the interface area.

32. The method of claim 31 wherein the first component has from about 30 to about 60 mole percent norbornene monomer.

33. The method of claim 31 wherein the glass transition temperature of the first component is from about 70°

C. to about 180°

C.

34. The method of claim 31 wherein the low crystallinity polymer is selected from the group consisting of cyclic olefin containing polymers (COCs), COC blends having minimally 30% COC by weight, polymethyl pentene, polyolefins having a modulus of elasticity of less than 10,000 psi, and styrene containing polymers without modulus limitations.

35. The method of claim 34 wherein the low crystallinity polymer is a homopolymer or copolymer of ethylene.

36. The method of claim 35 wherein the copolymers of ethylene are selected from the group consisting of (a) ethylene copolymerized with monomers selected from the group of α

-olefins having 3-10 carbons, lower alkyl and lower alkene substituted carboxylic acids and ester and anhydride derivatives thereof, (b) ethylene-propylene rubbers, (c) ethylene-propylene-diene monomer (EPDM), and (d) ionomers.

37. The method of claim 36 wherein the second article is selected from the group consisting of an ultra low density polyethylene and ethylene and vinyl acetate copolymer.

38. The method of claim 37 wherein the ultra low density polyethylene is obtained using a metallocene catalyst.

39. The method of claim 37 wherein the ethylene vinyl acetate copolymer has a vinyl acetate content from 5% to about 32%.

40. The method of claim 31 wherein the second article is of an ultra low density polyethylene.

41. The method of claim 31 wherein the second article is of an ethylene and vinyl acetate copolymer.

42. The method of claim 31 further comprising a third component of a homopolymer or copolymer obtained using a monomer selected from the group consisting of a cyclic olefin and a bridged polycyclic hydrocarbon.

43. The method of claim 42 wherein the third component has a glass transition temperature of higher than 120°

C. and the first component has a glass transition temperature lower than 120°

C.

44. The method of claim 42 wherein the third component is present in an amount from 10% to about 90% by weight of the composition.

45. The method of claim 44 wherein the first component and second component are present in a ratio of from about 2:

1 to about 1;

2 by weight.

46. The method of claim 31 wherein the first article is a medical housing.

47. The method of claim 46 wherein the second article is a medical tubing of a polyolefin.

48. The method of claim 31 wherein the solvent has a solubility parameter of less than 20 (MPa)^½

and a molecular weight of less than about 200 g/mole.

49. The method of claim 48 wherein the solvent is selected from the group consisting of aliphatic hydrocarbons, aromatic hydrocarbons, mixtures of aliphatic hydrocarbons, mixtures of aromatic hydrocarbons and mixtures of aromatic and aliphatic hydrocarbons.

50. The method of claim 49 wherein the aliphatic hydrocarbon is selected from the group consisting of substituted and unsubstituted hexane, heptane, octane, cyclooctane, cyclohexane, cycloheptane, and decalin.

51. The method of claim 49 wherein the aromatic hydrocarbon is selected from the group consisting of substituted and unsubstituted xylene, tetralin, toluene, and cumene.