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Microanalytical device and use thereof for conducting chemical processes

  • US 6,635,226 B1
  • Filed: 02/11/2000
  • Issued: 10/21/2003
  • Est. Priority Date: 10/19/1994
  • Status: Expired due to Term
First Claim
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1. A microanalytical device in which chemical and biochemical reactions can be conducted, comprising:

  • a substrate fabricated from materials that are not silicon based, said substrate having first and second substantially planar opposing surfaces, and said substrate having a cavity and at least one microchannel formed in the first planar surface, wherein the cavity serves as a reaction zone that is in fluid communication with each microchannel;

    a cover plate arranged over the first planar surface, said cover plate in combination with the cavity defining a reaction chamber, and with each microchannel defining a microcolumn; and

    at least one inlet port and at least one outlet port communicating directly or indirectly with the reaction chamber, said ports enabling the passage of fluid from an external source into and through the reaction chamber, thereby defining a fluid flow path;

    wherein a surface of the reaction chamber and/or the microcolumn is coated with or functionalized to contain a polyether.

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