Process for the preparation of hydroxylated lecithin from crude soybean lecithin

• US 6,638,544 B2
• Filed: 03/25/2002
• Issued: 10/28/2003
• Est. Priority Date: 03/25/2002
• Status: Active Grant

• Current Assignee: Council of Scientific & Industrial Research
• Original Assignee: Council of Scientific & Industrial Research
• Inventors: Prasad, Rachapudi Badari Narayana, Karuna, Marellapudi Sri Lakshmi, Vandana, Vemulapalli, Prasad, Potharaju Seetharamanjaneya Sai
• Primary Examiner(s): Lankford, Jr., Leon B.
• Assistant Examiner(s): Coe, Susan D
• Application Number:
  US10/105,965
• Publication Number:
  US 20030180403A1
• Time in Patent Office: 582 Days
• Field of Search: 424/757, 424/725
• US Class Current: 424/757
• CPC Class Codes: A61K 36/48 Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae

Abstract

The invention relates to a microwave assisted process for the preparation of hydroxylated lecithin from soybean lecithin comprising hydroxylating crude soybean lecithin by using hydrogen peroxide and lactic acid as hydroxylating agent through microwave irradiation.

Claims

1. A process for preparation of hydroxylated lecithin from soybean lecithin, which comprises treating said soybean lecithin with from about 1 to 4% by weight of a 30% hydrogen peroxide solution based on the weight of lecithin and from about 12 to 18% by weight of a 75% lactic acid solution based on the weight of lecithin while subjecting the mixture of lecithin, hydrogen peroxide, and lactic acid to microwave irradiation at a power of from about 300 to 600 W at a temperature of from about 50 to 70°

C. for a period of from about 5 to 60 minutes to obtain the desired product.

2. A process as claimed in claim 1, wherein the amount of hydrogen peroxide used in the reaction mixture is preferably 3% of lecithin.

3. A process as claimed in claim 1, wherein the amount of lactic acid peroxide used in the reaction mixture is preferably 15% of lecithin.

4. A process as claimed in claim 1, wherein the reaction is carried out for a period in the range of 5-40 min.

5. A process as claimed in claim 1 wherein the reduction of iodine value in hydroxylated lecithin is about 20 to 37%.