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Vessel, preferably spherical or oblate spherical for growing or culturing cells, cellular aggregates, tissues and organoids and methods for using same

  • US 6,642,019 B1
  • Filed: 11/22/2000
  • Issued: 11/04/2003
  • Est. Priority Date: 11/22/2000
  • Status: Expired due to Term
First Claim
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1. A culture vessel comprising:

  • a housing defining a chamber having at least one inlet and at least one outlet, the housing adapted to rotate about a longitudinal substantially horizontal axis;

    at least one filter within the chamber in fluid communication with an outlet, the filter having openings of a size that allows the passage of a fluid culture medium and cellular metabolic waste but prevents the passage of cells and cellular aggregates;

    the chamber having a substantially unobstructed horizontal axis; and

    a pump in fluid communication with at least one of an inlet or an outlet, wherein the chamber is symmetrical about an axis.

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