Meter and method of using the meter for determining the concentration of a component of a fluid
First Claim
1. An apparatus for determining the concentration of a medically significant component of a biological fluid, the apparatus comprising a cell for receiving a sample of the fluid, the cell supporting a chemistry which reacts with the medically significant component and first and second terminals across which the reaction of the chemistry with the medically significant component can be assessed, an instrument having first and second terminals complementary to the first and second terminals, respectively, of the cell, placement of the first and second terminals of the cell in contact with the first and second terminals, respectively, of the instrument permitting the instrument to assess the reaction, the instrument including an assessment controller configured to apply across the first and second terminals of the instrument a first signal having an AC component, to determine a first correction value in response of the cell to the first signal, to assess the reaction of the medically significant component with the chemistry and to combine the correction value with the result of the reaction assessment to produce an indication of the concentration of the medically significant component in the sample.
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Accused Products
Abstract
An apparatus and method for determining the concentration of a medically significant component of a biological fluid comprise providing a cell supporting a chemistry which reacts with the medically significant component. Placement of first and second terminals of the cell in contact with first and second terminals, respectively, of an instrument permits the instrument to assess the reaction. The instrument determines a first response of the cell to a first signal, and determines based upon the first response whether to proceed with the determination of the concentration of the medically significant component of the biological fluid. If the determination is to proceed, the instrument determines the type of sample that has been applied. If the sample is a sample of a particular type, the instrument determines a first correction value based upon the cell'"'"'s response to the third signal and combines the correction value with the result of the reaction assessment to produce an indication of the concentration of the medically significant component in the sample.
389 Citations
46 Claims
- 1. An apparatus for determining the concentration of a medically significant component of a biological fluid, the apparatus comprising a cell for receiving a sample of the fluid, the cell supporting a chemistry which reacts with the medically significant component and first and second terminals across which the reaction of the chemistry with the medically significant component can be assessed, an instrument having first and second terminals complementary to the first and second terminals, respectively, of the cell, placement of the first and second terminals of the cell in contact with the first and second terminals, respectively, of the instrument permitting the instrument to assess the reaction, the instrument including an assessment controller configured to apply across the first and second terminals of the instrument a first signal having an AC component, to determine a first correction value in response of the cell to the first signal, to assess the reaction of the medically significant component with the chemistry and to combine the correction value with the result of the reaction assessment to produce an indication of the concentration of the medically significant component in the sample.
- 11. An apparatus for determining the concentration of a medically significant component of a biological fluid, the apparatus comprising a cell for receiving a sample of the fluid, the cell supporting a chemistry which reacts with the medically significant component and first and second terminals across which the reaction of the chemistry with the medically significant component can be assessed, an instrument having first and second terminals complementary to the first and second terminals, respectively, of the cell, placement of the first and second terminals of the cell in contact with the first and second terminals, respectively, of the instrument permitting the instrument to assess the reaction, the instrument including an assessment controller configured to apply across the first and second terminals of the instrument a first signal having an AC component, determine a first response of the cell to the first signal, and determine based upon the first response whether to proceed with the determination of the concentration of the medically significant component of the biological fluid.
- 22. A method for determining the concentration of a medically significant component of a biological fluid, the method comprising providing a cell for receiving a sample of the fluid, providing on the cell a chemistry which reacts with the medically significant component and first and second terminals across which the reaction of the chemistry with the medically significant component can be assessed, providing an instrument having first and second terminals complementary to the first and second terminals, respectively, of the cell, placement of the first and second terminals of the cell in contact with the first and second terminals, respectively, of the instrument permitting the instrument to assess the reaction, including in the instrument an assessment controller, causing the assessment controller to apply across the first and second terminals of the instrument a first signal having an AC component, causing the assessment controller to determine a first response of the cell to the first signal, and causing the assessment controller to determine based upon the first response whether to proceed with the determination of the concentration of the medically significant component of the biological fluid.
- 31. A method for determining the concentration of a medically significant component of a biological fluid, the method comprising providing a cell for receiving a sample of the fluid, providing the cell with a chemistry which reacts with the medically significant component and first and second terminals across which the reaction of the chemistry with the medically significant component can be assessed, providing an instrument having first and second terminals complementary to the first and second terminals, respectively, of the cell, placement of the first and second terminals of the cell in contact with the first and second terminals, respectively, of the instrument permitting the instrument to assess the reaction, providing in the instrument an assessment controller, causing the assessment controller to apply across the first and second terminals of the instrument a first signal having an AC component, determining a first correction value in response to the first signal, assessing the reaction of the medically significant component with the chemistry, and combining the correction value with the result of the reaction assessment to produce an indication of the concentration of the medically significant component in the sample.
- 39. An apparatus for determining the concentration of a medically significant component of a biological fluid comprising a cell for receiving a sample of the fluid, the cell supporting a chemistry which reacts with the medically significant component and first and second terminals across which the reaction of the chemistry with the medically significant component can be assessed, an instrument having first and second terminals complementary to the first and second terminals, respectively, of the cell, placement of the first and second terminals of the cell in contact with the first and second terminals, respectively, of the instrument permitting the instrument to assess the reaction, the instrument including an assessment controller configured to apply across the first and second terminals of the instrument a first signal having an AC component, determine the identity of the sample in response of the cell to the first signal, and produce an indication of the identity of the sample.
- 44. A method for determining the concentration of a medically significant component of a biological fluid comprising providing a cell for receiving a sample of the fluid, providing on the cell a chemistry which reacts with the medically significant component and first and second terminals across which the reaction of the chemistry with the medically significant component can be assessed, providing an instrument having first, second and third terminals, placement of the first and second terminals of the cell in contact with the first and second terminals of the instrument, providing in the instrument an assessment controller configured to apply across the first and second terminals of the instrument a first signal, determine the identity of the sample in response of the cell to the first signal, the assessment controller applying across a pair of the first, second and third terminals of the instrument a second signal, determining a first correction value in response of the cell to the second signal, assessing the reaction of the medically significant component with the chemistry, and combining the correction value with the result of the reaction assessment to produce an indication of the concentration of the medically significant component in the sample.
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46. A method for determining the concentration of a medically significant component of a biological fluid comprising providing a cell for receiving a sample of the fluid, providing on the cell a chemistry which reacts with the medically significant component and first and second terminals across which the reaction of the chemistry with the medically significant component can be assessed, providing an instrument having first, second and third terminals, placement of the first and second terminals of the cell in contact with the first and second terminals of the instrument placing one of the first and second terminals of the cell in contact with the third terminal of the instrument, providing in the instrument an assessment controller configured to apply across the first and second terminals of the instrument a first signal, determine the identity of the sample in response of the cell to the first signal, and produce an indication of the identity of the sample, the assessment controller applying across a pair of the first, second and third terminals of the instrument a second signal and determining a second response to the second signal, the second response determining if the assessment controller proceeds with the application of the first signal.
Specification