Inhaler for powdered medicaments

• US 6,648,848 B1
• Filed: 01/12/2000
• Issued: 11/18/2003
• Est. Priority Date: 05/27/1997
• Status: Expired due to Term

• Current Assignee: Acerus Biopharma, Inc.
• Original Assignee: Direct-Haler A/S (Keldmann Innovation A/S)
• Inventors: Ouesada, Jorge Martinez, Keldmann, Erik, Keldmann, Troels, Pelaez, Ricardo Palacios
• Primary Examiner(s): Walberg, Teresa
• Assistant Examiner(s): ROBINSON, DANIEL LEON
• Application Number:
  US09/424,085
• Time in Patent Office: 1,406 Days
• Field of Search: 604/57, 604/58, 604/59, 604/60, 604/61, 604/62, 604/63, 604/64, 604/48, 128/203.15, 128/203.16, 128/203.17, 128/203.18, 128/203.19, 128/203.2, 128/203.21, 128/203.22, 128/203.23
• US Class Current: 604/57
• CPC Class Codes: A61M 15/0098 Activated by exhalation
• CPC Class Codes: A61M 15/08 Inhaling devices inserted into the nose
• CPC Class Codes: A61M 2202/064 Powder
• CPC Class Codes: A61M 2210/0625 Mouth

Abstract

A method and device for introducing a powdered or particulate substance into a person'"'"'s nostril

A device for applying a powdered or particulate substance to a mucous membrane in a nostril comprises a tubular body (10) similar to a drinking straw. The tubular body has opposite end parts forming a mouthpiece (11) and a nasal piece (12) to be inserted between the lips and into the nostril, respectively, of a user. The mouthpiece (11) and the nasal piece (12) are interconnected by a bent or a bendable, preferably corrugated part (13). A dose of a powdered or particulate substance arranged within the tubular body (10) is transferred to the nostril when the user blows into the mouthpiece (11). A part of the mouthpiece is preferably deflated or compresses between a pair of fingers (35) of the user. The compressed part (34) is released when the user has started to blow forcefully into the compressed mouthpiece part which is thereby inflated. It has been found that the user will automatically close the connection between the nostrils and the throat by the uvula when blowing.

Claims

1. A device for applying a powdered or particulate substance to a mucous membrane within a nostril of a user of the device, said device comprising:

a tubular body having;

an intermediate bend and/or bendable section composed of adjacent, peripherally extending corrugations with the corrugations having a substantially serrated outline when viewed in a longitudinal axial section, the tubular body defining

an inner flow passage with a cross-sectional area not exceeding 75 mm² extending longitudinally between a nasal piece at a first end of the tubular body to be inserted into the nostril of the user and an opposite second end of said body,

wherein the second end of the tubular body defines a mouthpiece to be inserted between the lips of the user, the length and the shape of the tubular body being such that the nasal piece and the mouthpiece may at the same time be positioned into the nostril and between the lips, respectively, of the user, whereby the user may blow into the mouthpiece end of the flow passage and transfer powdered or particulate substance arranged within the flow passage of the tubular body to the nostril in a dispensed condition.

2. A device according to claim 1, further comprising:

a dose of a powdered or particulate substance arranged within the flow passage.

3. A device according to claim 2, wherein the powdered or particulate substance is as substance active against allergy.

4. A device according to claim 1, wherein the cross-sectional areas of the flow passage do not exceed 70 mm².

5. A device according to claim 4, wherein the cross-sectional areas of the flow passage do not exceed 50 mm².

6. A device according to claim 5, wherein the cross-sectional areas of the flow passage are 7-35 mm².

7. A device according to claim 6, wherein the cross-sectional areas of the flow passage are about 20 mm².

8. A device for applying a powdered or particulate substance to a mucous membrane within a nostril of a user of the device, said device comprising:

a tubular body having;

a mouthpiece at a first end to be inserted between the lips of the user; and

a nasal piece at an opposite second end to be inserted into the nostril, with the tubular body further defining;

an inner flow passage extending longitudinally between the mouthpiece and the nasal piece, whereby the user may blow into the mouthpiece end of the flow passage and transfer the powdered or particulate substance arranged within the flow passage of the tubular body to the nostril in a dispensed condition;

wherein the tubular body also comprises;

an intermediate bent and/or bendable section wherein the bent and/or bendable section comprises;

adjacent, peripherally extending corrugations, said corrugations having a substantially serrated outline when viewed in a longitudinal, axial section, the flow passage of the tubular body having a cross-sectional area not exceeding 75 mm²;

wherein said device further comprises;

restriction means.