Inflatable catheter for selective organ heating and cooling and method of using the same

• US 6,648,908 B2
• Filed: 03/11/2002
• Issued: 11/18/2003
• Est. Priority Date: 01/23/1998
• Status: Expired due to Term

• Current Assignee: Zoll Circulation Incorporated (Asahi Kasei Corporation)
• Original Assignee: Innercool therapies Incorporated (Taxus Cardium Pharmaceuticals Group, Inc.)
• Inventors: Lasheras, Juan C., Dobak, John D. III
• Primary Examiner(s): ROLLINS, ROSILAND STACIE
• Application Number:
  US10/096,294
• Publication Number:
  US 20020103519A1
• Time in Patent Office: 617 Days
• Field of Search: 128/898, 607/96, 607/104, 607/105, 607/106, 607/113, 606/20-24
• US Class Current: 607/105
• CPC Class Codes: A61B 18/02 by cooling, e.g. cryogenic techniques devices for cooling specific reflex points of the body within cell-life limits A61H39/06
• CPC Class Codes: A61B 2017/00292 mounted on or guided by flexible, e.g. catheter-like, means
• CPC Class Codes: A61B 2018/0022 Balloons
• CPC Class Codes: A61B 2018/0212 using an instrument inserted into a body lumen, e.g. catheter
• CPC Class Codes: A61B 2018/0262 using a circulating cryogenic fluid
• CPC Class Codes: A61F 2007/0056 for cooling
• CPC Class Codes: A61F 2007/126 for invasive application, e.g. for introducing into blood vessels
• CPC Class Codes: A61F 7/12 Devices for heating or cooling internal body cavities

Abstract

A catheter system and method are provided which change the temperature of a fluid, such as blood, by heat transfer. Selective cooling or heating of an organ may be performed by changing the temperature of the blood feeding the organ. The catheter system includes an inlet lumen and an outlet lumen structured and arranged to carry a working fluid having a temperature different from the adjacent blood. The outlet lumen is configured to induce turbulence in the adjacent fluid passing adjacent the outlet lumen.

Claims

1. A method for selectively cooling or heating an organ in a body of a patient, comprising:

introducing a catheter having an inflatable heat transfer element formed by at least an inlet lumen and an outlet lumen, the inlet lumen configured to provide working fluid to the heat transfer element and the outlet lumen configured to remove working fluid from the heat transfer element, into an artery supplying the organ, at least one of the inlet lumen or the outlet lumen having a helical shape to induce turbulence in blood flowing in the artery;

inflating the heat transfer element; and

inducing free stream turbulence in blood flowing over the at least one of the inlet lumen or the outlet lumen having a helical shape;

such that heat is removed from or added to the blood to cool or heat the organ.

2. A method for selectively cooling an organ in a body of a patient, comprising:

introducing a catheter having an inflatable heat transfer element, formed by at least an inlet lumen and an outlet lumen, the outlet lumen having a helical turbulence-inducing path, into a blood vessel supplying the organ;

circulating a working fluid through the heat transfer element, wherein the working fluid is removed from the heat transfer element by passing through the helical turbulence-inducing path of the outlet lumen, the working fluid having a temperature less than the temperature of the blood vessel; and

inducing free stream turbulence in blood flowing over the outlet lumen of the heat transfer element;

such that heat is removed from the blood to cool the organ.