Guidewire-access modular intraluminal prosthesis with connecting section

• US 6,648,913 B1
• Filed: 06/07/1999
• Issued: 11/18/2003
• Est. Priority Date: 06/07/1999
• Status: Expired due to Term

• Current Assignee: Lifeshield Sciences LLC (Acacia Research Corporation)
• Original Assignee: Scimed Life Systems Incorporated (Boston Scientific Corporation)
• Inventors: Nun̅ez, José F., Yee, Carl E., Staudenmeier, Marianne W.
• Primary Examiner(s): Snow, Bruce
• Assistant Examiner(s): Pellegrino, Brian E
• Application Number:
  US09/327,069
• Time in Patent Office: 1,625 Days
• Field of Search: 623/1.13, 623/1.15, 623/1.16, 623/1.18, 623/1.2, 623/1.23, 623/1.31, 623/1.34, 623/1.35, 623/1.44
• US Class Current: 623/1.35
• CPC Class Codes: A61F 2/064 with special features to facilitate anastomotic coupling anastomosis of natural blood vessels A61B17/11
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/89 the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2002/067 modular
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2250/0039 differing in diameter

Abstract

A multi-component intraluminal prosthesis is adapted for insertion into and in vivo assembly within a body lumen to repair the lumen, the components including secure and/or fluid-tight mating sections. The prosthesis comprises a female mating member comprising a main body portion, a funnel-shaped end, and a sealing segment connecting the main body portion to the funnel-shaped end; and a male mating member adapted for in vivo assembly with the sealing segment of the female mating member. The sealing segment may be essentially cylindrical or it may taper with decreasing diameter from the main body to the funnel-shaped end. The sealing segment and adjacent funnel-shaped end may together form an hourglass-shaped end. A biocompatible graft material may cover the inner surface of the funnel-shaped end. To secure a fluid-tight seal, the outer surface of the male member and the inner surface of the female member are covered with a biocompatible graft material in their respective mating segments. The prosthesis may form a bifurcated intraluminal prosthesis adapted, for example, for deployment in the infra-renal aorta and the iliac arteries, where the main body component forms the main aortic body, the integral first leg member forms the first iliac segment, and the second leg member forms the second iliac segment.

Claims

1. An intraluminal modular prosthesis comprising:

a pair of tubular mating members comprising a female mating member and a male mating member adapted for in vivo assembly securely with one another, the pair of tubular mating members having an assembled configuration and a disassembled configuration;

the female mating member comprising a main body and at least one depending member having a funnel-shaped end and a connecting segment that tapers with decreasing diameter from the main body to the funnel-shaped end along a first axial length, the funnel-shaped end flaring with increasing diameter from the connecting segment along a second axial length, the connecting segment and adjacent funnel-shaped end together forming an hourglass-shaped end;

the male mating member comprising an hourglass-shaped end in both the disassembled configuration and the assembled configuration, the hourglass-shaped end in the assembled configuration comprising a tapered section adapted to contact the female mating member connecting segment and a flared section adapted to contact the female mating member funnel-shaped end all along the second axial length;

the hourglass-shaped ends of the female mating member and the male mating member adapted to self-lock with one another in the assembled configuration to form a tight seal.

2. The prosthesis of claim 1, wherein said prosthesis has a first compressed configuration for introducing said prosthesis into the body lumen, and a second expanded configuration for deployment of said prosthesis within the body lumen.

3. The prosthesis of claim 2 wherein the prosthesis is adapted to be converted from the compressed configuration to the expanded configuration by a mechanism selected from the group consisting of:

balloon expansion, shape memory material self-expansion, and elastic self-expansion.

4. The prosthesis of claim 1 further comprising a biocompatible graft material covering one or both of an inner mating surface of the connecting segment and an outer mating surface of the male mating member adapted for contact with said connecting segment.

5. The prosthesis of claim 1 wherein a biocompatible graft material covers an inner surface of the funnel-shaped end.

6. The prosthesis of claim 5 wherein said biocompatible graft material also covers an inner surface of the connecting segment.

7. The prosthesis of claim 6 wherein said biocompatible graft material also covers at least a portion of the outside of said female mating member.

8. The prosthesis of claim 6 wherein an outer surface of at least a mating section of said male member is covered with said biocompatible graft material.

9. The prosthesis of claim 1 wherein a biocompatible graft material covers (a) an outer surface of all of said prosthesis except for one or more anchoring ends adapted to allow tissue growth thereabout once deployed within said body lumen and, optionally, said funnel-shaped end, and (b) an inner surface of said funnel-shaped end.

10. The prosthesis of claim 1 wherein the prosthesis is branched into at least two extensions depending from said main body section, wherein at least one of said extensions comprises an integral female mating member and said connecting segment.

11. The prosthesis of claim 10 wherein at least one of said extensions comprises an integral first leg member that depends from said bifurcation alongside said integral female mating member.

12. The prosthesis of claim 11 wherein the male mating member comprises a second leg member.

13. The prosthesis of claim 1, wherein the prosthesis comprises a bifurcated aortic intraluminal prosthesis adapted for deployment in the infra-renal aorta and the iliac arteries.

14. A bifurcated intraluminal modular prosthesis adapted for insertion into and assembly within a bifurcated body lumen to repair the lumen, said prosthesis comprising a pair of tubular mating members comprising a female mating member and a male mating member adapted for in vivo assembly securely with one another, the pair of tubular mating members having an assembled configuration and a disassembled configuration;

the female mating member comprising a main body and at least one depending member having a funnel-shaped end and a connecting segment that tapers with decreasing diameter from the main body to the funnel-shaped end along a first axial length, the funnel-shaped end flaring with increasing diameter from the connecting segment along a second axial length, the connecting segment and adjacent funnel-shaped end together forming an hourglass-shaped end, the female mating member having an outer surface covered with a biocompatible graft material except for one or more anchoring ends and, optionally, said funnel-shaped end, said funnel-shaped end having an inner mating surface covered with said biocompatible graft material;

the male mating member comprising an hourglass-shaped end in both the disassembled configuration and the assembled configuration, the hourglass-shaped end in the assembled configuration comprising a tapered section adapted to contact the female mating member connecting segment and a flared section adapted to contact the female mating member funnel-shaped end all along the second axial length, the male mating member having an outer surface covered with said biocompatible graft material;

the hourglass-shaped ends of the female mating member and the male mating member adapted to self-lock with one another in the assembled configuration to form a tight seal.

15. An intraluminal prosthesis adapted for insertion from a distal location into and assembly within a body lumen to repair the lumen in a proximal location, said prosthesis comprising a pair of tubular mating members comprising a female mating member and a male mating member adapted for in vivo assembly securely with one another, the pair of tubular mating members having an assembled configuration and a disassembled configuration;

the female mating member comprising a main body portion that branches into at least two depending members, each depending member having an external diameter, at least one of said depending members having a funnel-shaped end and having a connecting segment having a defined axial length connecting said main body portion to said funnel-shaped end, the funnel-shaped end having a diameter that increases distally in a first slope and the connecting segment having a diameter that decreases distally in a second slope, the funnel-shaped end and the connecting segment together forming a female interface for receiving the male mating member;

the male mating member comprising in both the disassembled configuration and the assembled configuration a flared section having a diameter that increases distally and a tapered section having a diameter that decreases distally, the flared section and the tapered section together forming a male interface for connection with the female interface, the flared section in the assembled configuration adapted to contact the female mating member funnel shaped end and having the first slope and the tapered section in the assembled configuration adapted to contact the female mating member connecting segment and having the second slope;

the female interface and the male interface adapted to self-lock with one another in the assembled configuration to form a tight seal.

16. The intraluminal prosthesis of claim 15, wherein the prosthesis is a bifurcated prosthesis adapted for insertion into and assembly within a bifurcated body lumen to repair the lumen;

said female mating member having an outer surface covered with a biocompatible graft material except for one or more anchoring ends and, optionally, said funnel-shaped end, said funnel-shaped end having an inner mating surface covered with said biocompatible graft material; and

said male mating member having an outer surface covered with said biocompatible graft material.