Human proteases and polynucleotides encoding the same

• US 6,649,399 B2
• Filed: 12/08/2000
• Issued: 11/18/2003
• Est. Priority Date: 12/09/1999
• Status: Expired due to Fees

• Current Assignee: Lexicon Genetics, Incorporated
• Original Assignee: Lexicon Genetics, Incorporated
• Inventors: Sands, Arthur T., Zambrowicz, Brian, Scoville, John, Friedrich, Glenn, Donoho, Gregory, Turner, C. Alexander Jr.
• Primary Examiner(s): Prouty, Rebecca E.
• Assistant Examiner(s): Walicka, Malgorzata A.
• Application Number:
  US09/963,791
• Publication Number:
  US 20020120113A1
• Time in Patent Office: 1,075 Days
• Field of Search: 435/219, 435/226, 435/320.1, 435/325, 435/252.3, 435/254.2, 536/23.2, 536/24.33
• US Class Current: 435/252.3
• CPC Class Codes: C12N 9/6489 Metalloendopeptidases (3.4.24)

Abstract

Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.

Claims

1. An isolated nucleic acid molecule comprising the nucleotide sequence shown in SEQ ID NO:

1.

2. An isolated nucleic acid molecule comprising a nucleotide sequence that:

(a) encodes the amino acid sequence shown in SEQ ID NO;

2; and

(b) hybridizes under stringent conditions with wash conditions of 0.1×

SSC/0.1% SDS at 68°

C. to the nucleotide sequence of SEQ ID NO;

1 or the complement thereof.

3. An isolated nucleic acid molecule encoding the amino acid sequence described in SEQ ID NO:

2.

4. An expression vector comprising a nucleic acid sequence of claim 3.

5. A cell comprising the expression vector of claim 4.