Tissue heating and ablation systems and methods which predict maximum tissue temperature

• US 6,652,513 B2
• Filed: 09/24/2001
• Issued: 11/25/2003
• Est. Priority Date: 06/07/1995
• Status: Expired due to Fees

• Current Assignee: EP Technology (Boston Scientific Corporation)
• Original Assignee: EP Technology (Boston Scientific Corporation)
• Inventors: Panescu, Dorin, Swanson, David K., Fleischman, Sidney D.
• Primary Examiner(s): Shay, David M.
• Application Number:
  US09/962,662
• Publication Number:
  US 20030055419A1
• Time in Patent Office: 792 Days
• Field of Search: 606/34-52, 607/94, 607/102
• US Class Current: 606/34
• CPC Class Codes: A61B 18/1206 Generators therefor
• CPC Class Codes: A61B 18/1402 Probes for open surgery
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2018/00083 low, i.e. electrically insulating
• CPC Class Codes: A61B 2018/00095 high, i.e. heat conducting
• CPC Class Codes: A61B 2018/00791 Temperature
• CPC Class Codes: A61B 2018/00803 with temperature prediction
• CPC Class Codes: A61N 1/403 for thermotherapy, e.g. hyperthermia

Abstract

Systems and methods heat or ablate body tissue by positioning an electrode to transmit heat or ablation energy to a tissue region. The systems and methods measure a first temperature using a temperature sensing element associated with the electrode. The systems and methods also measure a second temperature using a temperature sensing element associated with the electrode. The systems and methods process at least one of the first and second temperatures to derive a prediction of maximum temperature of the tissue region. The systems and methods generate an output that controls the transmission of the heating or ablation energy based, at least in part, upon the maximum tissue temperature prediction.

Claims

1. A method of predicting a maximum temperature of body tissue to be heated, comprising:

placing an electrode adjacent the body tissue to create an electrode-tissue interface;

heating the thermal mass of the electrode to determine an electrode-tissue interface characterization indicator;

transmitting RF heating energy to the electrode and measuring first and second temperatures at the electrode-tissue interface; and

determining a maximum predicted tissue temperature based at least in part on the determined electrode-tissue interface characterization indicator and the first and second measured temperatures.

2. The method of claim 1, wherein the electrode is placed in contact with the body tissue.

3. The method of claim 1, wherein the electrode-tissue interface characterization indicator comprises one of heat loss and spatial temperature gradient of the electrode.

4. The method of claim 1, wherein the electrode-tissue interface characterization indicator is indicative of one or more of the thermal conductivity, density, and heat capacity of the electrode, the amount of electrical and thermal contact between the tissue and the electrode, and the convective cooling induced by a flow of liquid along the body tissue.

5. The method of claim 1, wherein the maximum predicted tissue temperature is determined by comparing the electrode-tissue interface characterization indicator and the first and second measured temperatures to a look-up table that correlates experimentally measured data with an experimentally measured maximum tissue temperature.

6. The method of claim 1, further comprising comparing the maximum predicted tissue temperature with a set temperature value and controlling the transmission of RF heating energy based on the comparison.

7. The method of claim 1, wherein the body tissue is heart tissue.

8. A method of determining an electrode-tissue interface characterization indicator, comprising:

placing an electrode adjacent the body tissue to create an electrode-tissue interface;

transmitting RF energy to the electrode for a short duration and measuring first and second temperatures from resultant tissue-electrode interface heating of the thermal mass of the electrode; and

determining an electrode-tissue interface characterization indicator based at least in part from the first and second measured temperatures.