Transmural ablation tool and method

• US 6,652,518 B2
• Filed: 09/28/2001
• Issued: 11/25/2003
• Est. Priority Date: 09/28/2001
• Status: Expired due to Term

• Current Assignee: Ethicon Incorporated (Johnson & Johnson)
• Original Assignee: Ethicon Incorporated (Johnson & Johnson)
• Inventors: Pendekanti, Rajesh, Wellman, Parris S.
• Primary Examiner(s): PEFFLEY, MICHAEL F
• Application Number:
  US09/966,813
• Publication Number:
  US 20030069572A1
• Time in Patent Office: 788 Days
• Field of Search: 606/41, 606/42, 606/45, 606/46, 606/48, 606/51, 607/101, 607/115, 607/116, 607/122
• US Class Current: 606/41
• CPC Class Codes: A61B 18/1402 Probes for open surgery
• CPC Class Codes: A61B 18/1442 Probes having pivoting end effectors, e.g. forceps
• CPC Class Codes: A61B 18/148 having a short, rigid shaft for accessing the inner body transcutaneously, e.g. for neurosurgery or arthroscopy
• CPC Class Codes: A61B 2018/00291 using suction
• CPC Class Codes: A61B 2018/00351 Heart

Abstract

An ablation method and device contacts one surface of a target layer and positions the tissue to ablate entirely through the layer. The tissue may be a wall of the heart (ablated, for example, to form blocking lesions for atrial fibrillation), and ablation may be performed with the heart stopped or beating, and effected by either endocardial or epicardial contact. Access may be through an open incision or a minimally invasive technique involving a small opening through which one or more elongated surgical tools are inserted. Illustratively, an atrial ablation treatment can be performed prophylactically (after CABG), or independently to treat an existing condition. A tool of the present invention has a handle at a proximal end, a bipolar ablation head, and an elongated body interconnecting the handle and the ablation head. A channel or contoured surface fixes and bends the tissue such that inter-electrode conduction paths span the thickness of the layer, thus dependably creating a fully transmural ablation lesion. The oriented transmural energy conduction paths reduce the possibility of inducing coagulation of blood in the heart chamber. One bipolar assembly has an electrode spacing of approximately ten millimeters across a channel of about five millimeters depth. Preferably the ablation head forms a suction holder, connected through internal passages to a vacuum pressure of about 100-500 mmHg, and immobilizes the contacted tissue.

Claims

1. An ablation device comprising:

a handle at a proximal end;

an ablation head having a substantially planar tissue-contacting surface with a tissue-receiving cavity formed therein and having a plurality of electrodes disposed within the tissue-receiving cavity; and

an elongated body interconnecting the handle and the ablation head;

wherein the tissue-receiving cavity of the ablation head is shaped such that when the tissue-contacting surface of the ablation head is urged against a surface of a tissue layer, the tissue-receiving cavity receives tissue such that inter-electrode paths span a thickness dimension of the tissue to create a fully transmural ablation lesion.

2. The ablation device of claim 1, further comprising a suction assembly operative to grip tissue contacted to said ablation head.

3. The ablation device of claim 1, wherein the elongated body is deformable to set a shape for effectively positioning the ablation head at a desired site.

4. The ablation device of claim 1, wherein the plurality of electrodes extend along parallel paths.

5. The ablation device of claim 1, wherein the plurality of electrodes define a plurality of bipolar ablation path segments.

6. The ablation device of claim 1, wherein the plurality of electrodes are positioned and dimensioned to define oriented conduction paths positioned away from blood lying adjacent to the tissue layer.

7. The ablation device of claim 1, wherein the plurality of electrodes form a bipolar assembly with an electrode spacing of approximately ten millimeters across a channel of about five millimeters depth.

8. The ablation device of claim 1, wherein the ablation head forms a suction holder, connected through internal passages to a vacuum pressure of about 100-500 mmHg.

9. An ablation method comprising:

providing an ablation head having a substantially planar tissue-contacting surface adapted to be disposed on a target tissue layer, the tissue-contacting surface including a tissue-receiving cavity formed therein with multiple electrodes disposed within the tissue-receiving cavity;

placing the tissue-contacting surface of the ablation head into contact with a target tissue layer; and

applying force to the ablation head such that the target tissue layer is forced into the cavity;

whereby actuation of the electrodes in the ablation head is effective to ablate tissue along inter-electrode conduction paths forming a lesion extending entirely through the target tissue layer.

10. The ablation method of claim 9, further comprising the step of securing a surface of the target tissue layer to the ablation head.

11. The ablation method of claim 10, wherein the step of securing is performed by providing a suction passage in said ablation head to draw tissue thereagainst.

12. The ablation method of claim 9, wherein the target tissue layer is a myocardial wall, and actuating the multiple electrodes fully ablates a transmural lesion.

13. The ablation method of claim 9, wherein the step of placing the ablation head into contact with a target tissue layer is performed by contacting a cardiac surface.

14. The ablation method of claim 13, wherein the step of placing the ablation head into contact with a target tissue layer is performed to treat atrial fibrillation by contacting a circumferential region around a group of one or more pulmonary veins to create a conduction block.

15. The ablation method of claim 14, wherein the step of placing the ablation head into contact with a target tissue layer is performed by contacting endocardial tissue.

16. The ablation method of claim 14, wherein the step of placing the ablation head into contact with a target tissue layer is performed by contacting epicardial tissue.

17. The ablation method of claim 14, performed prophylactically after a CABG or similar surgical procedure.

18. The ablation method of claim 9, wherein the cavity has a depth about equal to said thickness dimension and defines an electrode spacing greater than approximately said thickness dimension.

19. The ablation method of claim 9, wherein the cavity has a shape selected from the group consisting of rectangular, circular, elliptical and a shallow dished concavity.

20. The ablation method of claim 9, wherein the cavity has a closed shape.

21. An ablation device comprising:

a handle at a proximal end;

an ablation head having a tissue-receiving cavity formed within a substantially planar tissue-contacting surface of the head, the cavity having a plurality of electrodes disposed therein; and

an elongated body interconnecting the handle and the ablation head;

wherein the tissue-receiving cavity is shaped such that when urged against a surface of a tissue layer the cavity has a depth about equal to the thickness dimension of the tissue and defines an electrode spacing greater than approximately said thickness dimension.

22. An ablation method comprising:

providing an ablation head having a tissue-receiving cavity formed therein with ablation electrodes disposed therein;

placing the tissue-contacting surface of the ablation head into contact with a target tissue layer; and

applying suction through the tissue-receiving cavity to draw tissue into the tissue-receiving cavity and position the tissue adjacent to the ablation electrodes;

whereby actuation of the ablation electrodes is effective to ablate tissue along inter-electrode conduction paths forming a lesion extending entirely through the tissue layer.