Method of sutureless closure for connecting blood vessels

• US 6,652,541 B1
• Filed: 09/18/2000
• Issued: 11/25/2003
• Est. Priority Date: 05/18/1999
• Status: Expired due to Fees

• Current Assignee: Aesculap AG (Lonza Group AG)
• Original Assignee: Cardica Incorporated
• Inventors: Yencho, Stephen A., Hausen, Bernard A., Hendricksen, Michael, Vargas, Jaime, Nielsen, Jamey
• Primary Examiner(s): Milano, Michael J.
• Assistant Examiner(s): Woo, Julian W.
• Application Number:
  US09/664,589
• Time in Patent Office: 1,163 Days
• Field of Search: 606/151, 606/153, 606/213, 606/215, 606/149, 606/152, 606/154, 606/155, 623/1.1, 623/1.11, 623/1.13, 623/1.31, 128/898
• US Class Current: 606/153
• CPC Class Codes: A61B 17/064 Surgical staples, i.e. penetrating the tissue
• CPC Class Codes: A61B 17/0644 penetrating the tissue, deformable to closed position
• CPC Class Codes: A61B 17/11 for performing anastomosis; Buttons for anastomosis
• CPC Class Codes: A61B 17/32053 Punch like cutting instruments, e.g. using a cylindrical or oval knife A61B17/326 takes precedence; trepans A61B17/1695; for use on the cornea A61F9/007
• CPC Class Codes: A61B 17/3415 for introducing tubes or catheters, e.g. gastrostomy tubes, drain catheters A61B17/3417 takes precedence; body piercing catheter guide needles A61M25/06
• CPC Class Codes: A61B 17/3439 with means for changing the inner diameter of the cannula, e.g. expandable A61B17/3423, A61B17/3431 take precedence; catheters A61M25/0662
• CPC Class Codes: A61B 2017/00247 Making holes in the wall of the heart, e.g. laser Myocardial revascularization
• CPC Class Codes: A61B 2017/0641 having at least three legs as part of one single body
• CPC Class Codes: A61B 2017/1107 for blood vessels
• CPC Class Codes: A61B 2017/1135 End-to-side connections, e.g. T- or Y-connections
• CPC Class Codes: A61B 2018/00392 Transmyocardial revascularisation
• CPC Class Codes: A61F 2/064 with special features to facilitate anastomotic coupling anastomosis of natural blood vessels A61B17/11

Abstract

An anastomosis device is a one piece device for connecting a graft vessel to a target vessel without the use of conventional sutures. The anastomosis device includes an expandable tube configured to have a graft vessel secured to the tube. The device has an expandable linkage positioned at one end of the device and expansion of this linkage causes a first radially extending flange to fold outward. This first flange abuts an interior wall of a target vessel and a second flange is formed which abuts an exterior wall of the target vessel trapping the target vessel between the two flanges and secures the end of the graft vessel into an opening in the wall of the target vessel. The device greatly increases the speed with which anastomosis can be performed over known suturing methods and allows anastomosis to be performed in tight spaces.

Claims

1. A method of performing anastomosis, comprising:

providing a one-piece tubular anastomosis device;

everting an end of a graft vessel about an end of the anastomosis device;

puncturing a target vessel;

inserting the anastomosis device with everted graft vessel into the puncture in the target vessel;

radially expanding the anastomosis device by advancing an expander into the anastomosis device to cause a portion of the anastomosis device to deform outward forming a first annular flange; and

forming a second annular flange on the anastomosis device to trap a wall of the target vessel between the first and second annular flanges and seal the graft vessel to the target vessel.

2. The method of claim 1, wherein the expander has an outer diameter greater than an inner diameter of the anastomosis device.

3. The method of claim 1, wherein the forming of the second flange results from motion of the expander out of the anastomosis device.

4. The method of claim 3, wherein a groove on the expander catches at least a portion of the anastomosis device to form the second flange.

5. The method of claim 1, wherein the expander is an inflatable balloon.

6. The method of claim 1, wherein the radial expansion of the anastomosis device causes a portion of the device to bend at a plurality of hinges to form the first annular flange.

7. The method of claim 1, wherein the first and second annular flanges each form an angle between about 45 and 100 degrees with an axis of the device.

8. A method of performing anastomosis, comprising

providing a one-piece tubular expandable anastomosis device;

everting the end of a graft vessel about an end of the anastomosis device;

creating an opening in a target vessel;

inserting the anastomosis device with the everted graft vessel into the opening in the target vessel; and

radially expanding the tubular anastomosis device to support tissue surrounding the opening in the target vessel by longitudinally moving an expander relative to the anastomosis device.

9. A method of forming an anastomosis, comprising:

everting one end of a graft vessel about an end of a joining device;

inserting the joining device with the everted first vessel through a wall of a second vessel, said wall having an interior wall surface and an exterior wall surface;

radially expanding the joining device inside the second vessel by advancing an expander into the anastomosis device to form a first protuberance;

seating the first protuberance against the interior wall surface of the second vessel; and

forming a second protuberance in the joining device to thereby retain the wall of the second vessel between the first and second protuberances.

10. The method of claim 9, wherein the joining device comprises a body of elements which form movable linkages including hinges, radially expanding the body causing bending of the hinges to form the first protuberance.

11. The method of claim 10, wherein radially expanding the body causes bending of the hinges to form the second protuberance.