Specimen collection device and method

• US 6,653,149 B1
• Filed: 10/16/2000
• Issued: 11/25/2003
• Est. Priority Date: 10/16/2000
• Status: Expired due to Term

• Current Assignee: Inverness Medical Switzerland GmbH (Abbott Laboratories)
• Original Assignee: Applied Biotech Inc. (Johnson & Johnson)
• Inventors: Pack, Todd Denison, Tao, Yuan, Tung, Ker-kong
• Primary Examiner(s): Warden, Jill
• Assistant Examiner(s): Cole, Monique T.
• Application Number:
  US09/688,588
• Time in Patent Office: 1,135 Days
• Field of Search: 436/174, 604/317, 604/358, 604/385.01
• US Class Current: 436/174
• CPC Class Codes: A61B 10/0038 Devices for taking faeces samples; Faecal examination devices anal receptacles A61F5/451
• CPC Class Codes: Y10T 436/25 including sample preparation

Abstract

A method and device for collection of a stool specimen. Formation of the device occurs in situ by providing a liquid absorbent polymer to water contained in a toilet bowl. The hydrated polymer forms a matrix that is capable of supported a stool specimen deposited thereon. The method and device provides a simple, economical, and less distasteful means for collecting, sampling and evaluating a stool specimen for diagnosis and/or therapy.

Claims

1. A method for forming a stool collection device comprising providing a polymer to water contained in a toilet bowl, said polymer in an amount sufficient to form in-situ a gel-like matrix capable of supporting stool deposited thereon when hydrated.

2. The method of claim 1 further comprising sampling from said supported stool.

3. The method of claim 1 wherein the polymer is selected from the group consisting of polyacrylic acid salts, copolymers of acrylic acid salts and methacrylic acid salts, saponification products of methylacrylate-vinyl acetate copolymers, saponification products of starch-ethylacrylate graft copolymers, starch-acrylic acid graft copolymers, saponification products of starch-methyl methacrylate graft copolymers, acrylate homopolymers, acrylate copolymers, alkali acrylate polymers, crosslinked polyacrylic acid salts, crosslinked copolymers of acrylic acid salts and methacrylic acid salts, crosslinked saponification products of methyl acrylate-vinyl acetate copolymers, crosslinked saponification products of starch-ethyl acrylate graft copolymers, crosslinked starch-acrylic acid salt graft copolymers, crosslinked saponification products of starch methyl methacrylate graft copolymers, crosslinked saponification products of starch acrylonitrile graft copolymers and crosslinked sodium carboxymethyl cellulose, crosslinked products of polyacrylate, crosslinked products of hydrolysates of starch-acrylonitrile graft copolymers, crosslinked products of carboxymethylcellulose, crosslinked products of polyvinyl alcohols, crosslinked products of hydrolysates of methyl (meth)acrylate-vinyl acetate copolymers, crosslinked products of cellulose-sodium acrylate graft copolymer, polyethylene oxide, polyvinyl-pyrrolidine, hydroxyethyl cellulose, hydroxypropylcellulose, polymerized α

,β

-unsaturated carboxylic acids, crosslinked acrylic acid salt polymers, saponification products of crosslinked acrylic acid ester-vinyl acetate copolymers, saponification products of crosslinked starch-acrylonitrile graft copolymers, crosslinked polyvinyl alcohols grafted with maleic anhydride, saponified polymers or copolymers or starch graft copolymers of 2-propenenitrile, 2-methyl-2-proenitrile, saponified crosslinked homopolymers of acrylonitrile or methacrylonitrile, and saponified graft copolymers of starch and polyacrylonitrile or polymethacrylonitrile, and combinations thereof.

4. The method of claim 1 wherein the liquid absorbent polymer is selected from the group consisting of an acrylic acid polymer, a starch graft copolymer of 2-propenenitrile, and combinations thereof.

5. The method of claim 1 wherein said sufficient amount of said polymer is contained in a packet.

6. The method of claim 1 wherein said polymer is provided in an amount between about 10 g to about 30 g.

7. The method of claim 1 further comprising evaluating said supported stool.

8. A method for collecting a stool sample comprising providing a hydratable polymer to water contained in a toilet bowl, said polymer in an amount sufficient to form in-situ a gel-like matrix capable of supporting stool deposited thereon when hydrated, and providing said stool sample to said matrix.

9. The method of claim 8 wherein said polymer is provided by adding a packet containing said sufficient amount of said polymer to said toilet bowl.

10. The method of claim 8 wherein said liquid absorbent polymer is selected from the group consisting of polyacrylic acid salts, copolymers of acrylic acid salts and methacrylic acid salts, saponification products of methylacrylate-vinyl acetate copolymers, saponification products of starch-ethylacrylate graft copolymers, starch-acrylic acid graft copolymers, saponification products of starch-methyl methacrylate graft copolymers, acrylate homopolymers, acrylate copolymers, alkali acrylate polymers, crosslinked polyacrylic acid salts, crosslinked copolymers of acrylic acid salts and methacrylic acid salts, crosslinked saponification products of methyl acrylate-vinyl acetate copolymers, crosslinked saponification products of starch-ethyl acrylate graft copolymers, crosslinked starch-acrylic acid salt graft copolymers, crosslinked saponification products of starch methyl methacrylate graft copolymers, crosslinked saponification products of starch acrylonitrile graft copolymers and crosslinked sodium carboxymethyl cellulose, crosslinked products of polyacrylates, crosslinked products of hydrolysates of starch-acrylonitrile graft copolymers, crosslinked products of carboxymethylcellulose, crosslinked products of polyvinyl alcohols, crosslinked products of hydrolysates of methyl (meth)acrylate-vinyl acetate copolymers, crosslinked products of cellulose-sodium acrylate graft copolymers, polyethylene oxide, polyvinyl-pyrrolidine, hydroxyethyl cellulose, hydroxypropylcellulose, polymerized α

,β

-unsaturated carboxylic acids, crosslinked acrylic acid salt polymers, saponification products of crosslinked acrylic acid ester-vinyl acetate copolymers, saponification products of crosslinked starch-acrylonitrile graft copolymers, crosslinked polyvinyl alcohols grafted with maleic anhydride, saponified polymers or copolymers or starch graft copolymers of 2-propenenitrile, 2-methyl-2-propenenitrile, saponified crosslinked homopolymers of acrylonitrile or methacrylonitrile, and saponified graft copolymers of starch and polyacrylonitrile or polymethacrylonitrile, and combinations thereof.

11. The method of claim 8 wherein said liquid absorbent polymer is selected from the group consisting of an acrylic acid polymer, a starch graft copolymer of 2-propenenitrile, and combinations thereof.

12. A stool retention device comprising a stool retaining matrix formed in situ by providing a hydratable granular acrylic acid polymer to water contained in a toilet bowl, said matrix capable of retaining stool deposited thereon.

13. A stool retention device comprising a stool retaining matrix formed in situ by providing a hydratable spherical acrylic acid polymer to water contained in a toilet bowl, said matrix capable of retaining stool deposited thereon.