Method and device for enhancing vessel occlusion

• US 6,656,173 B1
• Filed: 04/30/2001
• Issued: 12/02/2003
• Est. Priority Date: 02/22/1996
• Status: Expired due to Term

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Radio Therapeutics Corporation (Boston Scientific Corporation)
• Inventors: Palermo, Thomas
• Primary Examiner(s): Dvorak, Linda C. M.
• Assistant Examiner(s): Vrettakos, Peter J
• Application Number:
  US09/845,774
• Time in Patent Office: 946 Days
• Field of Search: 606/41-52, 606/157, 606/158
• US Class Current: 606/32
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 18/1442 Probes having pivoting end effectors, e.g. forceps
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2018/00214 Expandable means emitting energy, e.g. by elements carried thereon
• CPC Class Codes: A61B 2018/1253 monopolar

Abstract

Body lumens such as blood vessels are selectively occluded by applying radiofrequency voltage to a vaso-occlusive coil (100) at the target site (TS) and generating a thermal reaction to induce fibrogenic occlusion of the blood vessel (BV) around the vaso-occlusive coil. The radiofrequency current is usually sufficient to induce thermal damage to the luminal wall and to coagulate the surrounding blood, thereby initiating clotting and subsequent fibrosis to permanently occlude the lumen. The invention also includes a method for endoluminally deploying the vaso-occlusive coil and preventing migration of the coil from of the target site.

Claims

1. A lumen occlusion system, comprising:

a source of high frequency electrical energy;

an introducer having a shaft with proximal and distal ends and an axial lumen therebetween;

a positioner disposed within the axial lumen and having a shaft and a distal engaging element for contacting a vaso-occlusive element at a target site within a body lumen, the distal engaging element comprising a first electrode coupled to the source of high frequency electrical energy; and

a second electrode coupled to the source of high frequency electrical energy

wherein the distal engaging element has an opened and closed configuration, and the positioner is slidable relative to the introducer to close the distal engaging element when the distal engaging element is unconfined outside the axial lumen of the introducer.

2. The system of claim 1 wherein the distal engaging element comprises means for advancing the vaso-occlusive element through the axial lumen of the introducer to a target site in a body lumen.

3. The system of claim 1 wherein the distal engaging element comprises a holding member for releasably holding a portion of a vaso-occlusive element.

4. The system of claim 1 wherein the holding member is configured to releasably hold the vaso-occlusive element beyond the distal end of the introducer.

5. The system of claim 1 wherein the second electrode comprises an external dispersive electrode adapted for engaging an external portion of the patient'"'"'s body.

6. The system of claim 1 wherein the second electrode is a return electrode coupled to the introducer shaft, the return electrode being spaced from and electrically insulated from the first electrode.

7. The system of claim 1 wherein the first and second electrodes are located on the distal engaging element and the positioner shaft for initiating current therebetween.

8. The system of claim 1 wherein the introducer is a flexible shaft having dimensions suitable for introduction to a patient'"'"'s vasculature.

9. The system of claim wherein the source of radiofrequency energy is configured to apply radiofrequency energy at a frequency of at least 200 kHz to the vaso-occlusive element.

10. A lumen occlusion system, comprising:

a source of high frequency electrical energy;

an introducer having a shaft with proximal and distal ends and an axial lumen therebetween;

a positioner disposed within the axial lumen and having a shaft and a distal engaging element for contacting a vaso-occlusive element at a target site within a body lumen, the distal engaging element comprising a first electrode coupled to the source of high frequency electrical energy; and

a second electrode coupled to the source of high frequency electrical energy;

wherein the distal engaging element comprises a plurality of opposed members movable between open and closed positions, at least one of the opposed members comprising the first electrode.

11. The system of claim 10 wherein the positioner further includes a proximal actuator for opening and closing the opposed members.

12. The system of claim 10 wherein the opposed members are biased towards each other.

13. A lumen occlusion device for use with a source of high frequency electrical energy comprising:

an introducer having a shaft with proximal and distal ends and an axial lumen therebetween;

a positioner slidably disposed within the axial lumen and having a distal engaging element for releasably engaging an electrically conductive vaso-occlusive element at a target site within a body lumen, the distal engaging element comprising an electrode; and

an electrical conductor for coupling the electrode to the source of high frequency electrical energy

wherein the distal engaging element has an opened and closed configuration, and the positioner is slidable relative to the introducer to close the distal engaging element when the distal engaging element is unconfined outside the axial lumen of the introducer.

14. The device of claim 13 wherein the distal engaging element comprises means for releasably holding the vaso-occlusive element in contact with the electrode beyond the distal end of the introducer.

15. The device of claim 13 wherein the distal engaging element comprises a distal surface sized to engage the vaso-occlusive element and to push said element through the axial lumen of the introducer, the vaso-occlusive element being released from the distal surface of the engaging element when the vaso-occlusive element is pushed beyond the distal end of the introducer shaft.

16. The device of claim 13 wherein the distal engaging element comprises a plurality of opposed elements movable between open and closed positions, at least one of the opposed elements comprising the first electrode.

17. The system of claim 16 wherein the positioner further comprises a proximal actuator for opening and closing the opposed elements.

18. The system of claim 16 wherein the opposed elements are biased towards each other.

19. The device of claim 13 wherein the introducer is a flexible catheter.