Embolization device

• US 6,656,200 B2
• Filed: 04/06/2001
• Issued: 12/02/2003
• Est. Priority Date: 04/07/2000
• Status: Expired due to Term

• Current Assignee: Collagen Matrix, Inc.
• Original Assignee: Collagen Matrix, Inc.
• Inventors: Lin, Horng-Ban, Li, Shu-Tung, Yuen, Debbie
• Primary Examiner(s): Manahan, Todd E.
• Application Number:
  US09/827,635
• Publication Number:
  US 20020026234A1
• Time in Patent Office: 970 Days
• Field of Search: 606/108, 606/191, 606/195, 606/198, 606/200, 606/194, 623/11.11
• US Class Current: 606/191
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 17/1219 expandable in contact with liquids
• CPC Class Codes: A61L 2430/36 for embolization or occlusion, e.g. vaso-occlusive compositions or devices artificial blood vessels A61L27/507
• CPC Class Codes: A61L 31/044 Collagen
• CPC Class Codes: A61L 31/10 Macromolecular materials
• CPC Class Codes: A61L 31/18 Materials at least partially X-ray or laser opaque
• CPC Class Codes: C08L 5/08 Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof

Abstract

This invention relates to an embolization device for occluding a vessel. This device includes a matrix made of a biocompatible and biopolymeric material and a radiopaque material, wherein the radiopaque material is interspersed in the biocompatible and biopolymeric material. The matrix can adopt a linear extended form or a folded relaxed form.

Claims

1. An embolization device, comprising a matrix that includes a biodegradable and biocompatible biopolymeric material and a radiopaque material, wherein the radiopaque material is interspersed in the biopolymeric material, and the matrix adopts a linear extended form or a folded relaxed form.

2. The embolization device of claim 1, wherein the extended form is non-coiled.

3. The embolization device of claim 2, wherein the relaxed form is spherical, random, or cylindrically coiled.

4. The embolization device of claim 1, wherein the extended form is a coil defining a channel.

5. The embolization device of claim 4, further comprising a strand disposed in the channel, wherein the strand includes a biocompatible and biopolymeric material and adopts a linear extended form or a folded relaxed form as part of the matrix.

6. The embolization device of claim 5, wherein the relaxed form is spherical, random, or cylindrically coiled.

7. The embolization device of claim 4, wherein the relaxed form is spherical, random, or cylindrically coiled.

8. The embolization device of claim 1, further comprising a sheath surrounding the matrix, wherein the sheath includes a biocompatible and biopolymeric material and adopts a linear extended form or a folded relaxed form as the matrix.

9. The embolization device of claim 8, wherein the extended form is non-coiled.

10. The embolization device of claim 9, wherein the relaxed form is spherical, random, or cylindrically coiled.

11. The embolization device of claim 8, further comprising a strand disposed in the channel, wherein the strand includes a biocompatible and biopolymeric material and adopts a linear extended form or a folded relaxed form as part of the matrix.

12. The embolization device of claim 11, wherein the relaxed form is spherical, random, or cylindrically coiled.

13. The embolization device of claim 8, wherein the extended form is a coil defining a channel.

14. The embolization device of claim 13, wherein the relaxed form is spherical, random, or cylindrically coiled.

15. The embolization device of claim 1, wherein the biocompatible and biopolymeric material is a collagen.

16. The embolization device of claim 15, wherein the extended form is non-coiled.

17. The embolization device of claim 16, wherein the relaxed form is spherical, random, or cylindrically coiled.

18. The embolization device of claim 15, wherein the extended form is a coil defining a channel.

19. The embolization device of claim 18, further comprising a strand disposed in the channel, wherein the strand includes a biocompatible and biopolymeric material and adopts a linear extended form or a folded relaxed form as part of the matrix.

20. The embolization device of claim 19, wherein the relaxed form is spherical, random, or cylindrically coiled.

21. The embolization device of claim 18, wherein the relaxed form is spherical, random, or cylindrically coiled.

22. The embolization device of claim 15, further comprising a sheath surrounding the matrix, wherein the sheath includes a biocompatible and biopolymeric material and adopts a linear extended form or a folded relaxed form as the matrix.

23. The embolization device of claim 22, wherein the extended form is non-coiled.

24. The embolization device of claim 22, wherein the extended form is a coil defining a channel.

25. The embolization device of claim 22, further comprising a strand disposed in the channel, wherein the strand includes a biocompatible and biopolymeric material and adopts a linear extended form or a folded relaxed form as part of the matrix.