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Tray for macromolecule crystallization and method of using the same

  • US 6,656,267 B2
  • Filed: 07/10/2001
  • Issued: 12/02/2003
  • Est. Priority Date: 07/10/2001
  • Status: Expired due to Fees
First Claim
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1. A method of forming macromolecular crystals, comprising the steps of:

  • providing a macromolecule crystallization tray including a plurality of crystallization cells, each cell including a reservoir adapted to receive a equilibrating solution, a shelf located adjacent to the reservoir and adapted for use as at least one of a sample drop holding area and a temporary cryogenic holding area for a crystallized substance, and a sample drop receptacle within the shelf and adapted to receive a sample drop including a crystallizable substance;

    dispensing a equilibrating solution in the reservoirs;

    dispensing a plurality of macromolecular solution droplets in the sample drop receptacles;

    coveting the cells with a cover; and

    crystallizing the crystallizable substance by vapor diffusion.

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