Bioabsorbable bag containing bioabsorbable materials of different bioabsorption rates for tissue engineering
First Claim
1. A device for tissue engineering comprising:
- a) a porous bioabsorbable bag;
b) at least two bioabsorbable materials each material having a different rate of bioabsorption, the materials being of sufficient size so as to be contained within the porous bag; and
c) a bioabsorbable binding gel which sets and binds the bioabsorbable materials in relation to each other.
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Accused Products
Abstract
A device for tissue engineering is formed of a porous bioabsorbable bag containing at least two bioabsorbable materials having different rates of bioabsorption such as beads of different degrading rates and a bioabsorbable binding gel such as fibrin that binds the bioabsorbable materials in relation to each other. Slow degrading beads and the bag may be made of a copolymer of poly(L-lactide) and poly(glycolide), and fast degrading beads may be made of gelatin. The bag may contain cells and/or wound healing stimulants such as growth factors. Hydrolyzing enzymes may be used to enhance biodegradation of polymers. The device can be used to promote in-growth of host tissue into a void by inserting the bag with its contents into the void and conforming the bag to a desired shape. The binding gel may be injected into the bag after being placed in the void .
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Citations
14 Claims
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1. A device for tissue engineering comprising:
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a) a porous bioabsorbable bag;
b) at least two bioabsorbable materials each material having a different rate of bioabsorption, the materials being of sufficient size so as to be contained within the porous bag; and
c) a bioabsorbable binding gel which sets and binds the bioabsorbable materials in relation to each other. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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Specification