Electrochemical sensor

• US 6,660,141 B1
• Filed: 10/01/2001
• Issued: 12/09/2003
• Est. Priority Date: 11/28/1998
• Status: Expired due to Fees

• Current Assignee: Platform Diagnostics Limited
• Original Assignee: Moorlodge Ventures Limited
• Inventors: Minter, Stephen, Minter, Timothy
• Primary Examiner(s): Tung, T.
• Assistant Examiner(s): NOGUEROLA, ALEXANDER STEPHAN
• Application Number:
  US09/856,809
• Time in Patent Office: 799 Days
• Field of Search: 204/403.01, 204/403.15, 204/416, 204/409, 204/400
• US Class Current: 204/400
• CPC Class Codes: G01N 27/3275 Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
• CPC Class Codes: G01N 33/5438 Electrodes

Abstract

The present invention relates to an electrochemical sensor for a liquid sample. The sensor comprises a substrate (1) along which a liquid may travel by capillary action, said substrate being associated with an electrochemical detection arrangement (3) and a power source therefor, wherein the power source comprises at least one pair of electrodes (7, 8) of dissimilar material provided on the substrate and arranged such that liquid travel between the electrodes causes a current to be generated for operating the electrochemical detection arrangement.

Claims

1. An electrochemical sensor for a liquid sample, the sensor comprising a substrate along which a liquid sample may travel by capillary action, said substrate being associated with an electrochemical detection arrangement and a power source therefor, wherein the power source comprises at least one pair of electrodes of dissimilar material provided on the substrate and arranged such that liquid sample will travel by capillary action between the pairs of electrodes of said at least one pair of electrodes causing a current to be generated by said power source for operating the electrochemical detection arrangement.

2. An electrochemical sensor as claimed in claim 1 in which said at least one pair of electrodes separately comprise carbon, or one or more metals.

3. An electrochemical sensor as claimed in claim 1 in which said at least one pair of electrodes separately comprises copper and zinc.

4. An electrochemical sensor according to claim 1 in which one or more of said at least one pair of dissimilar materials are interdigitated such that current, in the presence of liquid, may flow from one electrode to the other electrode of the electrode pair.

5. An electrochemical sensor according to claim 1 comprising a first liquid travel track provided over at least part of the length of said substrate upon which said power source is formed comprising interdigitated electrodes of dissimilar materials, and a second liquid travel track also provided over at least part of the length of said substrate, the downstream end of the second track being provided with a detection electrode arrangement associated with the electrochemical detection arrangement.

6. An electrochemical sensor according to claim 5 in which said first and second liquid travel tracks are separated by a liquid impermeable barrier.

7. An electrochemical sensor according to claim 1 further comprising indicator means.

8. An electrochemical sensor according to claim 7 in which the indicator means comprises a liquid crystal display.

9. An electrochemical sensor according to claim 1, in which the substrate comprises one or more reagents which in the presence of the species under test induce a reaction that produces a species that is directly or indirectly electrochemically detectable at the electrochemical detection arrangement.