2-acylaminobenzimidazole derivatives for treating glaucoma
First Claim
Patent Images
1. A compound of the formula:
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wherein;
X=H, F, Cl, Br, OR1, CN, C(═
O)R1, C(═
O)NR1R2, C1-6 alkyl, OC(═
O)R1, OC(═
O)NR1R2, or CF3;
R, R1, R2=H or C1-6alkyl;
Y=CH2NRR2 or CHR1NRR2 or with the proviso that when X=H, Y does not equal CH2N(CH2CH3)2;
Z=CH;
R3=H, F, Cl, Br, OR1, CN, C1-6 alkyl or CF3; and
R4=H, C1-3 alkyl, F, Cl, Br, I or CF3.
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Abstract
2-Acylaminobenzimidazole deviates useful for treating glaucoma are disclosed.
41 Citations
2 Claims
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1. A compound of the formula:
-
wherein; X=H, F, Cl, Br, OR1, CN, C(═
O)R1, C(═
O)NR1R2, C1-6 alkyl, OC(═
O)R1, OC(═
O)NR1R2, or CF3;
R, R1, R2=H or C1-6alkyl;
Y=CH2NRR2 or CHR1NRR2 or with the proviso that when X=H, Y does not equal CH2N(CH2CH3)2;
Z=CH;
R3=H, F, Cl, Br, OR1, CN, C1-6 alkyl or CF3; and
R4=H, C1-3 alkyl, F, Cl, Br, I or CF3. - View Dependent Claims (2)
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Specification
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Current AssigneeNovartis Ag
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Original AssigneeAlcon Incorporated
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InventorsAbdelmoula, Namil, Ruskinko, Andrew, Hellberg, Mark R.
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Primary Examiner(s)Morris, Patricia L.
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Application NumberUS10/221,251Time in Patent Office455 DaysField of Search548/307.4US Class Current548/307.4CPC Class CodesA61P 27/06 Antiglaucoma agents or mioticsC07D 235/30 Nitrogen atoms not forming ...
