Ultrasonic method and device for wound treatment

• US 6,663,554 B2
• Filed: 08/07/2002
• Issued: 12/16/2003
• Est. Priority Date: 04/23/2001
• Status: Expired due to Term

• Current Assignee: SANUWAVE Health, Inc.
• Original Assignee: Celleration, Inc. (Adynxx, Inc)
• Inventors: Babaev, Eilaz
• Primary Examiner(s): Lateef, Marvin M.
• Assistant Examiner(s): QADERI, RUNA S
• Application Number:
  US10/214,339
• Publication Number:
  US 20020190136A1
• Time in Patent Office: 496 Days
• Field of Search: 601/2, 601/3, 604/22, 604/24, 604/68-73, 604/890.1, 600/437, 600/439, 606/1
• US Class Current: 600/2
• CPC Class Codes: A61M 11/005 using ultrasonics spraying or atomising liquids using ultrasonic vibrations in general B05B17/06
• CPC Class Codes: A61M 2205/058 with ultrasound therapy
• CPC Class Codes: A61M 35/30 Gas therapy for therapeutic treatment of the skin
• CPC Class Codes: A61N 7/00 Ultrasound therapy lithotripsy A61B17/22, A61B17/225; massage using supersonic vibration A61H23/00 ; using ultrasound for introducing media into the body A61M37/0092
• CPC Class Codes: B05B 17/0623 coupled with a vibrating horn
• CPC Class Codes: B05B 17/063 having an internal channel for supplying the liquid or other fluent material

Abstract

The method and device of the present invention for ultrasound wound treatment includes a transducer to produce ultrasonic waves. The ultrasonic transducer has tip with the distal end (radiation surface). A liquid is directed to the radiation surface throug central orifice or separate tube wherein an directed atomized particle spray of the liquid is created upon contact of the liquid with the radiation surface. The spray directed to the wound from at least 0.1 inches transmits ultrasound waves trough particles and has an irrigation, mechanical cleansing, liquid energizing and bactericide effect.

Claims

1. A method for treating a wound comprising the steps of:

providing a transducer having a distal radiation surface arranged a distance from the surface of the wound for emitting ultrasonic energy and defining at least two orifices therethrough;

introducing a liquid to the distal radiation surface via a first of the at least two orifices;

introducing a gas to the distal radiation surface via a second of the at least two orifices, wherein the liquid and gas form a gas-liquid spray; and

delivering the emitted ultrasonic energy to the wound through the gas-liquid spray, wherein the ultrasonic energy penetrates the wound tissue to a beneficial depth to provide a bactericidal and a therapeutic effect for decreasing the healing time for the wound.

2. The method according to claim 1, wherein the transducer operates at a frequency from 18 kHz to 10,000 MHz.

3. The method according to claim 1, wherein the transducer operates at a frequency from 35 kHz to 45 kHz.

4. The method according to claim 1, wherein the distal radiation surface is positioned from 0.1 to 20 inches from the surface of the wound.

5. The method according to claim 1, wherein the liquid includes one or more components selected from the group consisting of antibiotics, antiseptics, saline solutions, oils, and water.

6. The method according to claim 1, wherein the delivering step includes the step of delivering the emitted ultrasonic energy for a predetermined time for achieving the bactericidal and therapeutic effects, and further comprising the step of repeating the treatment method until the wound is healed.

7. The method according to claim 1, wherein the transducer is driven by at least one of a constant, pulsed, and modulated frequency, and wherein the driving wave form of the transducer is selected from the group consisting of sinusoidal, rectangular, trapezoidal and triangular wave forms.

8. The method according to claim 1, wherein the therapeutic effect is selected from the group consisting of increasing blood flow to the wound, mechanically cleansing the wound, stimulating cell growth, providing at least one medicament to the wound, and penetrating at least one medicament through the surface of the wound.

9. The method according to claim 1, wherein the first and second of the at least two orifices are coaxial with respect to each other.

10. The method according to claim 9, comprising the step of facilitating the creation of ultrasonic standing waves by providing a different length for the first of the at least two orifices than the length of the second of the at least two orifices.

11. The method according to claim 1, wherein the length of the first and second of the at least two orifices is the same.

12. The method according to claim 1, wherein the distal radiation surface has a shape selected from the group consisting of rectangular, elliptical, oval, spherical, conical, curved, stepped, and with chamfer.

13. An ultrasonic treatment system comprising:

a transducer having a distal radiation surface and defining an orifice therethrough; and

a fluid source in fluid communication with the orifice; and

an ultrasound generator for activating the transducer for generating ultrasonic energy therefrom, wherein, during treatment of a wound, fluid introduced to the distal radiation surface via the orifice is formed into a spray, wherein the fluid includes one of a liquid and a gas, wherein the generated ultrasonic energy is delivered to the wound through the spray, and wherein the ultrasonic energy penetrates the wound tissue to a beneficial depth to provide a bactericidal and a therapeutic effect for decreasing the healing time for the wound.

14. The apparatus according to claim 13, wherein the transducer operates at a frequency from 18 kHz to 10,000 MHz.

15. The apparatus according to claim 13, wherein the transducer operates at a frequency from 35 kHz to 45 kHz.

16. The apparatus according to claim 13, wherein the distal radiation surface is positioned from 0.1 to 20 inches from the surface of the wound.

17. The apparatus according to claim 13, wherein the fluid includes one or more components selected from the group consisting of gas, antibiotics, antiseptics, saline solutions, oils, and water.

18. The apparatus according to claim 13, wherein the therapeutic effect is selected from the group consisting of increasing blood flow to the wound, mechanically cleansing the wound, stimulating cell growth, providing at least one medicament to the wound, and penetrating at least one medicament through the surface of the wound.

19. The apparatus according to claim 13, wherein the transducer includes at least one more orifice, and further comprising a second fluid source in fluid communication with the at least one more orifice for introducing one of a liquid and a gas to the distal radiation surface via one orifice of the at least one more orifice.

20. The apparatus according to claim 13, wherein the distal radiation surface has a shape selected from the group consisting of rectangular, elliptical, oval, spherical, conical, curved, stepped, and with chamfer.

21. A method for treating a wound comprising the steps of:

generating ultrasonic energy at a distance from the surface of the wound, such that the generated ultrasonic energy propagates through a gaseous medium;

introducing a fluid in at least one propagation path of the generated ultrasonic energy to produce a spray, wherein the fluid includes a liquid and a gas which are introduced via at least one orifice aligned with the at least one propagation path; and

delivering the generated ultrasonic energy to the wound through the spray, wherein the ultrasonic energy penetrates the wound tissue to a beneficial depth to provide a bactericidal and a therapeutic effect for decreasing the healing time for the wound.

22. The method according to claim 21, wherein the at least one orifice includes at least one of a groove and a ring.