Methods for inhibition and dissolution of amyloidoses by administration of compositions comprising 2,4-dinitrophenol
First Claim
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1. A method for promoting the dissolution of existing amyloidoses, the method comprising administration of composition comprising a 2,4-dinitrophenol, or a pharmaceutically acceptable salt thereof, to a patient having amyloidoses in an amount sufficient to inhibit the growth of the amyloidoses or to promote the dissolution of existing amyloidoses.
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Abstract
The inhibition of the formation and development of amyloidoses, as well as the dissolution of amyloidoses in organisms is claimed. Methods for the diagnosis of amyloidoses using aromatic and heteroaromatic compounds having at least one electron-withdrawing groups are claimed.
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Citations
12 Claims
- 1. A method for promoting the dissolution of existing amyloidoses, the method comprising administration of composition comprising a 2,4-dinitrophenol, or a pharmaceutically acceptable salt thereof, to a patient having amyloidoses in an amount sufficient to inhibit the growth of the amyloidoses or to promote the dissolution of existing amyloidoses.
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2. A method for inhibiting the formation of amyloidoses, the method comprising
(a) providing a composition comprising a 2,4-dinitrophenol; - and
(b) administering the composition to an individual having amyloidoses in an amount sufficient to inhibit the formation of amyloidoses. - View Dependent Claims (10, 11, 12)
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3. A method for inhibiting the formation of an amyloid plaque, the method comprising
(a) providing a composition comprising a 2,4-dinitrophenol; - and
(b) contacting the composition with an amyloid plaque, thereby inhibiting the formation of an amyloid plaque.
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4. A method for inhibiting the growth of amyloidoses, the method comprising administration of composition comprising a 2,4-dinitrophenol, or a pharmaceutically acceptable salt thereof, to a patient having amyloidoses in an amount sufficient to inhibit the growth of the amyloidoses or to promote the dissolution of existing amyloidoses.
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5. A method for inhibiting the growth of an amyloid plaque, the method comprising
(a) providing a composition comprising a 2,4-dinitrophenol; - and
(b) contacting the composition with an amyloid plaque, thereby inhibiting the growth of an amyloid plaque or promoting the dissolution of an amyloid plaque.
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6. A method for promoting the dissolution of an amyloid plaque, the method comprising
(a) providing a composition comprising a 2,4-dinitrophenol; - and
(b) contacting the composition with an amyloid plaque, thereby inhibiting the growth of an amyloid plaque or promoting the dissolution of an amyloid plaque.
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Specification