Method and apparatus for differential phase optical coherence tomography

• US 6,665,456 B2
• Filed: 01/11/2002
• Issued: 12/16/2003
• Est. Priority Date: 01/12/2001
• Status: Expired due to Term

• Current Assignee: Board of Regents of the University of Texas System (University of Texas System)
• Original Assignee: Board of Regents of the University of Texas System (University of Texas System)
• Inventors: Telenkov, Sergey, Dave, Digant P., Milner, Thomas E.
• Primary Examiner(s): Lee, John D.
• Application Number:
  US10/044,421
• Publication Number:
  US 20030020920A1
• Time in Patent Office: 704 Days
• Field of Search: 385/1-3, 385/11, 385/12, 385/15, 356/450, 356/477-479, 356/491, 356/364, 356/369
• US Class Current: 385/11
• CPC Class Codes: A61B 5/0066 Optical coherence imaging
• CPC Class Codes: A61B 5/0261 using optical means, e.g. infrared light
• CPC Class Codes: G01B 2290/45 Multiple detectors for detecting interferometer signals
• CPC Class Codes: G01B 2290/70 Using polarization in the interferometer
• CPC Class Codes: G01B 9/0201 using temporal phase variation
• CPC Class Codes: G01B 9/02027 Two or more interferometric channels or interferometers
• CPC Class Codes: G01B 9/02028 Two or more reference or object arms in one interferometer
• CPC Class Codes: G01B 9/02045 using the Doppler effect
• CPC Class Codes: G01B 9/02091 Tomographic interferometers, e.g. based on optical coherence
• CPC Class Codes: G01N 21/4795 spatially resolved investigating of object in scattering medium in vivo A61B
• CPC Class Codes: G01P 5/001 Full-field flow measurement, e.g. determining flow velocity and direction in a whole region at the same time, flow visualisation
• CPC Class Codes: G01P 5/26 by measuring the direct influence of the streaming fluid on the properties of a detecting optical wave

Abstract

One form of the present invention is a dual channel optical reflectometer composed of a birefringent path coupler and an optical source path that is optically connected to the path coupler. After entering the path coupler, light is split into birefringent reference and sample paths. The reference path is optically aligned with a first collimating lens, and the collimating lens is directed into a scanning delay line. There is also a birefringent optical sample path that is also optically connected to the path coupler. The sample path is optically aligned with a polarization channel separator/combiner and a lens, to focus and direct optical beams into the turbid sample. Light backscattered from the turbid sample is collected by the second lens and orthogonal polarization channels are reunited by the polarization channel combiner. An analog-to-digital converter is connected to the amplifier, and a computer is connected to the analog-to-digital converter to analyze the output.

Claims

1. A dual channel optical reflectometer comprising:

a broad bandwidth optical light source;

an optical source path incorporating a depolarizing element that decorrelates optical signals in orthogonal fiber polarization channels and optically connects both channels to a path coupler;

a path coupler that separates light into birefringent sample and reference paths while maintaining energy separation and decorrelation of optical signals in the fast and slow fiber polarization channels;

a birefringent optical reference path optically connected to the path coupler and optically coupled to a scanning delay line;

a birefringent optical sample path optically connected to the path coupler, wherein the birefringent sample path comprises a polarization channel separator/combiner, wherein the polarization separator-combiner divides/reunites optical signals in fast and slow polarization channels into two distinct optical beams that intersect at a single point in the sample under test, wherein the polarization channel separator is optically connected to a beam combiner that reunites optical signals in fast and slow polarization channels;

the birefringent reference and sample paths are configured so that optical path length differences between fiber reference and sample paths in the fast and slow channels are less than one-half wavelength of incident light;

a birefringent optical detection path optically connected to the path coupler and a polarization channel separator that is optically coupled to a first and second photoreceivers that produce first and second output signals, respectively, wherein the first and second output signals pass through a bandpass filter and amplifier;

an analog-to-digital converter connected to the bandpass filter-amplifier; and

a computer connected to the analog-to-digital converter.

2. The dual channel reflectometer as recited in claim 1, where the light source is an optical semiconductor amplifier.

3. The dual channel reflectometer as recited in claim 1, where the light source is an optical semiconductor amplifier centered at 1.3 microns and with a FWHM of about 60 nm.

4. The dual channel reflectometer as recited in claim 1, wherein the path coupler is a 2×

2 phase-maintaining coupler.

5. The dual channel optical reflectometer as recited in claim 1, wherein the analog-digital converter is a 12-bit converter.

6. The dual channel optical reflectometer as recited in claim 1, wherein the source path further comprises a depolarizer.

7. The dual channel optical reflectometer as recited in claim 6, wherein the depolarizer is a Lyot depolarizer.

8. A dual channel optical reflectometer comprising:

a path coupler that separates light into birefringent sample and reference paths while maintaining energy separation and decorrelation of optical signals in orthogonal fiber polarization channels;

a source path comprising a first birefringent optical fiber having a first end and a second end;

the first end of the first optical fiber optically coupled to a light source and splitting the light source into a first and second polarization channels with independent phase components;

the second end of the first optical fiber connected to a depolarizer;

a second birefringent optical fiber having a first end and a second end, and the first end of the second optical fiber connected to the depolarizer; and

the second end of the second optical fiber optically connected to the path coupler;

a reference path comprising a third birefringent optical fiber having a first end and a second end;

the first end of the third optical fiber optically connected to the path coupler;

the second end of the third optical fiber optically aligned with a first collimating lens that collimates, wherein the first collimating lens collimates light emitting from the second end of the third optical fiber into a rapid scanning delay line that includes a galvanometer that allows a variable phase modulation frequency;

a sample path comprising a fourth birefringent optical fiber having a first and a second end;

the first end of the fourth optical fiber optically connected to the path coupler;

the second end of the fourth optical fiber optically aligned with a second collimating lens, wherein the second collimating lens collimates light emitting from the second end of the fourth optical fiber through a first Wollaston prism and a focusing lens, wherein the focusing lens is aligned so that the light with two decorrelated polarization channels with independent phase components are focused at a single point on a sample;

a detection path comprising a fifth birefringent optical fiber having a first end and a second end;

the first end of the fifth optical fiber optically connected to the path coupler;

the second end of the fifth optical fiber optically aligned with a third collimating lens, wherein the third collimating lens collimates the light emitting from the fifth optical fiber onto a second Wollaston prism, wherein the second Wollaston prism splits the light from the fifth optical fiber into a first beam and a second beam, each beam corresponding to one phase component;

a first photodetector detects the first beam and produces a first output signal;

a second photodetector detects the second beam and produces a second output signal;

the first and second output signals pass through a bandpass filter and amplifier to produce a first and a second filtered signal;

an analog-to-digital converter is connected to the bandpass filter-amplifier; and

a processor is connected to the analog-to-digital converter.

9. The dual channel optical low-coherence reflectometer as recited in claim 8, wherein the depolarizer is a decorrelator comprising a birefringent crystal or a segment of a birefringent fiber, selectively, with fast and slow axes aligned to the orthogonal polarization channels of the reflectometer.

10. The dual channel reflectometer as recited in claim 8, wherein the galvanometer has a scan rate of 180 Hz and the phase modulation frequency is 30 kHz.

11. The dual channel reflectometer as recited in claim 8, wherein the light source is a broadband light source.

12. The dual channel reflectometer as recited in claim 8, where the light source is an optical semiconductor amplifier.

13. The dual channel reflectometer as recited in claim 8, where the light source is an optical semiconductor amplifier centered at 1.3 microns and with a FWHM of about 60 nm.

14. The dual channel reflectometer as recited in claim 8, wherein the path coupler is a 2×

2 polarization-maintaining coupler.

15. The dual channel reflectometer as recited in claim 8, wherein galvanometer has a scan rate of 180 Hz and the phase modulation frequency is 30 kHz.

16. The dual channel optical reflectometer as recited in claim 8, wherein the analog-digital converter is a 12-bit converter.

17. The dual channel optical reflectometer as recited in claim 8, wherein the analysis of the output comprises calculation of the Doppler frequency shift.

18. The dual channel optical reflectometer as recited in claim 8, wherein the sample comprises a highly light-scattering media.

19. The dual channel optical reflectometer as recited in claim 8, wherein the sample is in vivo blood flow.

20. The dual channel optical reflectometer as recited in claim 8, wherein the second birefringent optical fiber is at least two meters in length.

21. A birefringent optical fiber sample path optically aligned with an optical component disposed to inject decorrelated light into the optical fiber sample path comprising two decorrelated light signals in orthogonal polarization channels, the sample path being further optically aligned with a collimating lens, a Wollaston prism and a focusing lens, wherein the focusing lens is disposed to focus optical beams of decorrelated light corresponding to the decorrelated polarization channels to a single point in a sample.

22. The birefringent optical fiber sample path as recited in claim 21, wherein the sample comprises a highly light-scattering media.

23. The birefringent optical fiber sample path as recited in claim 21, wherein the sample is in vivo blood flow.

24. A method for measuring a Doppler-angle between light propagation and flow velocity vectors and comprising the steps of:

creating an optical source path;

creating an optical reference path that is optically coupled to a first collimating lens, wherein the collimating lens is directed into a rapid scanning delay line;

creating an optical sample path that is optically coupled to a second collimating lens, a first Wollaston prism, and a focusing lens, wherein the focusing lens focuses to a single point on a sample;

creating a birefringent optical detection path optically coupled to a third collimating lens and a second Wollaston prism, wherein the second Wollaston prism is optically coupled to first and second photoreceivers that produce first and second output signals, respectively, wherein the first and second output signals pass through a bandpass filter and amplifier to produce first and second filtered signals;

connecting the source path, the reference path, the sample path and the detection path to a path coupler;

converting the first and second filtered signals with an analog-digital converter; and

connecting a computer to the analog-digital converter for data analysis.

25. A birefringent optical fiber sample path optically aligned with an optical component disposed to inject decorrelated light into the optical fiber sample path comprising two decorrelated light signals in orthogonal polarization channels, the sample path being further optically aligned with a collimating lens, a Wollaston prism that produces two beams of decorrelated light, and a focusing lens, wherein the two beams of decorrelated light are collinear and longitudinally displaced relative to each other.

26. The birefringent optical fiber sample path recited in claim 25, wherein the longitudinal displacement of the two beams relative to one another is time dependant.

27. A birefringent optical fiber sample path optically aligned with an optical component disposed to inject decorrelated light into the optical fiber sample path comprising two decorrelated light signals in orthogonal polarization channels, the sample path being further optically aligned with a collimating lens, a Wollaston prism that produces two beams of decorrelated light, and a focusing lens, wherein the two beams of decorrelated light are horizontally separated relative to one another, and the horizontal separation is time dependent.

28. A birefringent optical fiber reference path optically aligned with an optical component disposed to inject decorrelated light into the optical fiber reference path comprising two decorrelated light signals in orthogonal polarization channels, the optical fiber reference path having an output spliced at 45°

to an input of a birefringent fiber of a phase modulator, so that light of both channels of said reference path is equally coupled into the slow axis of said phase modulator input birefringent fiber.

29. The birefringent optical fiber reference path as recited in claim 28, wherein the phase modulator comprises a lithium niobate Y-waveguide electro-optic phase modulator.

30. The birefringent optical fiber reference path as recited in claim 28, wherein said phase modulator has two phase modulator arms that are respectively driven with different frequencies to generate frequency multiplexed optical signals, and a detector path associated with the birefringent optical fiber reference path is provided with a digital filter for separating the frequency multiplexed signals.