Device and method for perfusing peritoneal dialyzing fluid

• US 6,666,842 B1
• Filed: 04/04/2001
• Issued: 12/23/2003
• Est. Priority Date: 10/07/1998
• Status: Expired due to Fees

• Current Assignee: Asahi Sakai
• Original Assignee: Asahi Sakai
• Inventors: Sakai, Asahi
• Primary Examiner(s): Casler, Brian L.
• Assistant Examiner(s): Han, Mark K
• Application Number:
  US09/806,686
• Time in Patent Office: 993 Days
• Field of Search: 604/29, 604/4.01, 604/5.01, 604/5.04, 604/6.09, 604/6.11, 604/6.13, 604/93.01, 604/113, 604/131, 604/151, 604/264, 604/272, 604/523, 210/644, 210/645, 210/646, 210/649, 210/650, 210/651, 210/767, 210/175, 210/181, 210/194, 210/195.2, 210/348, 210/439, 210/500.1
• US Class Current: 604/29
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/284 Continuous flow peritoneal dialysis [CFPD]

Abstract

An instrument for continuous recirculation of peritoneal dialysate to infuse and drain out the dialysate automatically through catheters implanted in a peritoneal cavity of a human body. The instrument includes a prefilter, a primary filter comprising a semipermeable membrane having a maximum permeable molecule of up to 30,000 dalton, a pump for lowering the outside pressure of the primary filter relative to the inside pressure, a secondary filter having a semipermeable membrane having a maximum permeable molecule of 5,000 dalton, a pump for raising the pressure of a supplemental liquor line relative to the inside of a secondary filter line, and a method of recirculating dialysate using the above-mentioned instrument. The recirculation instrument permits the reuse of protein which is permeated out from a patient'"'"'s body, as an osmotic agent in peritoneal dialysate, in order to maintain a disinfected recirculating line, and to improve an ultrafiltration rate and clearance of uremic toxin.

Claims

1. An instrument for continuous recirculation of peritoneal dialysate to infuse and drain out the dialysate automatically through catheters implanted in a peritoneal cavity of a human body, said instrument comprising:

a prefilter;

a primary filter located downstream of said prefilter, said primary filter being operable to filter out a portion of the dialysate, and said primary filter comprising a semipermeable membrane having a maximum permeable molecule of up to 30,000 dalton;

a suction pump operable to lower an outside pressure of said primary filter relative to an inside pressure of said primary filter;

a feeding pump operable to supply a fresh dialysate; and

a secondary filter located downstream of said feeding pump, said secondary filter being operable to filter out a portion of the fresh dialysate, and said secondary filter comprising a semipermeable membrane having a maximum permeable molecule of up to 5,000 dalton.

2. The instrument for continuous recirculation of peritoneal dialysate according to claim 1, wherein a supplemental liquor line provides communication between said feeding pump and said secondary filter.

3. The instrument for continuous recirculation of peritoneal dialysate according to claim 2, wherein said feeding pump supplies the fresh dialysate to said secondary filter through the supplemental liquor line, said feeding pump being further operable to raise the pressure of the supplemental liquor line relative to an inside pressure of said secondary filter.

4. The instrument for continuous recirculation of peritoneal dialysate according to claim 1, wherein the instrument is equipped with a dialysate recirculation line that is replaceable, made of flexible material, prefabricated as a continuous line from an outflow terminal to an inflow terminal, and sterilized.

5. The instrument for continuous recirculation of peritoneal dialysate according to claim 4, further comprising an outflow joint and an inflow joint which can be directly connectable to each other, and in an isolated case the outflow and inflow joints can be fixed adjacent to each other so that terminals of a recirculation instrument side and terminals of a patient peritoneal cavity side may be disconnected and connected by remote handling free from human contact.

6. The instrument for continuous recirculation of peritoneal dialysate according to claim 1, further comprising an outflow joint and an inflow joint which can be directly connectable to each other, and in an isolated case the outflow and inflow joints can be fixed adjacent to each other so that terminals of a recirculation instrument side and terminals of a patient peritoneal cavity side may be disconnected and connected by remote handling free from human contact.

7. The instrument for continuous recirculation of peritoneal dialysate according to claim 1, wherein said prefilter, which is located upstream of said primary filter, is operable to prevent said primary filter from becoming plugged by cells and fibrin in the dialysate withdrawn from the peritoneal cavity.