Bone hemi-lumbar interbody spinal implant having an asymmetrical leading end and method of installation thereof

• US 6,666,890 B2
• Filed: 08/28/2001
• Issued: 12/23/2003
• Est. Priority Date: 04/19/2000
• Status: Active Grant

• Current Assignee: Warsaw Orthopedic Incorporated (Medtronic Plc)
• Original Assignee: Gary K. Michelson
• Inventors: Michelson, Gary K.
• Primary Examiner(s): Robert, Eduardo C.
• Application Number:
  US09/941,425
• Publication Number:
  US 20020052655A1
• Time in Patent Office: 847 Days
• Field of Search: 623/17.11, 623/17.12, 623/17.16
• US Class Current: 623/17.11
• CPC Class Codes: A61F 2/28 Bones joints A61F2/30
• CPC Class Codes: A61F 2/442 Intervertebral or spinal discs, e.g. resilient non-disc-shaped intervertebral inflatable pockets A61F2/441; non-disc-shaped intervertebral fusion implants A61F2/4455
• CPC Class Codes: A61F 2/4455 for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages intervertebral discs A61F2/442
• CPC Class Codes: A61F 2/446 having a circular or elliptical cross-section substantially parallel to the axis of the spine, e.g. cylinders or frustocones
• CPC Class Codes: A61F 2002/2817 Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
• CPC Class Codes: A61F 2002/30062 (bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
• CPC Class Codes: A61F 2002/30593 hollow
• CPC Class Codes: A61F 2002/30777 Oblong apertures
• CPC Class Codes: A61F 2002/30785 parallel
• CPC Class Codes: A61F 2002/30904 serrated profile, i.e. saw-toothed
• CPC Class Codes: A61F 2002/448 comprising multiple adjacent spinal implants within the same intervertebral space or within the same vertebra, e.g. comprising two adjacent spinal implants
• CPC Class Codes: A61F 2210/0004 bioabsorbable
• CPC Class Codes: A61F 2310/00023 Titanium or titanium-based alloys, e.g. Ti-Ni alloys
• CPC Class Codes: A61F 2310/00029 Cobalt-based alloys, e.g. Co-Cr alloys or Vitallium
• CPC Class Codes: A61F 2310/00131 Tantalum or Ta-based alloys
• CPC Class Codes: A61F 2310/00179 Ceramics or ceramic-like structures
• CPC Class Codes: A61F 2310/00359 Bone or bony tissue
• CPC Class Codes: C10G 1/002 in combination with oil conversion- or refining processes
• CPC Class Codes: C10G 1/083 in the presence of a solvent
• CPC Class Codes: C10G 47/00 Cracking of hydrocarbon oils, in the presence of hydrogen or hydrogen- generating compounds, to obtain lower boiling fractions C10G15/00 takes precedence; destructive hydrogenation of non-melting solid carbonaceous or similar materials C10G1/06
• CPC Class Codes: C10G 47/04 : Oxides
• CPC Class Codes: C10G 47/12 : Inorganic carriers
• CPC Class Codes: C10G 65/10 : including only cracking steps

Abstract

An interbody spinal implant is formed of cortical bone adapted for placement across an intervertebral space formed across the height of a disc space between two adjacent vertebral bodies. An asymmetrical leading end on the implant is adapted to sit upon the peripheral areas, such as the apophyseal rim and the apophyseal rim area, of the vertebral end plate region of the vertebral bodies without protruding therefrom. The asymmetrical leading end allows for the safe use of an implant of maximum length for the implantation space into which it is installed. The implant can also include an asymmetric trailing end adapted to sit upon the more peripheral areas of the vertebral end plate region of the vertebral bodies.

Claims

1. An interbody spinal implant for insertion at least in part across a disc space between adjacent vertebral bodies of a human spine, the vertebral bodies having an anterior aspect and a posterior aspect, said implant comprising:

a leading end for insertion first into the disc space, a trailing end opposite said leading end, and therebetween a length along a mid-longitudinal axis of said implant, said leading end being asymmetrical;

opposed portions between said leading and trailing ends adapted to be placed within the disc space to contact and support the adjacent vertebral bodies, said opposed portions being non-arcuate along at least a portion of the length of said implant, said implant being formed of bone;

an interior facing side wall, an exterior facing side wall opposite said interior side wall, and a width therebetween, said width of said implant being less than approximately one-half of the maximum width of the adjacent vertebral bodies into which said implant is adapted to be inserted, said interior and exterior side walls connecting said opposed portions and said leading and trailing ends, said interior side wall adapted to be oriented toward another implant when inserted within the disc space;

at least one artificial through-hole between said interior facing and said exterior facing side walls passing completely through said implant from opposed portion to opposed portion and adapted to hold bone growth promoting material for permitting for the growth of bone from vertebral body to vertebral body through said implant;

a first distance as measured from said leading end to a plane perpendicular to and bisecting the length along the mid-longitudinal axis of said implant that is greater than a second distance as measured from said perpendicular plane to the junction of said leading end and said exterior side wall; and

a third distance as measured from the junction of said leading end and said interior side wall to a plane perpendicular to and bisecting the length along the mid-longitudinal axis of said implant that is greater than said second distance.

2. The implant of claim 1, wherein said first distance is greater than said third distance.

3. The implant of claim 1, wherein said first distance is less than said third distance.

4. The implant of claim 1, wherein said first distance and said third distance are approximately equal.

5. The implant of claim 1, wherein said third distance is substantially greater than said first distance.

6. The implant of claim 1, wherein said leading end is at least in part non-linear.

7. The implant of claim 1, wherein more than half of said leading end is a contour that goes from the exterior side wall toward the mid-longitudinal axis of said implant in a plane dividing said implant into an upper half and a lower half.

8. The implant of claim 1, wherein said leading end includes a curve that extends from said exterior side wall beyond the mid-longitudinal axis of said implant.

9. The implant of claim 1, wherein less than half of said leading end is along a line perpendicular to the mid-longitudinal axis of said implant in a plane dividing said implant into an upper half and a lower half.

10. The implant of claim 1, wherein at least a portion of said leading end is tapered for facilitating insertion of the implant between the two adjacent vertebral bodies.

11. The spinal implant of claim 1, wherein said implant is adapted for insertion from the posterior aspect of the vertebral bodies and said leading end is configured to conform to the anatomic contour of at least a portion of the anterior aspect of the vertebral bodies.

12. The implant of claim 1, wherein said implant is adapted for insertion from the anterior aspect of the vertebral bodies and said leading end is configured to conform to the anatomic contour of at least a portion of the posterior aspect of the vertebral bodies.

13. The implant of claim 1, wherein said implant is adapted for insertion from a first lateral aspect of the vertebral bodies and said leading end is configured to conform to the anatomic contour of at least a portion of a second lateral aspect of the vertebral bodies opposite the first lateral aspect.

14. The implant of claim 1, further comprising at least one protrusion extending from at least one of said opposed portions for engaging at least one of the adjacent vertebral bodies to maintain said implant within the disc space.

15. The implant of claim 14, wherein said protrusion comprises a ridge.

16. The implant of claim 1, further comprising a plurality of surface roughenings for engaging the adjacent vertebral bodies and for maintaining said implant in place, said surface roughenings being present on at least a portion of said opposed portions.

17. The implant of claim 1, wherein said opposed portions have a porous surface.

18. The implant of claim 1, wherein said opposed portions have a bone ingrowth surface.

19. The implant of claim 1, wherein said implant material is selected from the group including cortical fibers, bone filaments, and bone particles.

20. The implant of claim 1, in combination with a fusion promoting material other than bone.

21. The implant of claim 1, wherein said implant comprises a bone ingrowth material other than bone.

22. The implant of claim 1, further comprising a material, other than the bone from which said implant is formed, that intrinsically participates in the growth of bone from one of the adjacent vertebral bodies to the other of the adjacent vertebral bodies.

23. The implant of claim 1, wherein said implant is treated with a fusion promoting substance.

24. The implant of claim 23, wherein said fusion promoting substance is bone morphogenetic protein.

25. The implant of claim 1, wherein at least a portion of said implant is bioresorbable.

26. The implant of claim 1, further in combination with bone morphogenetic protein.

27. The implant of claim 1, further in combination with an osteogenic material.

28. The implant of claim 27, wherein said osteogenic material is a material other than bone.

29. The implant of claim 27, wherein said material is genetic material coding for the production of bone.

30. The implant of claim 27, wherein said material is bone morphogenetic protein.

31. The implant of claim 1, further in combination with genetic material coding for production of bone.

32. The implant of claim 1, further comprising a plurality of openings and passages for retaining fusion promoting substance.

33. The implant of claim 1, wherein said implant has a maximum length less than and approximating the posterior to anterior depth of the vertebral body.

34. The implant of claim 1, wherein said trailing end is adapted to conform from side to side to at least a portion of the peripheral contour of at least one of the anterior and posterior aspects of the vertebral bodies adjacent a disc space into which said implant is inserted.

35. The implant of claim 1, wherein at least a portion of said opposed portions are in a diverging relationship to each other from trailing end to leading end for allowing angulation of the adjacent vertebral bodies relative to each other.

36. The implant of claim 1, wherein at least a portion of said opposed portions are generally in a converging relationship to each other from trailing end to leading end for allowing angulation of the adjacent vertebral bodies relative to each other.

37. The implant of claim 1, in combination with a driver instrument for installing said implant into the spine.