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Combination dosage form containing individual dosage units of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin

  • US 6,669,955 B2
  • Filed: 08/28/2001
  • Issued: 12/30/2003
  • Est. Priority Date: 08/28/2001
  • Status: Expired due to Term
First Claim
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1. An orally administrable pharmaceutical dosage form for treating a patient at an elevated cardiovascular risk, comprising a combination of:

  • (a) a therapeutically effective daily dosage of a cholesterol-lowering agent, as a first active agent;

    (b) a therapeutically effective daily dosage of an inhibitor of the renin-angiotensin system, as a second active agent; and

    (c) a therapeutically effective daily dosage of aspirin, as a third active agent;

    wherein at least one of the active agents is present in a dosage unit that physically separates the at least one active agent from the other active agents, and wherein the effective daily dosage units of each of the active agents of the combination have different release profiles.

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